2. Gene
  3. SLC39A2 - solute carrier family 39 member 2 Gene

SLC39A2 - solute carrier family 39 member 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as 6A1; ZIP2; ETI-1; ZIP-2

Gene ID: 29986 | Gene type: protein coding

About SLC39A2

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:20,999,293-21,001,871 (from NCBI)

This gene has 3 transcripts (splice variants), 121 orthologues and 2 paralogues. Biased expression in skin (RPKM 12.0), esophagus (RPKM 8.3) and 3 other tissues.

Summary

This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple transcript variants have been described. [provided by RefSeq, Mar 2010]

SLC39A2 Products(2)

mRNA Protein Name
NM_001256588.2 NP_001243517.1 zinc transporter ZIP2 isoform b
NM_014579.4 NP_055394.2 zinc transporter ZIP2 isoform a

SLC39A2 Protein Structure

Zip

Zip: ZIP Zinc transporter (6 - 306)

  • 0
  • 100
  • 200
  • 309 a.a.
Protein Preferred Names Protein Names

zinc transporter ZIP2

ZRT/IRT-like protein 2

Related Diseases

Diseases Alias
Carotid Artery Disease

Carotid Artery Diseases

Disorder Of Carotid Artery
Acrodermatitis Enteropathica, Zinc-Deficiency Type

Acrodermatitis Enteropathica

AEZ

Enteropathica

Brandt Syndrome

Ae

Acrodermatitis Enteropathica Zinc Deficiency Type

Danbolt-Cross Syndrome

Acrodermatitis Enteropathica, Zinc Deficiency Type

Inherited Zinc Deficiency

Acrodermatitis Enteropathica, Zinc Deficiency

Danbolt-Closs Syndrome

Primary Zinc Malabsorption Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13234 SLC39A2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SLC39A2 MGD MGI:2684326
Rattus norvegicus SLC39A2 RGD RGD:1306291
Bos taurus SLC39A2 VGNC VGNC:34863
Canis familiaris SLC39A2 VGNC VGNC:46403
Felis catus SLC39A2 VGNC VGNC:65359