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64395

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11

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Recombinant Proteins

2

Isotope-Labeled Compounds

8

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112218
    MIK665
    Maximum Cited Publications
    17 Publications Verification

    S-64315

    		 Bcl-2 Family Cancer
    MIK665 (S-64315), derived from S63845, is a myeloid cell leukemia sequence 1 (MCL1) inhibitor . MIK665 has an IC50 of 1.81 nM for MCL1 .
    MIK665
  • HY-B0674
    Ebastine
    1 Publications Verification

    LAS-W 090; RP64305

    		 Histamine Receptor Inflammation/Immunology Endocrinology
    Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research .
    Ebastine
  • HY-12664
    AF64394
    1 Publications Verification

    		 Orphan GPCR Others
    AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.
    AF64394
  • HY-P99671
    Isecarosmab

    M-6495

    		 ADAMTS Inflammation/Immunology
    Isecarosmab (M-6495) is an anti-ADAMTS monoclonal antibody (mAb) with a KD value of 3.65 pM. Isecarosmab has chondroprotective and anti-inflammatory activities. Isecarosmab can bind albumin to extend plasma half-life .
    Isecarosmab
  • HY-R03402A
    mmu-miR-6395 agomir

    		MicroRNA Cancer
    mmu-miR-6395 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6395 agomir
    mmu-miR-6395 agomir
  • HY-R03402
    mmu-miR-6395 mimic

    		MicroRNA Cancer
    mmu-miR-6395 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6395 mimic
    mmu-miR-6395 mimic
  • HY-B0674R
    Ebastine (Standard)

    LAS-W 090 (Standard); RP64305 (Standard)

    		 Reference Standards Histamine Receptor Inflammation/Immunology Endocrinology
    Ebastine (Standard) is the analytical standard of Ebastine. This product is intended for research and analytical applications. Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research .
    Ebastine (Standard)
  • HY-143955S
    Ebastine-d5 fumarate

    LAS-W 090-d5 fumarate; RP64305-d5 fumarate

    		 Isotope-Labeled Compounds Others
    Ebastine-d5 (fumarate) is the deuterium labeled Ebastine fumarate .
    Ebastine-d5 fumarate
  • HY-B0674S1
    Ebastine-d6

    LAS-W 090-d6; RP64305-d6

    		 Histamine Receptor Isotope-Labeled Compounds Inflammation/Immunology Endocrinology
    Ebastine-d6 is deuterated labeled Ebastine (HY-B0674). Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research .
    Ebastine-d6
  • HY-RI03402A
    mmu-miR-6395 antagomir

    		MicroRNA Cancer
    mmu-miR-6395 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6395 antagomir
    mmu-miR-6395 antagomir
  • HY-RI03402
    mmu-miR-6395 inhibitor

    		MicroRNA Cancer
    mmu-miR-6395 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6395 inhibitor
    mmu-miR-6395 inhibitor

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