SLC10A6 - solute carrier family 10 member 6 Gene
Also Known as SOAT
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 345274
About SLC10A6
Cytogenetic location: 4q21.3
Genomic coordinates (GRCh38): 4:86,823,468-86,849,384 (from NCBI)
This gene has 2 transcripts (splice variants), 121 orthologues and 5 paralogues. Biased expression in skin (RPKM 6.2), esophagus (RPKM 5.0) and 7 other tissues.
Summary
Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
SLC10A6 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_197965.3 | NP_932069.1 | sodium-dependent organic anion transporter |
SLC10A6 Protein Structure
SBF
SBF: Sodium Bile acid symporter family (39 - 211)
- 0
- 100
- 200
- 300
- 377 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sodium-dependent organic anion transporter |
|
SLC10A6 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
SLC10A6 | Q3KNW5 | RTP2 | Homo sapiens | Q5QGT7 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | NRM | Homo sapiens | Q8IXM6 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC25A46 | Homo sapiens | Q96AG3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC30A3 | Homo sapiens | Q99726 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM242 | Homo sapiens | Q9NWH2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | NINJ2 | Homo sapiens | Q9NZG7 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SERP1 | Homo sapiens | Q9Y6X1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | ORMDL1 | Homo sapiens | Q9P0S3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM128 | Homo sapiens | Q5BJH2-2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | FA2H | Homo sapiens | Q7L5A8 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TVP23B | Homo sapiens | Q9NYZ1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | CMTM5 | Homo sapiens | Q96DZ9-2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM239 | Homo sapiens | Q8WW34-2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | ARV1 | Homo sapiens | Q9H2C2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | GPR151 | Homo sapiens | Q8TDV0 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SNORC | Homo sapiens | Q6UX34 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | CLDND2 | Homo sapiens | Q8NHS1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | GIMAP1 | Homo sapiens | Q8WWP7 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM86A | Homo sapiens | Q8N2M4 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | LPAR3 | Homo sapiens | Q9UBY5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | ATP13A1 | Homo sapiens | Q9HD20-3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | ANKRD46 | Homo sapiens | Q86W74-2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | FAXDC2 | Homo sapiens | Q96IV6 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM229B | Homo sapiens | Q8NBD8 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TSPO2 | Homo sapiens | Q5TGU0 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC41A1 | Homo sapiens | Q8IVJ1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM203 | Homo sapiens | Q969S6 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | DGAT2L6 | Homo sapiens | Q6ZPD8 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | ZDHHC15 | Homo sapiens | Q96MV8 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM107 | Homo sapiens | Q6UX40 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC12A7 | Homo sapiens | Q9Y666-2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM208 | Homo sapiens | Q9BTX3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | HTATIP2 | Homo sapiens | Q9BUP3-3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | RNF24 | Homo sapiens | Q9Y225-2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | CDS1 | Homo sapiens | Q92903 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM143 | Homo sapiens | Q96AN5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TREX1 | Homo sapiens | Q9NSU2-1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TPRG1 | Homo sapiens | Q6ZUI0 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC35C2 | Homo sapiens | Q9NQQ7-3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | OR7D4 | Homo sapiens | Q8NG98 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM14C | Homo sapiens | Q9P0S9 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM86B | Homo sapiens | Q8N661 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | STX12 | Homo sapiens | Q86Y82 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SCAMP5 | Homo sapiens | Q8TAC9 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM14A | Homo sapiens | Q9Y6G1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | OSMR | Homo sapiens | Q99650 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | EMC6 | Homo sapiens | Q9BV81 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | PIP4P2 | Homo sapiens | Q8N4L2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC39A9 | Homo sapiens | Q9NUM3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | COX20 | Homo sapiens | Q5RI15 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | C11orf24 | Homo sapiens | Q96F05 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM60 | Homo sapiens | Q9H2L4 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | q96fb2_human | Homo sapiens | Q96FB2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | MFSD6 | Homo sapiens | Q6ZSS7 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | NAT8 | Homo sapiens | Q9UHE5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | CCL4 | Homo sapiens | P13236 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | FAM3C | Homo sapiens | Q92520 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | FAM3C | Homo sapiens | Q92520 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | ACSL5 | Homo sapiens | Q9ULC5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TECR | Homo sapiens | Q9NZ01 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | FIS1 | Homo sapiens | Q9Y3D6 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SFXN1 | Homo sapiens | Q9H9B4 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | COMT | Homo sapiens | P21964 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC66A2 | Homo sapiens | Q8N2U9 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SACM1L | Homo sapiens | Q9NTJ5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | PLLP | Homo sapiens | Q9Y342 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | MFSD5 | Homo sapiens | Q6N075 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | DERL1 | Homo sapiens | Q9BUN8 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | GOLT1B | Homo sapiens | Q9Y3E0 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SCAMP4 | Homo sapiens | Q969E2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | PIP4P1 | Homo sapiens | Q86T03 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM65 | Homo sapiens | Q6PI78 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | ERG28 | Homo sapiens | Q9UKR5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | FXYD6 | Homo sapiens | Q9H0Q3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | FUNDC2 | Homo sapiens | Q9BWH2 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | NEU1 | Homo sapiens | Q99519 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | PRRT2 | Homo sapiens | Q7Z6L0 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | STX8 | Homo sapiens | Q9UNK0 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC35G2 | Homo sapiens | Q8TBE7 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | STATH | Homo sapiens | P02808 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SERP2 | Homo sapiens | Q8N6R1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | YIPF2 | Homo sapiens | Q9BWQ6 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | YIPF6 | Homo sapiens | Q96EC8 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | UNC50 | Homo sapiens | Q53HI1 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | YIPF1 | Homo sapiens | Q9Y548 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | RUSF1 | Homo sapiens | Q96GQ5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | RUSF1 | Homo sapiens | Q96GQ5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM234 | Homo sapiens | Q8WY98 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC30A2 | Homo sapiens | Q9BRI3 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | BTN2A2 | Homo sapiens | Q8WVV5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | TMEM252 | Homo sapiens | Q8N6L7 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | CCDC167 | Homo sapiens | Q9P0B6 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | PEX16 | Homo sapiens | Q9Y5Y5 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | UBE2J1 | Homo sapiens | Q9Y385 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | SLC38A1 | Homo sapiens | Q9H2H9 | 32296183 | |
|
Intra
|
SLC10A6 | Q3KNW5 | PSENEN | Homo sapiens | Q9NZ42 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(4)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-182542 | SOAT-IN-3 | Inhibitor | / | Unkown |
| HY-182767 | SOAT-IN-2 | Inhibitor | / | Unkown |
| HY-RS12992 | SLC10A6 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-168523 | S1647 | Inhibitor | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | SLC10A6 | MGD | MGI:1923000 |
| Canis familiaris | SLC10A6 | VGNC | VGNC:46214 |
| Macaca mulatta | SLC10A6 | VGNC | VGNC:77584 |
| Rattus norvegicus | SLC10A6 | RGD | RGD:727800 |
| Felis catus | SLC10A6 | VGNC | VGNC:65184 |
| Others | SLC10A6 | NCBI |
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