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PRR3 - proline rich 3 Gene

Also Known as CAT56

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 80742

About PRR3

This gene has 6 transcripts (splice variants), 1 gene allele, 100 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 9.9), brain (RPKM 7.4) and 25 other tissues.

Summary

Enables RNA binding activity. [provided by Alliance of Genome Resources, Apr 2022]

PRR3 Products (2)

mRNA	Protein	Name
NM_001077497.3	NP_001070965.1	proline-rich protein 3 isoform b
NM_025263.4	NP_079539.2	proline-rich protein 3 isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRR3 Protein Structure

zf-CCCH

0
100
188 a.a.

Protein Preferred Names	Protein Names
proline-rich protein 3	MHC class I region proline-rich protein CAT56

PRR3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	PRR3	P79522	FKBP1A	Homo sapiens	Q0VDC6	Y2H Array	32814053
Intra	PRR3	P79522	FKBP1A	Homo sapiens	Q0VDC6	Validated Y2H	32814053
Intra	PRR3	P79522	FKBP1A	Homo sapiens	Q0VDC6	Y2H Pooling	32814053
Intra	PRR3	P79522	APOBEC3C	Homo sapiens	Q9NRW3	Validated Y2H	32296183
Intra	PRR3	P79522	SARS1	Homo sapiens	P49591	Validated Y2H	32814053
Intra	PRR3	P79522	SARS1	Homo sapiens	P49591	Y2H Array	32814053
Intra	PRR3	P79522	SARS1	Homo sapiens	P49591	Y2H Pooling	32814053
Intra	PRR3	P79522	TLE5	Homo sapiens	Q08117-2	Y2H Array	32296183
Intra	PRR3	P79522	TLE5	Homo sapiens	Q08117-2	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	TLE5	Homo sapiens	Q08117-2	Validated Y2H	32296183
Intra	PRR3	P79522	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	KRTAP6-2	Homo sapiens	Q3LI66	Validated Y2H	32296183
Intra	PRR3	P79522	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Array	32296183
Intra	PRR3	P79522	RBMY1A1	Homo sapiens	P0DJD3-2	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	RBMY1A1	Homo sapiens	P0DJD3-2	Y2H Array	32296183
Intra	PRR3	P79522	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	KRTAP6-3	Homo sapiens	Q3LI67	Y2H Array	32296183
Intra	PRR3	P79522	CLP1	Homo sapiens	Q92989	Validated Y2H	32296183
Intra	PRR3	P79522	CCDC57	Homo sapiens	Q2TAC2	Y2H Prey Pooling	25416956
Intra	PRR3	P79522	MYPOP	Homo sapiens	Q86VE0	Validated Y2H	32296183
Intra	PRR3	P79522	RBM3	Homo sapiens	P98179	Validated Y2H	32296183
Intra	PRR3	P79522	HNRNPK	Homo sapiens	P61978	Y2H Prey Pooling	25416956
Intra	PRR3	P79522	HNRNPK	Homo sapiens	P61978	Validated Y2H	25416956
Intra	PRR3	P79522	HNRNPK	Homo sapiens	P61978	Y2H Array	25416956
Intra	PRR3	P79522	HNRNPK	Homo sapiens	P61978	Y2H Array	29892012
Intra	PRR3	P79522	HNRNPK	Homo sapiens	P61978	Anti Tag CoIP	33961781
Intra	PRR3	P79522	PSMA3	Homo sapiens	P25788	Y2H Array	25416956
Intra	PRR3	P79522	NXF1	Homo sapiens	Q9UBU9	Validated Y2H	32296183
Intra	PRR3	P79522	HNRNPK	Homo sapiens	P61978-2	Y2H Array	32296183
Intra	PRR3	P79522	HNRNPK	Homo sapiens	P61978-2	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	TLE5	Homo sapiens	Q08117	Validated Y2H	25416956
Intra	PRR3	P79522	KHDRBS3	Homo sapiens	O75525	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	KHDRBS3	Homo sapiens	O75525	Y2H Array	32296183
Intra	PRR3	P79522	KHDRBS2	Homo sapiens	Q5VWX1	Validated Y2H	25416956
Intra	PRR3	P79522	KHDRBS2	Homo sapiens	Q5VWX1	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	KHDRBS2	Homo sapiens	Q5VWX1	Validated Y2H	32296183
Intra	PRR3	P79522	KHDRBS2	Homo sapiens	Q5VWX1	Y2H Array	32296183
Intra	PRR3	P79522	RBMX	Homo sapiens	P38159	Validated Y2H	25416956
Intra	PRR3	P79522	RBMX	Homo sapiens	P38159	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	RBMX	Homo sapiens	P38159	Y2H Array	32296183
Intra	PRR3	P79522	RBMX	Homo sapiens	P38159	Y2H Prey Pooling	25416956
Intra	PRR3	P79522	RAMAC	Homo sapiens	Q9BTL3	Validated Y2H	32296183
Intra	PRR3	P79522	ASF1A	Homo sapiens	Q9Y294	Y2H Array	32296183
Intra	PRR3	P79522	ASF1A	Homo sapiens	Q9Y294	Validated Y2H	32296183
Intra	PRR3	P79522	ASF1A	Homo sapiens	Q9Y294	Y2H Prey Pooling	25416956
Intra	PRR3	P79522	ASF1A	Homo sapiens	Q9Y294	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	ASF1A	Homo sapiens	Q9Y294	Y2H Array	25416956
Intra	PRR3	P79522	KLF1	Homo sapiens	Q13351	Y2H Array	32296183
Intra	PRR3	P79522	KLF1	Homo sapiens	Q13351	Y2H Prey Pooling	32296183
Intra	PRR3	P79522	KLF1	Homo sapiens	Q13351	Validated Y2H	32296183
Intra	PRR3	P79522	RBMY1A1	Homo sapiens	P0DJD3	Validated Y2H	25416956
Intra	PRR3	P79522	RBMY1A1	Homo sapiens	P0DJD3	Y2H Array	25416956
Intra	PRR3	P79522	RBMY1A1	Homo sapiens	P0DJD3	Y2H Prey Pooling	25416956
Intra	PRR3	P79522	RBMY1F	Homo sapiens	Q15415	Validated Y2H	32296183
Intra	PRR3	P79522	RBMY1F	Homo sapiens	Q15415	Validated Y2H	25416956
Intra	PRR3	P79522	RBMY1F	Homo sapiens	Q15415	Y2H Array	32296183
Intra	PRR3	P79522	RBMY1F	Homo sapiens	Q15415	Y2H Array	25416956
Intra	PRR3	P79522	RBMY1F	Homo sapiens	Q15415	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Hyperoxaluria, Primary, Type Ii	Primary Hyperoxaluria Type 2 D-Glycerate Dehydrogenase Deficiency Glyoxylate Reductase/Hydroxypyruvate Reductase Deficiency HP2 Oxalosis Ii Glyceric Aciduria L-Glyceric Aciduria Primary Hyperoxaluria, Type Ii Oxalosis 2 Hyperoxaluria Primary 2 Hyperoxaluria Primary Type Ii Ph2 Primary Hyperoxaluria Type Ii

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09176	NECTIN3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS11229	PRR3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20330	Prr3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26838	Prr3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRR3	RGD	RGD:1303270
Mus musculus	PRR3	MGD	MGI:1922460
Bos taurus	PRR3	VGNC	VGNC:33396
Felis catus	PRR3	VGNC	VGNC:102496
Macaca mulatta	PRR3	VGNC	VGNC:76297
Others	PRR3	NCBI