FAXDC2 - fatty acid hydroxylase domain containing 2 Gene
Also Known as C5orf4
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 10826
Summary
Predicted to enable C-4 methylsterol oxidase activity. Involved in positive regulation of megakaryocyte differentiation and positive regulation of protein phosphorylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in liver (RPKM 20.9), ovary (RPKM 19.8) and 25 other tissues.
FAXDC2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_032385.5 | NP_115761.2 | fatty acid hydroxylase domain-containing protein 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in positive regulation of megakaryocyte differentiation |
IMP
IMP: Inferred from mutant phenotype
|
27689744 | GOA |
| involved in positive regulation of protein phosphorylation |
IMP
IMP: Inferred from mutant phenotype
|
27689744 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
27689744 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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FAXDC2 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
FAXDC2 | Q96IV6 | RETREG3 | Homo sapiens | Q86VR2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | RETREG3 | Homo sapiens | Q86VR2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | SLC30A8 | Homo sapiens | Q8IWU4 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | SLC30A8 | Homo sapiens | Q8IWU4 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CYB5R3 | Homo sapiens | P00387 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CYB5R3 | Homo sapiens | P00387 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | PGRMC2 | Homo sapiens | O15173 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | PGRMC2 | Homo sapiens | O15173 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | NEMP1 | Homo sapiens | O14524-2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | NEMP1 | Homo sapiens | O14524-2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | GOLT1A | Homo sapiens | Q6ZVE7 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | GOLT1A | Homo sapiens | Q6ZVE7 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | HSD17B13 | Homo sapiens | Q7Z5P4 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | HSD17B13 | Homo sapiens | Q7Z5P4 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ELOVL4 | Homo sapiens | Q9GZR5 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CGRRF1 | Homo sapiens | Q99675 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CGRRF1 | Homo sapiens | Q99675 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CGRRF1 | Homo sapiens | Q99675 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMEM86B | Homo sapiens | Q8N661 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMEM86B | Homo sapiens | Q8N661 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMEM106C | Homo sapiens | Q9BVX2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMEM106C | Homo sapiens | Q9BVX2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMEM106C | Homo sapiens | Q9BVX2 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | FFAR2 | Homo sapiens | O15552 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | FFAR2 | Homo sapiens | O15552 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | SLC10A1 | Homo sapiens | Q14973 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | SLC10A1 | Homo sapiens | Q14973 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CREB3L1 | Homo sapiens | Q96BA8 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CREB3L1 | Homo sapiens | Q96BA8 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | PANX1 | Homo sapiens | Q96RD7 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | PANX1 | Homo sapiens | Q96RD7 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | PANX1 | Homo sapiens | Q96RD7 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMEM139 | Homo sapiens | Q8IV31 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | TMEM139 | Homo sapiens | Q8IV31 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | MGST3 | Homo sapiens | O14880 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | MGST3 | Homo sapiens | O14880 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CLDN7 | Homo sapiens | O95471 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CLDN7 | Homo sapiens | O95471 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | STX4 | Homo sapiens | Q12846 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | STX4 | Homo sapiens | Q12846 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
FAXDC2 | Q96IV6 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction