PLLP - plasmolipin Gene
Also Known as PMLP; TM4SF11
生物種: Homo sapiens
About PLLP
This gene has 5 transcripts (splice variants), 201 orthologues and 14 paralogues. Broad expression in brain (RPKM 41.3), stomach (RPKM 28.7) and 17 other tissues.
Summary
Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be located in compact myelin and membrane raft. Predicted to be integral component of membrane. Biomarker of Schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]
PLLP Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_015993.3 | NP_057077.1 | plasmolipin |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables identical protein binding |
IDA
IDA: Inferred from direct assay
|
26002055 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| located in myelin sheath |
IDA
IDA: Inferred from direct assay
|
26002055 | GOA |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
26002055 | GOA |
PLLP Protein Structure
MARVEL: Membrane-associating domain (32 - 160)
- 0
- 100
- 182 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
plasmolipin |
|
PLLP Protein-protein interaction Information
|
Type
|
タンパク質名 | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | 参考文献 |
|---|---|---|---|---|---|---|---|
|
Intra
|
PLLP | Q9Y342 | MS4A12 | Homo sapiens | Q9NXJ0 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | MS4A12 | Homo sapiens | Q9NXJ0 | 25416956 | |
|
Intra
|
PLLP | Q9Y342 | MS4A12 | Homo sapiens | Q9NXJ0 | 25416956 | |
|
Intra
|
PLLP | Q9Y342 | MS4A12 | Homo sapiens | Q9NXJ0 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TRIM59 | Homo sapiens | Q8IWR1 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TRIM59 | Homo sapiens | Q8IWR1 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMEM174 | Homo sapiens | Q8WUU8 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMEM174 | Homo sapiens | Q8WUU8 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | PGRMC2 | Homo sapiens | O15173 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | PGRMC2 | Homo sapiens | O15173 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | VMA21 | Homo sapiens | Q3ZAQ7 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | VMA21 | Homo sapiens | Q3ZAQ7 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMPPE | Homo sapiens | Q6ZT21 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMPPE | Homo sapiens | Q6ZT21 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CLDN14 | Homo sapiens | O95500 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CLDN14 | Homo sapiens | O95500 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CLEC2D | Homo sapiens | Q9UHP7-3 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CLEC2D | Homo sapiens | Q9UHP7-3 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | KCNJ6 | Homo sapiens | P48051 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | KCNJ6 | Homo sapiens | P48051 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | FNDC9 | Homo sapiens | Q8TBE3 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | FNDC9 | Homo sapiens | Q8TBE3 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CLEC12B | Homo sapiens | Q2HXU8-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CLEC12B | Homo sapiens | Q2HXU8-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | ZDHHC15 | Homo sapiens | Q96MV8 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | ZDHHC15 | Homo sapiens | Q96MV8 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CD164L2 | Homo sapiens | Q6UWJ8-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CD164L2 | Homo sapiens | Q6UWJ8-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | GOLT1A | Homo sapiens | Q6ZVE7 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | GOLT1A | Homo sapiens | Q6ZVE7 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CRB3 | Homo sapiens | Q9BUF7-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CRB3 | Homo sapiens | Q9BUF7-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMEM167B | Homo sapiens | Q9NRX6 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMEM167B | Homo sapiens | Q9NRX6 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | SYPL2 | Homo sapiens | Q5VXT5-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | SYPL2 | Homo sapiens | Q5VXT5-2 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | FAM174A | Homo sapiens | Q8TBP5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | FAM174A | Homo sapiens | Q8TBP5 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | RNF122 | Homo sapiens | Q9H9V4 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | RNF122 | Homo sapiens | Q9H9V4 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | STING1 | Homo sapiens | Q86WV6 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | STING1 | Homo sapiens | Q86WV6 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | LHFPL5 | Homo sapiens | Q8TAF8 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | LHFPL5 | Homo sapiens | Q8TAF8 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | SAR1A | Homo sapiens | Q9NR31 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | SAR1A | Homo sapiens | Q9NR31 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TIGIT | Homo sapiens | Q495A1 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TIGIT | Homo sapiens | Q495A1 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | PACC1 | Homo sapiens | Q9H813 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | PACC1 | Homo sapiens | Q9H813 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TNFSF14 | Homo sapiens | O43557 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TNFSF14 | Homo sapiens | O43557 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | BCL2L13 | Homo sapiens | Q9BXK5 | 25416956 | |
|
Intra
|
PLLP | Q9Y342 | BCL2L13 | Homo sapiens | Q9BXK5 | 25416956 | |
|
Intra
|
PLLP | Q9Y342 | BCL2L13 | Homo sapiens | Q9BXK5 | 25416956 | |
|
Intra
|
PLLP | Q9Y342 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 | |
|
Intra
|
PLLP | Q9Y342 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Usher Syndrome, Type Iiia |
|
|
| Schizophrenia |
|
|
| Bardet-Biedl Syndrome |
|
|
| Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive |
|
|
Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Bos taurus | PLLP | VGNC | VGNC:33037 |
| Canis familiaris | PLLP | VGNC | VGNC:44699 |
| Rattus norvegicus | PLLP | RGD | RGD:621478 |
| Mus musculus | PLLP | MGD | MGI:1915051 |
| Macaca mulatta | PLLP | VGNC | VGNC:99579 |
| Others | PLLP | NCBI |