NINJ2 - ninjurin 2 Gene

Homo sapiens

Gene ID: 4815 | Gene type: protein coding

About NINJ2

Cytogenetic location: 12p13.33 Genomic coordinates (GRCh38): 12:564,296-663,445 (from NCBI)

This gene has 6 transcripts (splice variants), 191 orthologues and 1 paralogue. Broad expression in lung (RPKM 12.3), bone marrow (RPKM 6.0) and 21 other tissues.

Summary

The protein encoded by this gene belongs to the ninjurin (for nerve injury induced) family. It is a cell surface adhesion protein that is upregulated in Schwann cells surrounding the distal segment of injured nerve, and promotes neurite outgrowth, thus may have a role in nerve regeneration after nerve injury. [provided by RefSeq, Oct 2011]

NINJ2 Products(4)

mRNA	Protein	Name
NM_001294345.2	NP_001281274.1	ninjurin-2 isoform 2
NM_001294346.2	NP_001281275.1	ninjurin-2 isoform 3
NM_001367996.1	NP_001354925.1	ninjurin-2 isoform 3
NM_016533.6	NP_057617.3	ninjurin-2 isoform 1

NINJ2 Protein Structure

Ninjurin

0
100
188 a.a.

Protein Preferred Names

Protein Names

ninjurin-2

nerve injury-induced protein 2

Recombinant NINJ2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P79415	Ninjurin-2 Protein, Human (His)	Q9NZG7 (M1-T65)	≥95%

Related Diseases

Diseases

Alias

Inflammatory Bowel Disease 4

IBD4

Idiopathic Peripheral Autonomic Neuropathy

Acrocallosal Syndrome

ACLS	Schinzel Acrocallosal Syndrome
Joubert Syndrome 12	Schinzel Syndrome 1
Acrocallosal Syndrome, Schinzel Type	Hallux Duplication, Postaxial Polydactyly, And Absence Of Corpus Callosum
Acs	Absence Of Corpus Callosum With Unusual Facial Appearance, Mental Deficiency, Duplication Of The Halluces And Polydactyly
Hallux Duplication Postaxial Polydactyly And Absence Of Corpus Callosum	JBTS12
Acrocallosal Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09299	NINJ2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	NINJ2	VGNC	VGNC:32079
Canis familiaris	NINJ2	VGNC	VGNC:43812
Felis catus	NINJ2	VGNC	VGNC:68496
Mus musculus	NINJ2	MGD	MGI:1352751
Rattus norvegicus	NINJ2	RGD	RGD:620552

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