KASH5 - KASH domain containing 5 Gene

Homo sapiens

Also known as CCDC155

Gene ID: 147872 | Gene type: protein coding

About KASH5

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,388,249-49,417,990 (from NCBI)

This gene has 15 transcripts (splice variants), 91 orthologues and 30 paralogues. Restricted expression toward testis (RPKM 13.2).

Summary

Predicted to enable dynein complex binding activity. Predicted to be involved in several processes, including Cytoskeleton organization; homologous chromosome segregation; and spindle localization. Predicted to act upstream of or within double-strand break repair via homologous recombination; oogenesis; and spermatogenesis. Predicted to be integral component of membrane. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in chromosome; meiotic spindle pole; and nuclear outer membrane. [provided by Alliance of Genome Resources, Apr 2022]

KASH5 Products(1)

mRNA	Protein	Name
NM_144688.5	NP_653289.3	protein KASH5

KASH5 Protein Structure

EF-hand_9

KASH_CCD

0
100
200
300
400
500
562 a.a.

Protein Preferred Names

Protein Names

protein KASH5

KASH domain-containing protein 5

Related Diseases

Diseases

Alias

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Genetic Non-Acquired Premature Ovarian Failure

Muscular Dystrophy, Congenital, Lmna-Related

Congenital Muscular Dystrophy	Congenital Muscular Dystrophy Due To Lmna Mutation
MDCL	L-Cmd
Lmna-Related Congenital Muscular Dystrophy	Muscular Dystrophy, Congenital
Congenital Muscular Dystrophy Lmna-Related	Lmna-Related Cmd
Cmd	Mdc
Muscular Dystrophy Congenital Lmna-Related	Dystrophy, Muscular, Congenital, Lmna-Related
Dystrophy, Muscular, Congenital	Hereditary Muscular Dystrophy
Congenital Hereditary Muscular Dystrophy	Congenital Progressive Muscular Dystrophy
Hereditary Progressive Muscular Dystrophy

Emery-Dreifuss Muscular Dystrophy

Edmd	Emery-Dreifuss Syndrome
Muscular Dystrophy, Emery-Dreifuss	Humeroperoneal Neuromuscular Disease
Muscular Dystrophy, Tardive, Dreifuss-Emery Type, With Contractures	Scapuloperoneal Syndrome, X-Linked
Benign Scapuloperoneal Muscular Dystrophy With Early Contractures	Muscular Dystrophy, Emery-Dreifuss Type
Muscular Dystrophy Emery-Dreifuss	Dystrophy, Muscular, Emery-Dreifuss
Emd - [Emery-Dreifuss Muscular Dystrophy]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07072	KASH5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	KASH5	VGNC	VGNC:38805
Mus musculus	KASH5	MGD	MGI:2687329
Bos taurus	KASH5	VGNC	VGNC:26860
Rattus norvegicus	KASH5	RGD	RGD:1561972
Macaca mulatta	KASH5	VGNC	VGNC:70871
Felis catus	KASH5	VGNC	VGNC:60471

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