TMEM86B - transmembrane protein 86B Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 255043
Summary
Enables D-lysine 5,6-aminomutase activity; alkenylglycerophosphocholine hydrolase activity; and identical protein binding activity. Involved in ether lipid metabolic process. Located in cytoplasm and membrane. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in gall bladder (RPKM 7.8), duodenum (RPKM 5.4) and 24 other tissues.
TMEM86B Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001372013.1 | NP_001358942.1 | lysoplasmalogenase TMEM86B isoform 2 |
| NM_173804.5 | NP_776165.3 | lysoplasmalogenase TMEM86B isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables D-lysine 5,6-aminomutase activity |
IDA
IDA: Inferred from direct assay
|
21515882 | GOA |
| enables alkenylglycerophosphocholine hydrolase activity |
IDA
IDA: Inferred from direct assay
|
21515882 | GOA |
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in ether lipid metabolic process |
IDA
IDA: Inferred from direct assay
|
21515882 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
21515882 | GOA |
| located in membrane |
IDA
IDA: Inferred from direct assay
|
21515882 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
TMEM86B Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
TMEM86B | Q8N661 | ZDHHC22 | Homo sapiens | Q8N966 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM248 | Homo sapiens | Q9NWD8 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM248 | Homo sapiens | Q9NWD8 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM248 | Homo sapiens | Q9NWD8 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | NINJ2 | Homo sapiens | Q9NZG7 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | NINJ2 | Homo sapiens | Q9NZG7 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MARCHF2 | Homo sapiens | Q9P0N8 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | PGRMC2 | Homo sapiens | O15173 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | PGRMC2 | Homo sapiens | O15173 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | RPRM | Homo sapiens | Q9NS64 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | VAPA | Homo sapiens | Q9P0L0 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | NEMP1 | Homo sapiens | O14524-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | NEMP1 | Homo sapiens | O14524-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM237 | Homo sapiens | Q96Q45-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GJA1 | Homo sapiens | P17302 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GJA1 | Homo sapiens | P17302 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | HIBADH | Homo sapiens | P31937 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | HIBADH | Homo sapiens | P31937 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MFF | Homo sapiens | Q9GZY8-5 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | FAXDC2 | Homo sapiens | Q96IV6 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM203 | Homo sapiens | Q969S6 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ASGR2 | Homo sapiens | P07307-3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ASGR2 | Homo sapiens | P07307-3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MS4A14 | Homo sapiens | Q96JA4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MS4A14 | Homo sapiens | Q96JA4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MS4A14 | Homo sapiens | Q96JA4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TREX1 | Homo sapiens | Q9NSU2-1 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MUC1 | Homo sapiens | P15941-11 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MUC1 | Homo sapiens | P15941-11 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SFXN5 | Homo sapiens | Q8TD22 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CLRN1 | Homo sapiens | P58418 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CLRN1 | Homo sapiens | P58418 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SSMEM1 | Homo sapiens | Q8WWF3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | PEX11G | Homo sapiens | Q96HA9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | EVI2B | Homo sapiens | P34910-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | EVI2B | Homo sapiens | P34910-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CCDC34 | Homo sapiens | Q96HJ3-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CCDC34 | Homo sapiens | Q96HJ3-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CCDC34 | Homo sapiens | Q96HJ3-2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | HSD17B13 | Homo sapiens | Q7Z5P4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | HSD17B13 | Homo sapiens | Q7Z5P4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM52B | Homo sapiens | Q4KMG9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM52B | Homo sapiens | Q4KMG9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TEX29 | Homo sapiens | Q8N6K0 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TEX29 | Homo sapiens | Q8N6K0 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TEX29 | Homo sapiens | Q8N6K0 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM14C | Homo sapiens | Q9P0S9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM14C | Homo sapiens | Q9P0S9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | BCL2L13 | Homo sapiens | Q9BXK5 | 25416956 | |
|
Intra
|
TMEM86B | Q8N661 | BCL2L13 | Homo sapiens | Q9BXK5 | 25416956 | |
|
Intra
|
TMEM86B | Q8N661 | BCL2L13 | Homo sapiens | Q9BXK5 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | BCL2L13 | Homo sapiens | Q9BXK5 | 25416956 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM14A | Homo sapiens | Q9Y6G1 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ARL6IP6 | Homo sapiens | Q8N6S5 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SLC39A9 | Homo sapiens | Q9NUM3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SLC39A9 | Homo sapiens | Q9NUM3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SLC39A9 | Homo sapiens | Q9NUM3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | LIME1 | Homo sapiens | Q9H400 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | LIME1 | Homo sapiens | Q9H400 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | LIME1 | Homo sapiens | Q9H400 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM60 | Homo sapiens | Q9H2L4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SFT2D1 | Homo sapiens | Q8WV19 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | q96fb2_human | Homo sapiens | Q96FB2 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GPR37L1 | Homo sapiens | O60883 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | LAPTM4B | Homo sapiens | Q86VI4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | LAPTM4B | Homo sapiens | Q86VI4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM106A | Homo sapiens | Q96A25 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM106A | Homo sapiens | Q96A25 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM106A | Homo sapiens | Q96A25 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | FKBP7 | Homo sapiens | Q9Y680 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | FKBP7 | Homo sapiens | Q9Y680 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | FKBP7 | Homo sapiens | Q9Y680 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MMGT1 | Homo sapiens | Q8N4V1 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MMGT1 | Homo sapiens | Q8N4V1 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CD53 | Homo sapiens | P19397 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CD53 | Homo sapiens | P19397 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | OTULINL | Homo sapiens | Q9NUU6 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GJA4 | Homo sapiens | P35212 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GJA4 | Homo sapiens | P35212 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | BIK | Homo sapiens | Q13323 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | BIK | Homo sapiens | Q13323 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GOLM1 | Homo sapiens | Q8NBJ4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GOLM1 | Homo sapiens | Q8NBJ4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | GOLM1 | Homo sapiens | Q8NBJ4 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | FXYD6 | Homo sapiens | Q9H0Q3 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MGST3 | Homo sapiens | O14880 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MGST3 | Homo sapiens | O14880 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | IER3IP1 | Homo sapiens | Q9Y5U9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | THAP4 | Homo sapiens | Q8WY91 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | THAP4 | Homo sapiens | Q8WY91 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | THAP4 | Homo sapiens | Q8WY91 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | STX8 | Homo sapiens | Q9UNK0 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | SLC35G2 | Homo sapiens | Q8TBE7 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | TMEM120A | Homo sapiens | Q9BXJ8 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | NDUFAF1 | Homo sapiens | Q9Y375 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | NDUFAF1 | Homo sapiens | Q9Y375 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | NDUFAF1 | Homo sapiens | Q9Y375 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | F11R | Homo sapiens | Q9Y624 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | F11R | Homo sapiens | Q9Y624 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | F11R | Homo sapiens | Q9Y624 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | USE1 | Homo sapiens | Q9NZ43 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | KIR2DL3 | Homo sapiens | P43628 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | KIR2DL3 | Homo sapiens | P43628 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | DNAJC30 | Homo sapiens | Q96LL9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | CCDC167 | Homo sapiens | Q9P0B6 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ERP29 | Homo sapiens | P30040 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | ERP29 | Homo sapiens | P30040 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MSMO1 | Homo sapiens | Q15800 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | MSMO1 | Homo sapiens | Q15800 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | RHBDD1 | Homo sapiens | Q8TEB9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | RHBDD1 | Homo sapiens | Q8TEB9 | 32296183 | |
|
Intra
|
TMEM86B | Q8N661 | RHBDD1 | Homo sapiens | Q8TEB9 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS14743 | TMEM86A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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