FAM50B - family with sequence similarity 50 member B Gene

Also Known as X5L; D6S2654E

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26240

Summary

This gene contains an intronless ORF that arose from ancestral retroposition. The encoded protein is related to a plant protein that plays a role in the circadian clock. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and paternally expressed in many tissues. [provided by RefSeq, Nov 2015]
Ubiquitous expression in kidney (RPKM 6.3), testis (RPKM 5.1) and 25 other tissues.

FAM50B Products (1)

mRNA Protein Name
NG_045226.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19060904 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM50B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FAM50B Q9Y247 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
FAM50B Q9Y247 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
FAM50B Q9Y247 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra
FAM50B Q9Y247 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra
FAM50B Q9Y247 TFIP11 Homo sapiens Q9UBB9
Y2H Array
25416956
Intra
FAM50B Q9Y247 CDR2 Homo sapiens Q01850
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 CDR2 Homo sapiens Q01850
Y2H Array
32296183
Intra
FAM50B Q9Y247 TCF12 Homo sapiens Q99081-3
Y2H Array
32296183
Intra
FAM50B Q9Y247 TCF12 Homo sapiens Q99081-3
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 BICD2 Homo sapiens Q8TD16-2
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 BICD2 Homo sapiens Q8TD16-2
Y2H Array
32296183
Intra
FAM50B Q9Y247 TACC1 Homo sapiens O75410-7
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 TACC1 Homo sapiens O75410-7
Y2H Array
32296183
Intra
FAM50B Q9Y247 ZMYND12 Homo sapiens Q9H0C1
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 ZMYND12 Homo sapiens Q9H0C1
Y2H Array
32296183
Intra
FAM50B Q9Y247 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra
FAM50B Q9Y247 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra
FAM50B Q9Y247 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 CCDC89 Homo sapiens Q8N998
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 CCDC89 Homo sapiens Q8N998
Y2H Array
32296183
Intra
FAM50B Q9Y247 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
FAM50B Q9Y247 TBC1D1 Homo sapiens Q86TI0
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 TBC1D1 Homo sapiens Q86TI0
Y2H Array
32296183
Intra
FAM50B Q9Y247 VAC14 Homo sapiens Q08AM6
Y2H Array
32296183
Intra
FAM50B Q9Y247 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
FAM50B Q9Y247 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 MID1 Homo sapiens O15344
Y2H Array
32296183
Intra
FAM50B Q9Y247 MID1 Homo sapiens O15344
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 GMCL1 Homo sapiens Q96IK5
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 GMCL1 Homo sapiens Q96IK5
Y2H Array
32296183
Intra
FAM50B Q9Y247 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra
FAM50B Q9Y247 CCDC57 Homo sapiens Q2TAC2
Validated Y2H
25416956
Intra
FAM50B Q9Y247 TRIM14 Homo sapiens Q14142
Y2H Array
32296183
Intra
FAM50B Q9Y247 TRIM14 Homo sapiens Q14142
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
FAM50B Q9Y247 CCNC Homo sapiens P24863
Y2H Array
32296183
Intra
FAM50B Q9Y247 CCNC Homo sapiens P24863
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 KPNA4 Homo sapiens O00629
Y2H Array
32296183
Intra
FAM50B Q9Y247 KPNA4 Homo sapiens O00629
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 RABEP1 Homo sapiens Q15276
Y2H Array
32296183
Intra
FAM50B Q9Y247 RABEP1 Homo sapiens Q15276
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
FAM50B Q9Y247 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 FSD2 Homo sapiens A1L4K1
Y2H Array
32296183
Intra
FAM50B Q9Y247 FSD2 Homo sapiens A1L4K1
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 GOLGA2 Homo sapiens Q08379
Validated Y2H
25416956
Intra
FAM50B Q9Y247 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
Intra
FAM50B Q9Y247 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
FAM50B Q9Y247 HAP1 Homo sapiens P54257
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 HAP1 Homo sapiens P54257
Y2H Array
32296183
Intra
FAM50B Q9Y247 GRIPAP1 Homo sapiens Q4V328
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 GRIPAP1 Homo sapiens Q4V328
Y2H Array
32296183
Intra
FAM50B Q9Y247 LDOC1 Homo sapiens O95751
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 LDOC1 Homo sapiens O95751
Y2H Array
31515488
Intra
FAM50B Q9Y247 LDOC1 Homo sapiens O95751
Y2H Array
32296183
Intra
FAM50B Q9Y247 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 LZTS2 Homo sapiens Q9BRK4
Y2H Array
32296183
Intra
FAM50B Q9Y247 TRIM37 Homo sapiens O94972
Validated Y2H
25416956
Intra
FAM50B Q9Y247 TRIM37 Homo sapiens O94972
Y2H Array
25416956
Intra
FAM50B Q9Y247 GFAP Homo sapiens P14136
Validated Y2H
25416956
Intra
FAM50B Q9Y247 IKZF1 Homo sapiens Q13422
Validated Y2H
25416956
Intra
FAM50B Q9Y247 IKZF1 Homo sapiens Q13422
Y2H Prey Pooling
25416956
Intra
FAM50B Q9Y247 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra
FAM50B Q9Y247 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 PAX6 Homo sapiens P26367
Y2H Array
32296183
Intra
FAM50B Q9Y247 DEUP1 Homo sapiens Q05D60
Y2H Array
32296183
Intra
FAM50B Q9Y247 DEUP1 Homo sapiens Q05D60
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra
FAM50B Q9Y247 CARD9 Homo sapiens Q9H257
Validated Y2H
25416956
Intra
FAM50B Q9Y247 CARD9 Homo sapiens Q9H257
Y2H Array
25416956
Intra
FAM50B Q9Y247 CARD9 Homo sapiens Q9H257
Y2H Prey Pooling
25416956
Intra
FAM50B Q9Y247 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
FAM50B Q9Y247 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
FAM50B Q9Y247 PDE4DIP Homo sapiens Q5VU43-2
Y2H Array
32296183
Intra
FAM50B Q9Y247 PDE4DIP Homo sapiens Q5VU43-2
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04705 FAM20B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04716 FAM50A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04717 FAM53B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21854 Fam20b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28371 Fam20b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown