2. Gene
  3. TRIM59 - tripartite motif containing 59 Gene

TRIM59 - tripartite motif containing 59 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MRF1; TSBF1; IFT80L; RNF104; TRIM57

Gene ID: 286827 | Gene type: protein coding

About TRIM59

Cytogenetic location: 3q25.33 Genomic coordinates (GRCh38): 3:160,435,503-160,449,786 (from NCBI)

This gene has 8 transcripts (splice variants), 130 orthologues and 1 paralogue. Broad expression in testis (RPKM 4.6), lymph node (RPKM 4.6) and 21 other tissues.

Summary

Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

TRIM59 Products(1)

mRNA Protein Name
NM_173084.3 NP_775107.1 tripartite motif-containing protein 59

TRIM59 Protein Structure

zf-RING_2

zf-RING_2: Ring finger domain (9 - 60)

zf-B_box

zf-B_box: B-box zinc finger (95 - 133)

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  • 403 a.a.
Protein Preferred Names Protein Names

tripartite motif-containing protein 59

RING finger protein 104

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15059 TRIM59 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TRIM59 VGNC VGNC:47829
Felis catus TRIM59 VGNC VGNC:101467
Macaca mulatta TRIM59 VGNC VGNC:79887
Bos taurus TRIM59 VGNC VGNC:36344
Rattus norvegicus TRIM59 RGD RGD:1311956
Mus musculus TRIM59 MGD MGI:1914199