OXER1 - oxoeicosanoid receptor 1 Gene

Also Known as GPCR; GPR170; TG1019

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 165140

About OXER1

Cytogenetic location: 2p21 Genomic coordinates (GRCh38): 2:42,762,499-42,764,135 (from NCBI)

This gene has 1 transcript (splice variant), 189 orthologues and 15 paralogues.

Summary

Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

OXER1 Products (1)

mRNA Protein Name
NM_148962.5 NP_683765.2 oxoeicosanoid receptor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding IDA
IDA: Inferred from direct assay
12065583 GOA
enables 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding IDA
IDA: Inferred from direct assay
12065583 GOA
enables 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding IDA
IDA: Inferred from direct assay
12065583 GOA
enables G protein-coupled receptor activity IMP
IMP: Inferred from mutant phenotype
12065583 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12065583 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OXER1 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (109 - 355)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 423 a.a.
Protein Preferred Names Protein Names

oxoeicosanoid receptor 1

  • 5-oxo-ETE G-protein coupled receptor

OXER1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
OXER1 Q8TDS5 KRTAP4-2 Homo sapiens Q9BYR5
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 ASB13 Homo sapiens Q8WXK3-2
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 ANAPC11 Homo sapiens Q9NYG5-2
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 RNF38 Homo sapiens Q9H0F5
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 TFG Homo sapiens Q92734
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 NOC4L Homo sapiens Q9BVI4
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 ZC3H10 Homo sapiens Q96K80
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 RAMAC Homo sapiens Q9BTL3
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 RNF208 Homo sapiens Q9H0X6
Validated Y2H
32296183
Intra
OXER1 Q8TDS5 PLSCR4 Homo sapiens Q9NRQ2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Nephrogenic Diabetes Insipidus

  • Vasopressin-Resistant Diabetes Insipidus

  • Diabetes Insipidus, Nephrogenic

  • Diabetes Insipidus Nephrogenic

  • Congenital Nephrogenic Diabetes Insipidus

  • Adh Resistant Diabetes Insipidus

  • Diabetes Insipidus Nephrogenic X-Linked

  • Diabetes Insipidus Nephrogenic Type 1

  • Adh-Resistant Diabetes Insipidus

  • Diabetes Insipidus Renalis

  • Ndi

  • Renal Diabetes Insipidus

  • Familial Nephrogenic Diabetes

  • Antidiuretic-Hormone-Resistant Diabetes Insipidus

  • Adiuretin-Resistant Diabetes Insipidus

  • Ndi - [Nephrogenic Diabetes Insipidus]

  • Diabetes Tenuifluus

  • Adh - [Antidiuretic-Hormone] Resistant Diabetes Insipidus

  • Hereditary Nephrogenic Diabetes Insipidus

  • Familial Nephrogenic Diabetes Insipidus

  • Primary Nephrogenic Diabetes Insipidus
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09887 OXER1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-141434 5-OxoETE methyl ester Agonist / Unkown