XAGE2 - X antigen family member 2 Gene

Also Known as CT12.2; GAGED3; XAGE-2; XAGE2B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9502

Summary

This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of Tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a Breast Cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) Antigens. [provided by RefSeq, Jul 2008]
Restricted expression toward placenta (RPKM 70.1).

XAGE2 Products (1)

mRNA Protein Name
NM_130777.3 NP_570133.1 X antigen family member 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

XAGE2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
XAGE2 Q96GT9 GMCL1 Homo sapiens Q96IK5
Y2H Prey Pooling
32296183
Intra
XAGE2 Q96GT9 GMCL1 Homo sapiens Q96IK5
Anti Tag CoIP
33961781
Intra
XAGE2 Q96GT9 GMCL1 Homo sapiens Q96IK5
Anti Tag CoIP
28514442
Intra
XAGE2 Q96GT9 GMCL1 Homo sapiens Q96IK5
Validated Y2H
32296183
Intra
XAGE2 Q96GT9 GMCL1 Homo sapiens Q96IK5
Y2H Array
32296183
Intra
XAGE2 Q96GT9 EHMT2 Homo sapiens Q96KQ7
Y2H Pooling
16189514
Intra
XAGE2 Q96GT9 EHMT2 Homo sapiens Q96KQ7
Anti Tag CoIP
33961781
Intra
XAGE2 Q96GT9 GMCL2 Homo sapiens Q8NEA9
Y2H Array
25416956
Intra
XAGE2 Q96GT9 TERF2IP Homo sapiens Q9NYB0
Pull Down
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09973 PAGE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown