CD299 Antibody (YA4491)(PBS only)

Cat. No.: HY-P84794A: Fiche technique User Guide for Antibodies
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CD299 Antibody (YA4491) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD299.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

CD299 Antibody (YA4491) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD299.

Host

Mouse

Masse moléculaire

Predicted band size: 32 kDa;

Observed band size: 37 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q9H2X3

Gene ID

10332 [NCBI]

Immunogen

Purified recombinant fragment of human CD299 (AA: extra 237-399) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Pureté	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates; (Microbial infection) Acts as an attachment receptor for Ebolavirus; (Microbial infection) Acts as an attachment receptor for Hepatitis C virus; (Microbial infection) Acts as an attachment receptor for HIV-1; (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E; (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5; (Microbial infection) Acts as an attachment receptor for Influenzavirus; (Microbial infection) Acts as an attachment receptor for SARS-CoV; (Microbial infection) Acts as an attachment receptor for West-nile virus; (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus; (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein; (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule

Subcellular Localization：Cell membrane; Single-pass type II membrane protein; Cell membrane; Single-pass type II membrane protein; Cell membrane; Single-pass type II membrane protein; Secreted; Secreted; Secreted; Secreted

Expression：
Tissue_specificity:Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells

Isoforms & Post-Translational Modification：Q9H2X3 has 10 isomers: Q9H2X3-1: 45350 Da (predicted); Q9H2X3-2: 30481 Da (predicted); Q9H2X3-3: 36769 Da (predicted); Q9H2X3-4: 26283 Da (predicted); Q9H2X3-5: 37954 Da (predicted); Q9H2X3-6: 28373 Da (predicted); Q9H2X3-7: 30131 Da (predicted); Q9H2X3-8: 42724 Da (predicted); Q9H2X3-9: 33528 Da (predicted); Q9H2X3-10: 24408 Da (predicted).

Subunit：Homotetramer

Synonyms

CLEC4M; LSIGN; CD209L; L-SIGN; DCSIGNR; HP10347; DC-SIGN2; DC-SIGNR

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/mkn-7-cell.html