CD299 Antibody (YA4491)
(Synonyms: CLEC4M; LSIGN; CD209L; L-SIGN; DCSIGNR; HP10347; DC-SIGN2; DC-SIGNR)CD299 Antibody (YA4491) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD299.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:400 | 1:10000 |
Product Details
CD299 Antibody (YA4491) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD299.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 37 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 32 kDa
Purified recombinant fragment of human CD299 (AA: extra 237-399) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD299 is a Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates; (Microbial infection) Acts as an attachment receptor for Ebolavirus; (Microbial infection) Acts as an attachment receptor for Hepatitis C virus; (Microbial infection) Acts as an attachment receptor for HIV-1; (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E; (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5; (Microbial infection) Acts as an attachment receptor for Influenzavirus; (Microbial infection) Acts as an attachment receptor for SARS-CoV; (Microbial infection) Acts as an attachment receptor for West-nile virus; (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus; (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein; (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule
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Subcellular Localization
Cell membrane; Single-pass type II membrane protein; Cell membrane; Single-pass type II membrane protein; Cell membrane; Single-pass type II membrane protein; Secreted; Secreted; Secreted; Secreted
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Expression
Tissue_specificity:Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells -
Isoforms & Post-Translational Modification
Q9H2X3 has 10 isomers: Q9H2X3-1: 45350 Da (predicted); Q9H2X3-2: 30481 Da (predicted); Q9H2X3-3: 36769 Da (predicted); Q9H2X3-4: 26283 Da (predicted); Q9H2X3-5: 37954 Da (predicted); Q9H2X3-6: 28373 Da (predicted); Q9H2X3-7: 30131 Da (predicted); Q9H2X3-8: 42724 Da (predicted); Q9H2X3-9: 33528 Da (predicted); Q9H2X3-10: 24408 Da (predicted).
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Subunit
Homotetramer
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SwissProt ID
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Synonyms
CLEC4M; LSIGN; CD209L; L-SIGN; DCSIGNR; HP10347; DC-SIGN2; DC-SIGNR
Documentation
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