2. Gene
  3. VTI1B - vesicle transport through interaction with t-SNAREs 1B Gene

VTI1B - vesicle transport through interaction with t-SNAREs 1B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as VTI1; VTI2; VTI1L; v-SNARE; vti1-rp1; VTI1-LIKE

Gene ID: 10490 | Gene type: protein coding

About VTI1B

Cytogenetic location: 14q24.1 Genomic coordinates (GRCh38): 14:67,647,085-67,674,632 (from NCBI)

This gene has 6 transcripts (splice variants), 201 orthologues and 2 paralogues. Ubiquitous expression in fat (RPKM 68.1), kidney (RPKM 45.6) and 25 other tissues.

Summary

Enables SNARE binding activity and Chloride Channel Inhibitor activity. Involved in regulation of protein localization to plasma membrane. Located in several cellular components, including endosome membrane; lysosomal membrane; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

VTI1B Products(1)

mRNA Protein Name
NM_006370.3 NP_006361.1 vesicle transport through interaction with t-SNAREs homolog 1B

VTI1B Protein Structure

V-SNARE

V-SNARE: Vesicle transport v-SNARE protein N-terminus (18 - 96)

V-SNARE_C

V-SNARE_C: Snare region anchored in the vesicle membrane C-terminus (137 - 202)

  • 0
  • 100
  • 200
  • 232 a.a.
Protein Preferred Names Protein Names

vesicle transport through interaction with t-SNAREs homolog 1B

vesicle transport v-SNARE protein Vti1-like 1

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FHL4

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Hlh4

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Tetanus

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Infection Due To Clostridium Tetani

Lock-Jaw
Hermansky-Pudlak Syndrome

Hps

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Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

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Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15723 VTI1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus VTI1B MGD MGI:1855688
Macaca mulatta VTI1B VGNC VGNC:99341
Rattus norvegicus VTI1B RGD RGD:2323682
Felis catus VTI1B VGNC VGNC:80781
Bos taurus VTI1B VGNC VGNC:36849
Canis familiaris VTI1B VGNC VGNC:48317