MIEN1 - migration and invasion enhancer 1 Gene

Homo sapiens

Also known as C35; ORB3; XTP4; RDX12; C17orf37

Gene ID: 84299 | Gene type: protein coding

About MIEN1

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:39,728,510-39,730,532 (from NCBI)

This gene has 6 transcripts (splice variants), 196 orthologues and 2 paralogues. Ubiquitous expression in colon (RPKM 15.4), esophagus (RPKM 14.3) and 25 other tissues.

Summary

Involved in negative regulation of apoptotic process; positive regulation of cell migration; and positive regulation of filopodium assembly. Located in several cellular components, including centriolar satellite; cytosol; and nucleoplasm. Is intrinsic component of the cytoplasmic side of the plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MIEN1 Products(2)

mRNA	Protein	Name
NM_001330206.2	NP_001317135.1	migration and invasion enhancer 1 isoform 2
NM_032339.5	NP_115715.3	migration and invasion enhancer 1 isoform 1

MIEN1 Protein Structure

Rdx

0
100
115 a.a.

Protein Preferred Names

Protein Names

migration and invasion enhancer 1

HBV X-transactivated gene 4 protein

Related Diseases

Diseases

Alias

Breast Large Cell Neuroendocrine Carcinoma

Prostate Cancer

Prostate Carcinoma	Prostate Cancer, Familial
Prostate Neoplasm	Prostate Cancer, Somatic
Prostate Cancer, Susceptibility To	Prostatic Cancer
Prostatic Neoplasms	Hereditary Prostate Cancer
Prostatic Neoplasm	Cancer Of Prostate
Carcinoma Of Prostate	Familial Prostate Cancer
Familial Prostate Carcinoma	Malignant Tumor Of Prostate
Malignant Neoplasm Of Prostate	Prostate Cancer, Familial, Susceptibility To
Malignant Tumor Of The Prostate	Ngp - New Growth Of Prostate
Tumor Of The Prostate	Prostate Cancer, Hereditary
Cancer Of The Prostate	Malignant Neoplasm Of The Prostate
Prostatic Carcinoma	PC
Prca	Cancer, Prostate
Malignant Prostatic Tumour	Malignant Tumour Of Prostate
Primary Prostate Cancer	Primary Malignant Neoplasm Of Prostate
Prostate Gland Cancer

Brain Cancer

Adult Brain Tumor	Malignant Neoplasm Of Brain
Brain Neoplasms	Brain Neoplasm
Neoplasm Of Brain	Primary Malignant Neoplasm Of Brain
Brain Tumors	Adult Malignant Brain Neoplasm
Brain Neoplasm, Adult	Bt - Brain Tumour
Malignant Brain Tumour	Malignant Primary Brain Neoplasm
Malignant Primary Brain Tumor	Malignant Tumor Of Adult Brain
Malignant Tumor Of Brain	Primary Brain Neoplasm
Primary Brain Tumor	Tumor Of The Brain
Brain Tumor, Adult	Brain Tumor Primary
Malignant Primary Brain Tumors	Primary Brain Tumors
Cancer, Brain	Brain Tumor, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08441	MIEN1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MIEN1	VGNC	VGNC:63499
Mus musculus	MIEN1	MGD	MGI:1913678
Bos taurus	MIEN1	VGNC	VGNC:31468
Rattus norvegicus	MIEN1	RGD	RGD:1306682
Canis familiaris	MIEN1	VGNC	VGNC:43228

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