SLC38A7 - solute carrier family 38 member 7 Gene

Also Known as SNAT7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55238

About SLC38A7

Cytogenetic location: 16q21 Genomic coordinates (GRCh38): 16:58,665,109-58,684,770 (from NCBI)

This gene has 16 transcripts (splice variants), 242 orthologues and 15 paralogues. Broad expression in testis (RPKM 12.2), brain (RPKM 4.6) and 23 other tissues.

Summary

Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport and sodium ion transport. Predicted to be located in axon and neuronal cell body. [provided by Alliance of Genome Resources, Apr 2022]

SLC38A7 Products (6)

mRNA Protein Name
NM_001308384.2 NP_001295313.1 putative sodium-coupled neutral amino acid transporter 7 isoform 2
NM_001369608.1 NP_001356537.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1
NM_001369609.1 NP_001356538.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1
NM_001369610.1 NP_001356539.1 putative sodium-coupled neutral amino acid transporter 7 isoform 2
NM_001369611.1 NP_001356540.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1
NM_018231.3 NP_060701.1 putative sodium-coupled neutral amino acid transporter 7 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-asparagine:sodium symporter activity IDA
IDA: Inferred from direct assay
28416685 GOA
enables L-glutamine:sodium symporter activity IDA
IDA: Inferred from direct assay
28416685 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in asparagine transport IDA
IDA: Inferred from direct assay
28416685 GOA
involved in glutamine transport IDA
IDA: Inferred from direct assay
28416685 GOA
Cellular Component GO Annotation Evidence References Source
located in lysosomal membrane IDA
IDA: Inferred from direct assay
35561222 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC38A7 Protein Structure

Aa_trans

Aa_trans: Transmembrane amino acid transporter protein (50 - 446)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 462 a.a.
Protein Preferred Names Protein Names

putative sodium-coupled neutral amino acid transporter 7

  • Sodium-coupled neutral amino acid transporter 7

SLC38A7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SLC38A7 Q9NVC3 IL10RA Homo sapiens Q13651
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 IL10RA Homo sapiens Q13651
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 LYVE1 Homo sapiens Q9Y5Y7
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 LYVE1 Homo sapiens Q9Y5Y7
Validated Y2H
32296183
Intra
SLC38A7 Q9NVC3 LYVE1 Homo sapiens Q9Y5Y7
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 ACBD5 Homo sapiens Q5T8D3-2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 ACBD5 Homo sapiens Q5T8D3-2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SLC6A15 Homo sapiens Q9H2J7
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SLC6A15 Homo sapiens Q9H2J7
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SPINT1 Homo sapiens O43278-2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SPINT1 Homo sapiens O43278-2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 ODF4 Homo sapiens Q2M2E3
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 ODF4 Homo sapiens Q2M2E3
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 AQP2 Homo sapiens P41181
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 AQP2 Homo sapiens P41181
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
Intra
SLC38A7 Q9NVC3 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 AQP9 Homo sapiens O43315
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 AQP9 Homo sapiens O43315
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SLC18A1 Homo sapiens P54219-3
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SLC18A1 Homo sapiens P54219-3
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 EVI2B Homo sapiens P34910-2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 EVI2B Homo sapiens P34910-2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 BTNL9 Homo sapiens Q6UXG8-3
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 BTNL9 Homo sapiens Q6UXG8-3
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SHISAL1 Homo sapiens Q3SXP7
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SHISAL1 Homo sapiens Q3SXP7
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SYPL2 Homo sapiens Q5VXT5-2
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SYPL2 Homo sapiens Q5VXT5-2
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 AMIGO1 Homo sapiens Q86WK6
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 AMIGO1 Homo sapiens Q86WK6
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 APH1A Homo sapiens Q96BI3
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 APH1A Homo sapiens Q96BI3
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 HHLA2 Homo sapiens Q9UM44
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 HHLA2 Homo sapiens Q9UM44
Validated Y2H
32296183
Intra
SLC38A7 Q9NVC3 HHLA2 Homo sapiens Q9UM44
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 CLEC10A Homo sapiens Q8IUN9
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 CLEC10A Homo sapiens Q8IUN9
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Array
25416956
Intra
SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 RNF5 Homo sapiens Q99942
Y2H Prey Pooling
25416956
Intra
SLC38A7 Q9NVC3 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 GJB5 Homo sapiens O95377
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 FKBP7 Homo sapiens Q9Y680
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 FKBP7 Homo sapiens Q9Y680
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 FKBP7 Homo sapiens Q9Y680
Validated Y2H
32296183
Intra
SLC38A7 Q9NVC3 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 TSPAN8 Homo sapiens P19075
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 TSPAN8 Homo sapiens P19075
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 EDA Homo sapiens Q92838
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 EDA Homo sapiens Q92838
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 MMGT1 Homo sapiens Q8N4V1
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 MMGT1 Homo sapiens Q8N4V1
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 PANX1 Homo sapiens Q96RD7
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 PANX1 Homo sapiens Q96RD7
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 CLDN7 Homo sapiens O95471
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 YIPF6 Homo sapiens Q96EC8
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 YIPF6 Homo sapiens Q96EC8
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra
SLC38A7 Q9NVC3 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 CREB3L3 Homo sapiens Q68CJ9
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 CREB3L3 Homo sapiens Q68CJ9
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 KIR2DL3 Homo sapiens P43628
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 KIR2DL3 Homo sapiens P43628
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 SLC30A2 Homo sapiens Q9BRI3
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 SLC30A2 Homo sapiens Q9BRI3
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 LY6G6C Homo sapiens O95867
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 LY6G6C Homo sapiens O95867
Y2H Array
32296183
Intra
SLC38A7 Q9NVC3 ERP29 Homo sapiens P30040
Y2H Prey Pooling
32296183
Intra
SLC38A7 Q9NVC3 ERP29 Homo sapiens P30040
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

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Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13225 SLC38A7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC38A7 VGNC VGNC:34854
Felis catus SLC38A7 VGNC VGNC:65350
Macaca mulatta SLC38A7 VGNC VGNC:77570
Mus musculus SLC38A7 MGD MGI:2679005
Rattus norvegicus SLC38A7 RGD RGD:1303268
Canis familiaris SLC38A7 VGNC VGNC:46397
Others SLC38A7 NCBI