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Cat. No.: HY-130261

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Mcl-1 antagonist 1

Mcl-1 antagonist 1 is a Mcl-1 protein antagonist extracted from patent WO2019173181, compound 200.

For research use only. We do not sell to patients.

CAS No.: 2376775-05-0
Formula: C₄₁H₅₄ClF₂N₅O₈S
Molecular Weight:850.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Mcl-1 antagonist 1 Chemical Structure

CAS No.: 2376775-05-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Mcl-1 antagonist 1 is a Mcl-1 protein antagonist extracted from patent WO2019173181, compound 200^[1].

All Bcl-2 Family Isoforms :

Chemical Information

CAS No. 2376775-05-0
Molecular Weight 850.41
Formula C₄₁H₅₄ClF₂N₅O₈S
SMILES

ClC1=CC=C2C(CCC[C@]23COC4=C(N(C3)C[C@@H]5CC[C@H]5[C@H](/C=C/CCN(C)C(C[C@]6(O)C(NS(=O)(N(CCO)C)=O)=O)=O)OCCN7CC(F)(C7)F)C=C6C=C4)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gwenaella Rescourio, et al. Alpha-hydroxy phenylacetic acid pharmacophore or bioisostere mcl-1 protein antagonists. WO2019173181.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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