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51030

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By Targets:	Dopamine Receptor (1) Drug Derivative (1) EGFR (1) mAChR (1) MicroRNA (16) Opioid Receptor (2) Reference Standards (1) β-glucuronidase (1)
By Research Areas:	Cancer (17) Endocrinology (1) Inflammation/Immunology (1) Neurological Disease (4)
Oligonucleotides:	miRNA mimics (4) miRNA agomirs (4) miRNA antagomirs (4) MicroRNAs (16) miRNA inhibitors (4)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-104006

CYM51010	Opioid Receptor	Neurological Disease
CYM51010 is a biased ligand of μ-opioid receptor – δ-opioid receptor heterodimers with an EC₅₀ of 403 nM. CYM51010 exhibits anti-nociceptive activity similar to morphine but with a decreased levels of tolerance development and withdrawal symptoms .

HY-118363

Lu AE51090	mAChR	Neurological Disease
Lu AE51090 is selective muscarinic M1 receptor agonist with blood-brain barrier penetration. Lu AE51090 activates human M1 receptor with EC₅₀ of 61 nM, while showing no significant agonism at M2-M5 receptors. Lu AE51090 exerts procognitive effects in mice. Lu AE51090 can be used for the study of Alzheimer’s disease (AD) and cognitive impairment associated with schizophrenia (CIAS) .

HY-143319

SPH5030	EGFR	Cancer
SPH5030 is a selective and irreversible HER2 inhibitor. SPH5030 inhibits HER2 ^WT and EGFR ^WT with IC₅₀s of 3.51 and 8.13 nM, respectively. SPH5030 shows excellent activities against HER2 mutants. SPH5030 can be used for the research of cancer .

HY-N16039

*TAN-1030A*	β-glucuronidase	Inflammation/Immunology
TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice .

HY-106995

PD 172760 CI 1030	Dopamine Receptor	Neurological Disease
PD 172760 (CI 1030) is a selective D4 receptor antagonist. PD 172760 along with the action of other neurotransmitter receptors may be important in study psychosis .

HY-RI03248A

*mmu-miR-5103* antagomir**	MicroRNA	Cancer
mmu-miR-5103 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5103 antagomir mmu-miR-5103 antagomir

HY-160984

Rotraxate TEI 5103; TG 51	Drug Derivative	Endocrinology
Rotraxate (TEI 5103) is an orally active anti-ulcer compound. Rotraxate can increase blood flow to the gastric mucosa and promote the integrity of the gastric mucosa. Rotraxate can be used to study the protective effects of drugs on the gastric mucosa, especially in investigating how drugs can prevent or treat gastric ulcers by acting directly on the gastric mucosa .

HY-R01535A

*hsa-miR-5100* agomir**	MicroRNA	Cancer
hsa-miR-5100 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5100 agomir hsa-miR-5100 agomir

HY-R03246

*mmu-miR-5100* mimic**	MicroRNA	Cancer
mmu-miR-5100 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5100 mimic mmu-miR-5100 mimic

HY-RI03246A

*mmu-miR-5100* antagomir**	MicroRNA	Cancer
mmu-miR-5100 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5100 antagomir mmu-miR-5100 antagomir

HY-R01535

*hsa-miR-5100* mimic**	MicroRNA	Cancer
hsa-miR-5100 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5100 mimic hsa-miR-5100 mimic

HY-R03276

*mmu-miR-5130* mimic**	MicroRNA	Cancer
mmu-miR-5130 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5130 mimic mmu-miR-5130 mimic

HY-104006R

CYM51010 (Standard)	Reference Standards Opioid Receptor	Neurological Disease
CYM51010 (Standard) is the analytical standard of CYM51010 (HY-104006). This product is intended for research and analytical applications. CYM51010 is a biased ligand of μ-opioid receptor – δ-opioid receptor heterodimers with an EC₅₀ of 403 nM. CYM51010 exhibits anti-nociceptive activity similar to morphine but with a decreased levels of tolerance development and withdrawal symptoms .

HY-RI03248

*mmu-miR-5103* inhibitor**	MicroRNA	Cancer
mmu-miR-5103 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5103 inhibitor mmu-miR-5103 inhibitor

HY-RI01535A

*hsa-miR-5100* antagomir**	MicroRNA	Cancer
hsa-miR-5100 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5100 antagomir hsa-miR-5100 antagomir

HY-R03248A

*mmu-miR-5103* agomir**	MicroRNA	Cancer
mmu-miR-5103 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5103 agomir mmu-miR-5103 agomir

HY-RI03246

*mmu-miR-5100* inhibitor**	MicroRNA	Cancer
mmu-miR-5100 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5100 inhibitor mmu-miR-5100 inhibitor

HY-R03248

*mmu-miR-5103* mimic**	MicroRNA	Cancer
mmu-miR-5103 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5103 mimic mmu-miR-5103 mimic

HY-RI03276A

*mmu-miR-5130* antagomir**	MicroRNA	Cancer
mmu-miR-5130 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5130 antagomir mmu-miR-5130 antagomir

HY-RI01535

*hsa-miR-5100* inhibitor**	MicroRNA	Cancer
hsa-miR-5100 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5100 inhibitor hsa-miR-5100 inhibitor

HY-R03246A

*mmu-miR-5100* agomir**	MicroRNA	Cancer
mmu-miR-5100 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5100 agomir mmu-miR-5100 agomir

HY-RI03276

*mmu-miR-5130* inhibitor**	MicroRNA	Cancer
mmu-miR-5130 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5130 inhibitor mmu-miR-5130 inhibitor

HY-R03276A

*mmu-miR-5130* agomir**	MicroRNA	Cancer
mmu-miR-5130 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5130 agomir mmu-miR-5130 agomir

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16039

*TAN-1030A*	Alkaloids Microorganisms Indole Alkaloids Source Classification	β-glucuronidase
TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice .

Host:	Mouse (4) Rabbit (3)
Reactivity:	Human (7) Mouse (3) Dog (1)
Application:	IHC-P (3) ICC/IF (1) IF-Tissue (1) IP (2) IHC-F (1) WB (4) FC (1) ELISA (1)
Isotype:	IgG (4) IgG1 (2)
Conjugation:	Non-conjugated (7)
Clonality:	Monoclonal (5) Recombinant (2)
Modification:	Phosphorylated (1) Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88973

	ZNF583 Antibody (YA8657) FLJ31030; MGC133237	IHC-P	Human
	ZNF583 Antibody (YA8657) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZNF583.

HY-P88973A

	ZNF583 Antibody (YA8657)(PBS only) FLJ31030; MGC133237	IHC-P	Human
	ZNF583 Antibody (YA8657) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZNF583.

HY-P85411

	Wnt5a Antibody (YA5103) WNT5A; Protein Wnt-5a	WB, ICC/IF, FC	Human
	Wnt5a Antibody (YA5103) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Wnt5a.

HY-P81301A

	Phospho-Rb (Ser780) Antibody (YA1030) RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110	WB, IP	Human, Mouse
	Phospho-Rb (Ser780) Antibody (YA1030) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Rb (Ser780).

HY-P81301AA

	Phospho-Rb (Ser780) Antibody (YA1030)(PBS only) RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110	WB, IP	Human, Mouse
	Phospho-Rb (Ser780) Antibody (YA1030) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-Rb (Ser780).

HY-P85338

	Prostate Specific Antigen Antibody (YA5030) KLK3; APS; Prostate-specific antigen; PSA; Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase	IHC-P, IHC-F, IF-Tissue, ELISA	Human
	Prostate Specific Antigen Antibody (YA5030) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Prostate Specific Antigen.

HY-P85438

	Ikaros Antibody (YA5130) IKZF1; IK1; IKAROS; LYF1; ZNFN1A1; DNA-binding protein Ikaros; Ikaros family zinc finger protein 1; Lymphoid transcription factor LyF-1	WB	Human, Mouse, Dog
	Ikaros Antibody (YA5130) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Ikaros.

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Cat. No.	Product Name		Classification

HY-RI03248A

*mmu-miR-5103* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5103 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01535A

*hsa-miR-5100* agomir**		MicroRNAs miRNA agomirs
hsa-miR-5100 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03246

*mmu-miR-5100* mimic**		MicroRNAs miRNA mimics
mmu-miR-5100 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03246A

*mmu-miR-5100* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5100 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01535

*hsa-miR-5100* mimic**		MicroRNAs miRNA mimics
hsa-miR-5100 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03276

*mmu-miR-5130* mimic**		MicroRNAs miRNA mimics
mmu-miR-5130 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03248

*mmu-miR-5103* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5103 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01535A

*hsa-miR-5100* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-5100 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03248A

*mmu-miR-5103* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5103 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03246

*mmu-miR-5100* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5100 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03248

*mmu-miR-5103* mimic**		MicroRNAs miRNA mimics
mmu-miR-5103 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03276A

*mmu-miR-5130* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5130 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01535

*hsa-miR-5100* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-5100 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03246A

*mmu-miR-5100* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5100 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03276

*mmu-miR-5130* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5130 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03276A

*mmu-miR-5130* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5130 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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51030

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