2. Gene
  3. UBE2J1 - ubiquitin conjugating enzyme E2 J1 Gene

UBE2J1 - ubiquitin conjugating enzyme E2 J1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as UBC6; UBC6E; Ubc6p; CGI-76; NCUBE1; HSPC153; HSPC205; NCUBE-1; HSU93243

Gene ID: 51465 | Gene type: protein coding

About UBE2J1

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,326,625-89,352,722 (from NCBI)

This gene has 1 transcript (splice variant), 209 orthologues and 24 paralogues. Ubiquitous expression in lymph node (RPKM 49.6), bone marrow (RPKM 46.1) and 25 other tissues.

Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating Enzyme family. This Enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]

UBE2J1 Products(1)

mRNA Protein Name
NM_016021.3 NP_057105.2 ubiquitin-conjugating enzyme E2 J1

UBE2J1 Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (14 - 121)

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  • 318 a.a.
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 J1

E2 ubiquitin-conjugating enzyme J1

Related Diseases

Diseases Alias
Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15350 UBE2J1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus UBE2J1 MGD MGI:1926245
Canis familiaris UBE2J1 VGNC VGNC:48055
Rattus norvegicus UBE2J1 RGD RGD:1305067
Felis catus UBE2J1 VGNC VGNC:66760
Macaca mulatta UBE2J1 VGNC VGNC:83963
Bos taurus UBE2J1 VGNC VGNC:36585
Others UBE2J1 NCBI