TMEM52B - transmembrane protein 52B Gene

Also Known as C12orf59

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 120939

Summary

Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
Restricted expression toward kidney (RPKM 46.9).

TMEM52B Products (7)

mRNA Protein Name
NM_001079815.2 NP_001073283.1 transmembrane protein 52B isoform 2 precursor
NM_001384894.1 NP_001371823.1 transmembrane protein 52B isoform 2 precursor
NM_001384895.1 NP_001371824.1 transmembrane protein 52B isoform 2 precursor
NM_001384896.1 NP_001371825.1 transmembrane protein 52B isoform 2 precursor
NM_001384897.1 NP_001371826.1 transmembrane protein 52B isoform 3 precursor
NM_001384898.1 NP_001371827.1 transmembrane protein 52B isoform 1
NM_153022.4 NP_694567.1 transmembrane protein 52B isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM52B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM52B Q4KMG9 TTMP Homo sapiens Q5BVD1
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 RTP2 Homo sapiens Q5QGT7
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 SLC30A8 Homo sapiens Q8IWU4
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 NRM Homo sapiens Q8IXM6
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 JAGN1 Homo sapiens Q8N5M9
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 CSGALNACT2 Homo sapiens Q8N6G5
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 SLC35B4 Homo sapiens Q969S0
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 SLC38A7 Homo sapiens Q9NVC3
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 NINJ2 Homo sapiens Q9NZG7
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 MARCHF2 Homo sapiens Q9P0N8
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 SERP1 Homo sapiens Q9Y6X1
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 ORMDL1 Homo sapiens Q9P0S3
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM109 Homo sapiens Q9BVC6
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM128 Homo sapiens Q5BJH2-2
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TRAM1L1 Homo sapiens Q8N609
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 LPAR3 Homo sapiens Q9UBY5
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 MS4A13 Homo sapiens Q5J8X5
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 PGAP2 Homo sapiens Q9UHJ9-5
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM97 Homo sapiens Q5BJF2
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 CNIH3 Homo sapiens Q8TBE1
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 CLDN19 Homo sapiens Q8N6F1-2
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM203 Homo sapiens Q969S6
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 SLC35A4 Homo sapiens Q96G79
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 ZDHHC15 Homo sapiens Q96MV8
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM107 Homo sapiens Q6UX40
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM14C Homo sapiens Q9P0S9
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM86B Homo sapiens Q8N661
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMUB2 Homo sapiens Q71RG4
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 ALG3 Homo sapiens Q92685
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM147 Homo sapiens Q9BVK8
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM54 Homo sapiens Q969K7
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 APOL2 Homo sapiens Q9BQE5
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 INSIG2 Homo sapiens Q9Y5U4
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 DNAJC30 Homo sapiens Q96LL9
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 SLC30A2 Homo sapiens Q9BRI3
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 TMEM100 Homo sapiens Q9NV29
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 BTN2A2 Homo sapiens Q8WVV5
Validated Y2H
32296183
Intra
TMEM52B Q4KMG9 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14729 TMEM50B Human Pre-designed siRNA Set A Pre-designed Set / Unkown