TMEM54 - transmembrane protein 54 Gene

Also Known as BCLP; CAC1; CAC-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 113452

Summary

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Broad expression in colon (RPKM 134.2), small intestine (RPKM 52.7) and 15 other tissues.

TMEM54 Products (5)

mRNA Protein Name
NM_001329722.2 NP_001316651.1 transmembrane protein 54 isoform 1
NM_001329723.2 NP_001316652.1 transmembrane protein 54 isoform 3
NM_001329724.2 NP_001316653.1 transmembrane protein 54 isoform 4
NM_001329725.2 NP_001316654.1 transmembrane protein 54 isoform 5
NM_033504.4 NP_277039.1 transmembrane protein 54 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM54 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM54 Q969K7 CLSTN3 Homo sapiens Q9BQT9
Validated Y2H
32296183
Intra
TMEM54 Q969K7 CLSTN3 Homo sapiens Q9BQT9
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 CLSTN3 Homo sapiens Q9BQT9
Y2H Array
32296183
Intra
TMEM54 Q969K7 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
TMEM54 Q969K7 TSPO2 Homo sapiens Q5TGU0
Y2H Array
32296183
Intra
TMEM54 Q969K7 TSPO2 Homo sapiens Q5TGU0
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 UPK1B Homo sapiens O75841
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 UPK1B Homo sapiens O75841
Y2H Array
32296183
Intra
TMEM54 Q969K7 MS4A14 Homo sapiens Q96JA4
Validated Y2H
32296183
Intra
TMEM54 Q969K7 MS4A14 Homo sapiens Q96JA4
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 MS4A14 Homo sapiens Q96JA4
Y2H Array
32296183
Intra
TMEM54 Q969K7 NRG1 Homo sapiens Q02297-10
Y2H Array
32296183
Intra
TMEM54 Q969K7 NRG1 Homo sapiens Q02297-10
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 SLC12A7 Homo sapiens Q9Y666-2
Validated Y2H
32296183
Intra
TMEM54 Q969K7 SLC12A7 Homo sapiens Q9Y666-2
Y2H Array
32296183
Intra
TMEM54 Q969K7 SLC12A7 Homo sapiens Q9Y666-2
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 SLC39A2 Homo sapiens Q9NP94
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 SLC39A2 Homo sapiens Q9NP94
Validated Y2H
32296183
Intra
TMEM54 Q969K7 SLC39A2 Homo sapiens Q9NP94
Y2H Array
32296183
Intra
TMEM54 Q969K7 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra
TMEM54 Q969K7 KCNJ8 Homo sapiens Q15842
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 KCNJ8 Homo sapiens Q15842
Y2H Array
32296183
Intra
TMEM54 Q969K7 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra
TMEM54 Q969K7 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 GPR37L1 Homo sapiens O60883
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 GPR37L1 Homo sapiens O60883
Y2H Array
32296183
Intra
TMEM54 Q969K7 YWHAG Homo sapiens P61981
Y2H Pooling
32814053
Intra
TMEM54 Q969K7 YWHAG Homo sapiens P61981
Validated Y2H
32814053
Intra
TMEM54 Q969K7 YWHAG Homo sapiens P61981
Y2H Array
32814053
Intra
TMEM54 Q969K7 CD3G Homo sapiens P09693
Y2H Array
32296183
Intra
TMEM54 Q969K7 CD3G Homo sapiens P09693
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 FKBP7 Homo sapiens Q9Y680
Validated Y2H
32296183
Intra
TMEM54 Q969K7 FKBP7 Homo sapiens Q9Y680
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 FKBP7 Homo sapiens Q9Y680
Y2H Array
32296183
Intra
TMEM54 Q969K7 PVR Homo sapiens P15151
Y2H Array
32296183
Intra
TMEM54 Q969K7 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 KCNK5 Homo sapiens O95279
Y2H Array
32296183
Intra
TMEM54 Q969K7 KCNK5 Homo sapiens O95279
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 TIMMDC1 Homo sapiens Q9NPL8
Y2H Array
32296183
Intra
TMEM54 Q969K7 TIMMDC1 Homo sapiens Q9NPL8
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 TIMMDC1 Homo sapiens Q9NPL8
Validated Y2H
32296183
Intra
TMEM54 Q969K7 PRPH Homo sapiens P41219
Validated Y2H
32814053
Intra
TMEM54 Q969K7 PRPH Homo sapiens P41219
Y2H Array
32814053
Intra
TMEM54 Q969K7 PRPH Homo sapiens P41219
Y2H Pooling
32814053
Intra
TMEM54 Q969K7 KLRC1 Homo sapiens P26715
Y2H Prey Pooling
32296183
Intra
TMEM54 Q969K7 KLRC1 Homo sapiens P26715
Y2H Array
32296183
Intra
TMEM54 Q969K7 SETDB1 Homo sapiens Q15047-2
Validated Y2H
32814053
Intra
TMEM54 Q969K7 SETDB1 Homo sapiens Q15047-2
Y2H Array
32814053
Intra
TMEM54 Q969K7 SETDB1 Homo sapiens Q15047-2
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14673 TMEM154 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14725 TMEM44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14730 TMEM51 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14731 TMEM59 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14735 TMEM64 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14741 TMEM74 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14748 TMEM94 Human Pre-designed siRNA Set A Pre-designed Set / Unkown