TLCD4 - TLC domain containing 4 Gene

Also Known as TMEM56

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 148534

Summary

Predicted to be involved in lipid homeostasis. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Jul 2025]
Broad expression in liver (RPKM 27.2), heart (RPKM 9.3) and 19 other tissues.

TLCD4 Products (2)

mRNA Protein Name
NM_001199679.2 NP_001186608.1 TLC domain-containing protein 4
NM_152487.3 NP_689700.1 TLC domain-containing protein 4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TLCD4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TLCD4 Q96MV1 SERP1 Homo sapiens Q9Y6X1
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 ORMDL1 Homo sapiens Q9P0S3
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 ADGRE2 Homo sapiens Q9UHX3
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 TVP23B Homo sapiens Q9NYZ1
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 ARV1 Homo sapiens Q9H2C2
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 CLEC7A Homo sapiens Q9BXN2-6
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 CLEC7A Homo sapiens Q9BXN2-6
Y2H Array
32296183
Intra
TLCD4 Q96MV1 CLEC7A Homo sapiens Q9BXN2-6
Y2H Prey Pooling
32296183
Intra
TLCD4 Q96MV1 ATP13A1 Homo sapiens Q9HD20-3
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 LNPEP Homo sapiens Q9UIQ6-2
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 EMC6 Homo sapiens Q9BV81
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 NAT8 Homo sapiens Q9UHE5
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 SFXN1 Homo sapiens Q9H9B4
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 MYG1 Homo sapiens Q9HB07
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 MYG1 Homo sapiens Q9HB07
Y2H Prey Pooling
32296183
Intra
TLCD4 Q96MV1 MYG1 Homo sapiens Q9HB07
Y2H Array
32296183
Intra
TLCD4 Q96MV1 ERG28 Homo sapiens Q9UKR5
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 FXYD6 Homo sapiens Q9H0Q3
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 FXYD6 Homo sapiens Q9H0Q3
Y2H Array
32296183
Intra
TLCD4 Q96MV1 SYNDIG1 Homo sapiens Q9H7V2
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 YIPF4 Homo sapiens Q9BSR8
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 YIPF1 Homo sapiens Q9Y548
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 CCDC167 Homo sapiens Q9P0B6
Validated Y2H
32296183
Intra
TLCD4 Q96MV1 UBE2J1 Homo sapiens Q9Y385
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-176431 TLCD1-IN-1 / Unkown
HY-RS10658 PLCD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14561 TLCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14562 TLCD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown