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  5. CD299 Antibody (YA4491)

CD299 Antibody (YA4491)

Cat. No.: HY-P84794
User Guide for Antibodies Technical Support

CD299 Antibody (YA4491) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD299.

For research use only. We do not sell to patients.

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20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

CD299 Antibody (YA4491) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD299.
Host

Mouse
Clonality

Monoclonal
Molecular Weight
Predicted band size: 32 kDa;
Observed band size: 37 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Purified recombinant fragment of human CD299 (AA: extra 237-399) expressed in E. Coli.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:2000
FC
FC: Flow Cytometry
1:200-1:400
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
Purity affinity purified. Conjugation Non-conjugated
Modification Unmodified Isotype IgG1
Appearance

Liquid
Formulation

Supplied in PBS with 0.05% sodium azide
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates; (Microbial infection) Acts as an attachment receptor for Ebolavirus; (Microbial infection) Acts as an attachment receptor for Hepatitis C virus; (Microbial infection) Acts as an attachment receptor for HIV-1; (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E; (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5; (Microbial infection) Acts as an attachment receptor for Influenzavirus; (Microbial infection) Acts as an attachment receptor for SARS-CoV; (Microbial infection) Acts as an attachment receptor for West-nile virus; (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus; (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein; (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule
Subcellular Localization：Cell membrane; Single-pass type II membrane protein; Cell membrane; Single-pass type II membrane protein; Cell membrane; Single-pass type II membrane protein; Secreted; Secreted; Secreted; Secreted
Expression：
Tissue_specificity:Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells
Isoforms & Post-Translational Modification：Q9H2X3 has 10 isomers: Q9H2X3-1: 45350 Da (predicted); Q9H2X3-2: 30481 Da (predicted); Q9H2X3-3: 36769 Da (predicted); Q9H2X3-4: 26283 Da (predicted); Q9H2X3-5: 37954 Da (predicted); Q9H2X3-6: 28373 Da (predicted); Q9H2X3-7: 30131 Da (predicted); Q9H2X3-8: 42724 Da (predicted); Q9H2X3-9: 33528 Da (predicted); Q9H2X3-10: 24408 Da (predicted).
Subunit：Homotetramer
Synonyms
CLEC4M; LSIGN; CD209L; L-SIGN; DCSIGNR; HP10347; DC-SIGN2; DC-SIGNR
Documentation
User Guide for Antibodies (1077 KB)

CD299 Antibody (YA4491) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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