OTULINL - OTU deubiquitinase with linear linkage specificity like Gene

Also Known as NET20; FAM105A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54491

Summary

Located in cytoplasmic side of endoplasmic reticulum membrane and nuclear envelope. [provided by Alliance of Genome Resources, Jul 2025]
Broad expression in bone marrow (RPKM 12.7), colon (RPKM 9.2) and 21 other tissues.

OTULINL Products (1)

mRNA Protein Name
NM_019018.3 NP_061891.1 inactive ubiquitin thioesterase OTULINL

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
NOT enables ubiquitin binding IDA
IDA: Inferred from direct assay
31056421 GOA
NOT enables ubiquitin-like protein peptidase activity IDA
IDA: Inferred from direct assay
31056421 GOA
Biological Process GO Annotation Evidence References Source
NOT involved in protein deubiquitination IDA
IDA: Inferred from direct assay
31056421 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
31056421 GOA
located in cytoplasmic side of endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
31056421 GOA
colocalizes with nuclear envelope IDA
IDA: Inferred from direct assay
31056421 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

OTULINL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
OTULINL Q9NUU6 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
Intra
OTULINL Q9NUU6 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 SLC30A8 Homo sapiens Q8IWU4
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 SLC30A8 Homo sapiens Q8IWU4
Y2H Array
32296183
Intra
OTULINL Q9NUU6 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
Intra
OTULINL Q9NUU6 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
Intra
OTULINL Q9NUU6 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
OTULINL Q9NUU6 GOLT1A Homo sapiens Q6ZVE7
Y2H Array
32296183
Intra
OTULINL Q9NUU6 GOLT1A Homo sapiens Q6ZVE7
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 TMEM86B Homo sapiens Q8N661
Y2H Array
32296183
Intra
OTULINL Q9NUU6 TMEM86B Homo sapiens Q8N661
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 HTRA2 Homo sapiens O43464
Y2H Array
32814053
Intra
OTULINL Q9NUU6 HTRA2 Homo sapiens O43464
Y2H Pooling
32814053
Intra
OTULINL Q9NUU6 HTRA2 Homo sapiens O43464
Validated Y2H
32814053
Intra
OTULINL Q9NUU6 TMX2 Homo sapiens Q9Y320
Y2H Array
32296183
Intra
OTULINL Q9NUU6 TMX2 Homo sapiens Q9Y320
Validated Y2H
32296183
Intra
OTULINL Q9NUU6 TMX2 Homo sapiens Q9Y320
Y2H Prey Pooling
32296183
Intra
OTULINL Q9NUU6 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
OTULINL Q9NUU6 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS19070 Otulin Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09878 OTULIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25560 Otulin Rat Pre-designed siRNA Set A Pre-designed Set / Unkown