NAF1 - nuclear assembly factor 1 ribonucleoprotein Gene

Homo sapiens

Gene ID: 92345 | Gene type: protein coding

About NAF1

Cytogenetic location: 4q32.2 Genomic coordinates (GRCh38): 4:163,103,929-163,166,890 (from NCBI)

This gene has 6 transcripts (splice variants) and 188 orthologues. Ubiquitous expression in testis (RPKM 1.9), endometrium (RPKM 1.8) and 25 other tissues.

Summary

Enables identical protein binding activity and Telomerase RNA binding activity. Involved in regulation of nucleobase-containing compound metabolic process; ribosome biogenesis; and Telomerase holoenzyme complex assembly. Located in nucleoplasm. Part of sno(s)RNA-containing ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]

NAF1 Products(2)

mRNA	Protein	Name
NM_001128931.2	NP_001122403.1	H/ACA ribonucleoprotein complex non-core subunit NAF1 isoform b
NM_138386.3	NP_612395.2	H/ACA ribonucleoprotein complex non-core subunit NAF1 isoform a

NAF1 Protein Structure

Gar1

0
100
200
300
400
494 a.a.

Protein Preferred Names

Protein Names

H/ACA ribonucleoprotein complex non-core subunit NAF1

nuclear assembly factor 1 homolog

Related Diseases

Diseases

Alias

Dyskeratosis Congenita

Dyskeratosis Congenita Autosomal Dominant	Dc
Dkc	Zinsser-Engman-Cole Syndrome
Dyskeratosis Congenita, Autosomal Dominant	Autosomal Dominant Dyskeratosis Congenita
Dkca	Dyskeratosis Congenita Scoggins Type
Zinsser-Cole-Engman Syndrome	X-Linked Dyskeratosis Congenita
Hoyeraal-Hreidarsson Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09008	NAF1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NAF1	MGD	MGI:2682306
Macaca mulatta	NAF1	VGNC	VGNC:75020
Rattus norvegicus	NAF1	RGD	RGD:1306802
Bos taurus	NAF1	VGNC	VGNC:54460
Felis catus	NAF1	VGNC	VGNC:63712