GPR42 - G protein-coupled receptor 42 Gene
Also Known as FFAR1L; FFAR3L; GPR41L; GPR42P
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 2866
About GPR42
Cytogenetic location: 19q13.12
Genomic coordinates (GRCh38): 19:35,371,068-35,372,962 (from NCBI)
This gene has 2 transcripts (splice variants), 339 orthologues and 15 paralogues.
Summary
Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
GPR42 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001348195.2 | NP_001335124.1 | G-protein coupled receptor 42 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| NOT enables G protein-coupled receptor activity |
IDA
IDA: Inferred from direct assay
|
12496283 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| NOT involved in G protein-coupled receptor signaling pathway |
IDA
IDA: Inferred from direct assay
|
12496283 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
GPR42 Protein Structure
7tm_1
7tm_1: 7 transmembrane receptor (rhodopsin family) (32 - 276)
- 0
- 100
- 200
- 300
- 346 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
G-protein coupled receptor 42 |
|
GPR42 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
GPR42 | O15529 | RTP2 | Homo sapiens | Q5QGT7 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM182 | Homo sapiens | Q6ZP80 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC30A8 | Homo sapiens | Q8IWU4 | 32296183 | |
|
Intra
|
GPR42 | O15529 | NRM | Homo sapiens | Q8IXM6 | 32296183 | |
|
Intra
|
GPR42 | O15529 | NRM | Homo sapiens | Q8IXM6 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CCL4L1 | Homo sapiens | Q8NHW4 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC41A2 | Homo sapiens | Q96JW4 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC30A3 | Homo sapiens | Q99726 | 32296183 | |
|
Intra
|
GPR42 | O15529 | DRAM1 | Homo sapiens | Q8N682 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC38A7 | Homo sapiens | Q9NVC3 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM242 | Homo sapiens | Q9NWH2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | NINJ2 | Homo sapiens | Q9NZG7 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TEX264 | Homo sapiens | Q9Y6I9 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMBIM6 | Homo sapiens | P55061 | 32296183 | |
|
Intra
|
GPR42 | O15529 | RPRM | Homo sapiens | Q9NS64 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ADIPOQ | Homo sapiens | Q15848 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ERMP1 | Homo sapiens | Q7Z2K6 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM239 | Homo sapiens | Q8WW34-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CLEC2D | Homo sapiens | Q9UHP7-3 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CTXN3 | Homo sapiens | Q4LDR2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ATP13A1 | Homo sapiens | Q9HD20-3 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ANKRD46 | Homo sapiens | Q86W74-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | LNPEP | Homo sapiens | Q9UIQ6-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | FXYD3 | Homo sapiens | Q14802-3 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SYNGR1 | Homo sapiens | O43759-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | PLP1 | Homo sapiens | P60201-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | PLP1 | Homo sapiens | P60201-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TSPO2 | Homo sapiens | Q5TGU0 | 32296183 | |
|
Intra
|
GPR42 | O15529 | STRIT1 | Homo sapiens | P0DN84 | 32296183 | |
|
Intra
|
GPR42 | O15529 | LTC4S | Homo sapiens | Q16873 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC41A1 | Homo sapiens | Q8IVJ1 | 32296183 | |
|
Intra
|
GPR42 | O15529 | NDUFB11 | Homo sapiens | Q9NX14 | 32296183 | |
|
Intra
|
GPR42 | O15529 | IL1RL1 | Homo sapiens | Q01638-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC35E4 | Homo sapiens | Q6ICL7 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC39A2 | Homo sapiens | Q9NP94 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TREX1 | Homo sapiens | Q9NSU2-1 | 32296183 | |
|
Intra
|
GPR42 | O15529 | EFNA5 | Homo sapiens | P52803 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ITGAM | Homo sapiens | P11215 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SERINC1 | Homo sapiens | Q9NRX5 | 32296183 | |
|
Intra
|
GPR42 | O15529 | YIF1A | Homo sapiens | O95070 | 32296183 | |
|
Intra
|
GPR42 | O15529 | MS4A1 | Homo sapiens | P11836 | 32296183 | |
|
Intra
|
GPR42 | O15529 | LHFPL5 | Homo sapiens | Q8TAF8 | 32296183 | |
|
Intra
|
GPR42 | O15529 | MGAM | Homo sapiens | O43451 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM140 | Homo sapiens | Q9NV12 | 32296183 | |
|
Intra
|
GPR42 | O15529 | PMP22 | Homo sapiens | Q01453 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM60 | Homo sapiens | Q9H2L4 | 32296183 | |
|
Intra
|
GPR42 | O15529 | MFSD6 | Homo sapiens | Q6ZSS7 | 32296183 | |
|
Intra
|
GPR42 | O15529 | FAM3C | Homo sapiens | Q92520 | 32296183 | |
|
Intra
|
GPR42 | O15529 | GPR37L1 | Homo sapiens | O60883 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM147 | Homo sapiens | Q9BVK8 | 32296183 | |
|
Intra
|
GPR42 | O15529 | COMT | Homo sapiens | P21964 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ATP6V0B | Homo sapiens | Q99437 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ATP4B | Homo sapiens | P51164 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ALOX5AP | Homo sapiens | P20292 | 32296183 | |
|
Intra
|
GPR42 | O15529 | GJB2 | Homo sapiens | P29033 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CXCL9 | Homo sapiens | Q07325 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CD300C | Homo sapiens | Q08708 | 32296183 | |
|
Intra
|
GPR42 | O15529 | MFSD5 | Homo sapiens | Q6N075 | 32296183 | |
|
Intra
|
GPR42 | O15529 | EMP1 | Homo sapiens | P54849 | 32296183 | |
|
Intra
|
GPR42 | O15529 | JPH1 | Homo sapiens | Q9HDC5 | 32296183 | |
|
Intra
|
GPR42 | O15529 | PAEP | Homo sapiens | P09466 | 32296183 | |
|
Intra
|
GPR42 | O15529 | NSG1 | Homo sapiens | P42857 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM65 | Homo sapiens | Q6PI78 | 32296183 | |
|
Intra
|
GPR42 | O15529 | FXYD6 | Homo sapiens | Q9H0Q3 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TF | Homo sapiens | P02787 | 32296183 | |
|
Intra
|
GPR42 | O15529 | APOD | Homo sapiens | P05090 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ZFPL1 | Homo sapiens | O95159 | 32296183 | |
|
Intra
|
GPR42 | O15529 | IGFBP5 | Homo sapiens | P24593 | 32296183 | |
|
Intra
|
GPR42 | O15529 | ATP6V0C | Homo sapiens | P27449 | 32296183 | |
|
Intra
|
GPR42 | O15529 | IER3IP1 | Homo sapiens | Q9Y5U9 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SYNDIG1 | Homo sapiens | Q9H7V2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | STX8 | Homo sapiens | Q9UNK0 | 32296183 | |
|
Intra
|
GPR42 | O15529 | STATH | Homo sapiens | P02808 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM19 | Homo sapiens | Q96HH6 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SMIM3 | Homo sapiens | Q9BZL3 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SERP2 | Homo sapiens | Q8N6R1 | 32296183 | |
|
Intra
|
GPR42 | O15529 | BNIP3 | Homo sapiens | Q12983 | 32296183 | |
|
Intra
|
GPR42 | O15529 | KLRG1 | Homo sapiens | Q96E93 | 32296183 | |
|
Intra
|
GPR42 | O15529 | LEPROTL1 | Homo sapiens | O95214 | 32296183 | |
|
Intra
|
GPR42 | O15529 | YIPF2 | Homo sapiens | Q9BWQ6 | 32296183 | |
|
Intra
|
GPR42 | O15529 | YIPF6 | Homo sapiens | Q96EC8 | 32296183 | |
|
Intra
|
GPR42 | O15529 | YIPF4 | Homo sapiens | Q9BSR8 | 32296183 | |
|
Intra
|
GPR42 | O15529 | GYPC | Homo sapiens | P04921 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
GPR42 | O15529 | YIPF1 | Homo sapiens | Q9Y548 | 32296183 | |
|
Intra
|
GPR42 | O15529 | LAT | Homo sapiens | O43561-2 | 32296183 | |
|
Intra
|
GPR42 | O15529 | KCNA1 | Homo sapiens | Q09470 | 32296183 | |
|
Intra
|
GPR42 | O15529 | RUSF1 | Homo sapiens | Q96GQ5 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SMCO4 | Homo sapiens | Q9NRQ5 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC30A2 | Homo sapiens | Q9BRI3 | 32296183 | |
|
Intra
|
GPR42 | O15529 | BTN2A2 | Homo sapiens | Q8WVV5 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TM4SF4 | Homo sapiens | P48230 | 32296183 | |
|
Intra
|
GPR42 | O15529 | PNLIPRP1 | Homo sapiens | P54315 | 32296183 | |
|
Intra
|
GPR42 | O15529 | CCDC167 | Homo sapiens | Q9P0B6 | 32296183 | |
|
Intra
|
GPR42 | O15529 | TMEM30B | Homo sapiens | Q3MIR4 | 32296183 | |
|
Intra
|
GPR42 | O15529 | SLC38A1 | Homo sapiens | Q9H2H9 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS04876 | FFAR3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05715 | GPR42 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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