MGST3 - microsomal glutathione S-transferase 3 Gene

Homo sapiens

Also known as GST-III

Gene ID: 4259 | Gene type: protein coding

About MGST3

Cytogenetic location: 1q24.1 Genomic coordinates (GRCh38): 1:165,631,234-165,656,136 (from NCBI)

This gene has 14 transcripts (splice variants), 210 orthologues and 3 paralogues. Ubiquitous expression in heart (RPKM 114.7), fat (RPKM 75.6) and 24 other tissues.

Summary

This gene encodes a member of the MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an Enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This Enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.[provided by RefSeq, May 2011]

MGST3 Products(1)

mRNA	Protein	Name
NM_004528.4	NP_004519.1	microsomal glutathione S-transferase 3

MGST3 Protein Structure

MAPEG

0
100
152 a.a.

Protein Preferred Names

Protein Names

microsomal glutathione S-transferase 3

LTC4 synthase MGST3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08418	MGST3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MGST3	VGNC	VGNC:68253
Bos taurus	MGST3	VGNC	VGNC:31453
Mus musculus	MGST3	MGD	MGI:1913697
Macaca mulatta	MGST3	VGNC	VGNC:74720
Canis familiaris	MGST3	VGNC	VGNC:53121
Rattus norvegicus	MGST3	RGD	RGD:1306373

Name
Email *

	Sorry, but the email address you supplied was invalid.