TGM7 - transglutaminase 7 Gene

Homo sapiens

Also known as TGMZ

Gene ID: 116179 | Gene type: protein coding

About TGM7

Cytogenetic location: 15q15.2-q15.3 Genomic coordinates (GRCh38): 15:43,276,271-43,302,255 (from NCBI)

This gene has 2 transcripts (splice variants), 121 orthologues and 8 paralogues. Low expression observed in reference dataset.

Summary

Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).[supplied by OMIM, Jul 2002]

TGM7 Products(1)

mRNA	Protein	Name
NM_052955.3	NP_443187.1	protein-glutamine gamma-glutamyltransferase Z

TGM7 Protein Structure

Transglut_N

Transglut_core

Transglut_C

0
200
400
600
710 a.a.

Protein Preferred Names

Protein Names

protein-glutamine gamma-glutamyltransferase Z

TG(Z)

Related Diseases

Diseases

Alias

Retinal Lattice Degeneration

Palisade Degeneration Of Retina

Lattice Retinal Degeneration

Richter'S Syndrome

Richter Syndrome

Richter Transformation

Gingival Fibromatosis

Hereditary Gingival Fibromatosis	Hereditary Gingival Hyperplasia
Autosomal Dominant Gingival Fibromatosis	Autosomal Dominant Gingival Hyperplasia
Fibromatosis, Gingival, Hereditary	Fibromatosis, Gingival

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14464	TGM7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TGM7	RGD	RGD:7615199
Canis familiaris	TGM7	VGNC	VGNC:47320
Felis catus	TGM7	VGNC	VGNC:66145
Mus musculus	TGM7	MGD	MGI:2151164
Bos taurus	TGM7	VGNC	VGNC:35814
Macaca mulatta	TGM7	VGNC	VGNC:79880