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92181

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16

Inhibitors & Agonists

8

Antibodies

9

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134829
    BMS-986176

    LX-9211; AAK1-IN-1

    		 AAK1 Neurological Disease
    BMS-986176 (LX-9211) is a highly selective, brain-penetrant, potent AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2 nM. BMS-986176 can be used for neurodegenerative diseases research .
    BMS-986176
  • HY-111151
    AR-9281

    APAU

    		 Epoxide Hydrolase Infection Cardiovascular Disease Metabolic Disease
    AR9281 (APAU) is a potent, selective and orally active soluble epoxide hydrolase (s-EH) inhibitor. AR-9281 can inhibits human sEH (HsEH) and murine sEH (MsEH) with IC50 values of 13.8 nM and 1.7 nM, respectively. AR9281 can be used for the research of inflammation, hypertension and type 2 diabetes .
    AR-9281
  • HY-177437A
    (+)-PM 92131

    		HIV Infection
    (+)-PM 92131 is the active enantiomer of (±)-PM 92131 (HY-177437). (+)-PM 92131 is a non-nucleoside HIV-1 inhibitor. (+)-PM 92131 has an anti-HIV-1 activity with EC50s of 0.8 and 0.6 μM for HIV-1 RF strain in XTT cytoprotection and syncytium-forming assay, respectively. (+)-PM 92131 can be used for HIV infections research .
    (+)-PM 92131
  • HY-177437
    (±)-PM 92131

    		HIV Infection
    (±)-PM 92131 is a non-nucleoside HIV-1 inhibitor. (±)-PM 92131 has an anti-HIV-1 activity with IC50s of 45.7 and 53.8 μM for HIV-1 RF strain in XTT cytoprotection and syncytium-forming assay, respectively. (±)-PM 92131 can be used for HIV infections research .
    (±)-PM 92131
  • HY-176039
    TUG-2181

    		GPR84 Reactive Oxygen Species (ROS) Inflammation/Immunology
    TUG-2181 is an antagonist of GPR84 with an IC50 value of 34 nM. TUG-2181 inhibits GPR84 agonists-induced reactive species oxygen (ROS) production and IL-8 release in human neutrophils. TUG-2181 can be used for inflammation and fibrosis study .
    TUG-2181
  • HY-157997
    MHC02181

    		Phosphodiesterase (PDE) Cancer
    MHC02181 is a potent inhibitor of Autotaxin (ATX), with IC50 of 9.41 μM .
    MHC02181
  • HY-RI02594A
    mmu-miR-12181-5p antagomir

    		MicroRNA Cancer
    mmu-miR-12181-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-12181-5p antagomir
    mmu-miR-12181-5p antagomir
  • HY-R02594
    mmu-miR-12181-5p mimic

    		MicroRNA Cancer
    mmu-miR-12181-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-12181-5p mimic
    mmu-miR-12181-5p mimic
  • HY-R02594A
    mmu-miR-12181-5p agomir

    		MicroRNA Cancer
    mmu-miR-12181-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-12181-5p agomir
    mmu-miR-12181-5p agomir
  • HY-RI02593A
    mmu-miR-12181-3p antagomir

    		MicroRNA Cancer
    mmu-miR-12181-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-12181-3p antagomir
    mmu-miR-12181-3p antagomir
  • HY-111151R
    AR-9281 (Standard)

    APAU (Standard)

    		 Epoxide Hydrolase Reference Standards Infection Cardiovascular Disease Metabolic Disease
    AR-9281 (Standard) is the analytical standard of AR-9281. This product is intended for research and analytical applications. AR9281 (APAU) is a potent, selective and orally active soluble epoxide hydrolase (s-EH) inhibitor. AR-9281 can inhibits human sEH (HsEH) and murine sEH (MsEH) with IC50 values of 13.8 nM and 1.7 nM, respectively. AR9281 can be used for the research of inflammation, hypertension and type 2 diabetes .
    AR-9281 (Standard)
  • HY-R02593A
    mmu-miR-12181-3p agomir

    		MicroRNA Cancer
    mmu-miR-12181-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-12181-3p agomir
    mmu-miR-12181-3p agomir
  • HY-RI02593
    mmu-miR-12181-3p inhibitor

    		MicroRNA Cancer
    mmu-miR-12181-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-12181-3p inhibitor
    mmu-miR-12181-3p inhibitor
  • HY-RI02594
    mmu-miR-12181-5p inhibitor

    		MicroRNA Cancer
    mmu-miR-12181-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-12181-5p inhibitor
    mmu-miR-12181-5p inhibitor
  • HY-R02593
    mmu-miR-12181-3p mimic

    		MicroRNA Cancer
    mmu-miR-12181-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-12181-3p mimic
    mmu-miR-12181-3p mimic
  • HY-N16069
    2-18:1 Lyso PE

    		Others Metabolic Disease
    2-18:1 Lyso PEis a lysophosphatidylethanolamine.
    2-18:1 Lyso PE

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