TMUB2 - transmembrane and ubiquitin like domain containing 2 Gene

Also Known as FP2653

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79089

Summary

Predicted to be involved in ERAD pathway. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in testis (RPKM 16.4), spleen (RPKM 14.8) and 25 other tissues.

TMUB2 Products (22)

mRNA Protein Name
NM_001076674.3 NP_001070142.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform b
NM_001330235.2 NP_001317164.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform c
NM_001353173.2 NP_001340102.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353174.2 NP_001340103.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform c
NM_001353175.2 NP_001340104.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353176.2 NP_001340105.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353177.2 NP_001340106.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform b
NM_001353178.2 NP_001340107.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353180.2 NP_001340109.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform f
NM_001353181.2 NP_001340110.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform b
NM_001353182.2 NP_001340111.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353183.2 NP_001340112.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353184.2 NP_001340113.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform b
NM_001353185.2 NP_001340114.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform e
NM_001353186.2 NP_001340115.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform d
NM_001353187.2 NP_001340116.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform e
NM_001353188.2 NP_001340117.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353189.2 NP_001340118.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform f
NM_001353190.2 NP_001340119.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_001353191.2 NP_001340120.1 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_024107.4 NP_077012.2 transmembrane and ubiquitin-like domain-containing protein 2 isoform a
NM_177441.4 NP_803190.2 transmembrane and ubiquitin-like domain-containing protein 2 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMUB2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
TMUB2 Q71RG4 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Prey Pooling
25416956
Intra
TMUB2 Q71RG4 UBQLN1 Homo sapiens Q9UMX0-2
Validated Y2H
25416956
Intra
TMUB2 Q71RG4 IL10RA Homo sapiens Q13651
Y2H Array
32296183
Intra
TMUB2 Q71RG4 IL10RA Homo sapiens Q13651
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 NEMP1 Homo sapiens O14524-2
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 NEMP1 Homo sapiens O14524-2
Y2H Array
32296183
Intra
TMUB2 Q71RG4 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
TMUB2 Q71RG4 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
Intra
TMUB2 Q71RG4 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra
TMUB2 Q71RG4 MS4A4A Homo sapiens Q96JQ5
Y2H Array
32296183
Intra
TMUB2 Q71RG4 MS4A4A Homo sapiens Q96JQ5
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 MS4A4A Homo sapiens Q96JQ5
Validated Y2H
32296183
Intra
TMUB2 Q71RG4 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
TMUB2 Q71RG4 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra
TMUB2 Q71RG4 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra
TMUB2 Q71RG4 THSD7A Homo sapiens Q9UPZ6
Validated Y2H
32296183
Intra
TMUB2 Q71RG4 SGTA Homo sapiens O43765
Validated Y2H
25416956
Intra
TMUB2 Q71RG4 GJB3 Homo sapiens O75712
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 GJB3 Homo sapiens O75712
Y2H Array
32296183
Intra
TMUB2 Q71RG4 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra
TMUB2 Q71RG4 GOLM1 Homo sapiens Q8NBJ4
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 GOLM1 Homo sapiens Q8NBJ4
Y2H Array
32296183
Intra
TMUB2 Q71RG4 GOLM1 Homo sapiens Q8NBJ4
Validated Y2H
32296183
Intra
TMUB2 Q71RG4 BCL2L13 Homo sapiens Q9BXK5
Y2H Prey Pooling
25416956
Intra
TMUB2 Q71RG4 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra
TMUB2 Q71RG4 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra
TMUB2 Q71RG4 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant TMUB2 Proteins

Cat. No. Nom du produit Accession Pureté
HY-P77251 TMUB2 Protein, Human (HEK293, His) Q71RG4-2/NP_803190.2 (Y37-S245) ≥ 95%, as determined by reducing SDS-PAGE.