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Cat. No.: HY-154962

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Mcl-1 inhibitor 15

Mcl-1 inhibitor 15 (Compound (Ra)-15) is a Mcl-1 inhibitor (K_i: 0.02 nM). Mcl-1 inhibitor 15 can be used for research of cancer.

For research use only. We do not sell to patients.

CAS No.: 2750555-36-1
Formula: C₄₀H₄₂ClFN₆O₄S
Molecular Weight:757.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Mcl-1 inhibitor 15 Chemical Structure

CAS No.: 2750555-36-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Mcl-1 inhibitor 15 (Compound (Ra)-15) is a Mcl-1 inhibitor (K_i: 0.02 nM). Mcl-1 inhibitor 15 can be used for research of cancer^[1].

All Bcl-2 Family Isoforms :

Chemical Information

CAS No. 2750555-36-1
Molecular Weight 757.32
Formula C₄₀H₄₂ClFN₆O₄S
SMILES

CN1N=CC(CSCC2=NN(C)C(CCC3=CC(C=C(C=C4)F)=C4C(OCCCC5=C6C(O)=O)=C3)=C2)=C1C(C(Cl)=CC=C57)=C7N6CCN8CCOCC8
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Demin S, et al. Macrocyclic Carbon-Linked Pyrazoles As Novel Inhibitors of MCL-1. ACS Med Chem Lett. 2023 Jul 3;14(7):955-961. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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Mcl-1 inhibitor 15

All Bcl-2 Family Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Mcl-1 inhibitor 15 Related Classifications

HY-154962 Related Classifications