RAMAC - RNA guanine-7 methyltransferase activating subunit Gene

Homo sapiens

Also known as RAM; RAMMET; C15orf18; FAM103A1; HsT19360

Gene ID: 83640 | Gene type: protein coding

About RAMAC

Cytogenetic location: 15q25.2 Genomic coordinates (GRCh38): 15:82,986,210-82,991,057 (from NCBI)

This gene has 1 transcript (splice variant), 187 orthologues and 1 paralogue. Ubiquitous expression in placenta (RPKM 19.2), colon (RPKM 16.4) and 25 other tissues.

Summary

Enables RNA binding activity and Enzyme activator activity. Involved in methylation and recruitment of mRNA capping Enzyme to RNA polymerase II holoenzyme complex. Located in nucleoplasm. Part of mRNA cap binding activity complex and mRNA cap methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

RAMAC Products(1)

mRNA	Protein	Name
NM_031452.4	NP_113640.1	RNA guanine-N7 methyltransferase activating subunit

RAMAC Protein Structure

RAM

0
100
118 a.a.

Protein Preferred Names

Protein Names

RNA guanine-N7 methyltransferase activating subunit

RNMT activating mRNA cap methyltransferase subunit

Related Diseases

Diseases

Alias

Murray Valley Encephalitis

Australian Encephalitis	Australian X Disease
Encephalitis Australia	Murray River Encephalitis
Australian Arboencephalitis	Australian X Disorder
Mve - [Murray Valley Encephalitis]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11637	RAMAC Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RAMAC	MGD	MGI:1914398
Rattus norvegicus	RAMAC	RGD	RGD:1310022
Bos taurus	RAMAC	VGNC	VGNC:55894
Canis familiaris	RAMAC	VGNC	VGNC:53171

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