TMEM106C - transmembrane protein 106C Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79022

About TMEM106C

This gene has 22 transcripts (splice variants) and 171 orthologues. Ubiquitous expression in colon (RPKM 50.8), small intestine (RPKM 47.7) and 25 other tissues.

Summary

Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM106C Products (4)

mRNA Protein Name
NM_001143841.2 NP_001137313.1 transmembrane protein 106C isoform b
NM_001143842.2 NP_001137314.1 transmembrane protein 106C isoform a
NM_001143843.2 NP_001137315.1 transmembrane protein 106C isoform b
NM_024056.4 NP_076961.1 transmembrane protein 106C isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM106C Protein Structure

DUF1356

DUF1356: Protein of unknown function (DUF1356) (21 - 248)

  • 0
  • 100
  • 200
  • 250 a.a.
Protein Preferred Names Protein Names

transmembrane protein 106C

  • endoplasmic reticulum membrane protein overexpressed in cancer

TMEM106C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM106C Q9BVX2 MARCHF2 Homo sapiens Q9P0N8
Validated Y2H
32296183
Intra
TMEM106C Q9BVX2 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra
TMEM106C Q9BVX2 AIG1 Homo sapiens Q9NVV5-2
Validated Y2H
32296183
Intra
TMEM106C Q9BVX2 YIPF6 Homo sapiens Q96EC8
Y2H Array
32296183
Intra
TMEM106C Q9BVX2 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra
TMEM106C Q9BVX2 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
TMEM106C Q9BVX2 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Intra
TMEM106C Q9BVX2 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14647 TMEM106C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TMEM106C VGNC VGNC:47447
Mus musculus TMEM106C MGD MGI:1196384
Rattus norvegicus TMEM106C RGD RGD:1311532
Bos taurus TMEM106C VGNC VGNC:35946
Felis catus TMEM106C VGNC VGNC:66257
Macaca mulatta TMEM106C VGNC VGNC:79741
Others TMEM106C NCBI