AGPAT4 - 1-acylglycerol-3-phosphate O-acyltransferase 4 Gene

Homo sapiens

Also known as LPAAT4; LPLAT4; 1-AGPAT4; dJ473J16.2; LPAAT-delta

Gene ID: 56895 | Gene type: protein coding

About AGPAT4

Cytogenetic location: 6q26 Genomic coordinates (GRCh38): 6:161,129,967-161,274,061 (from NCBI)

This gene has 6 transcripts (splice variants), 209 orthologues and 4 paralogues. Broad expression in brain (RPKM 9.7), placenta (RPKM 3.7) and 18 other tissues.

Summary

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008]

AGPAT4 Products(1)

mRNA	Protein	Name
NM_020133.3	NP_064518.1	1-acyl-sn-glycerol-3-phosphate acyltransferase delta

AGPAT4 Protein Structure

Acyltransferase

0
100
200
300
378 a.a.

Protein Preferred Names

Protein Names

1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1-AGP acyltransferase 4

Related Diseases

Diseases

Alias

Fetal Akinesia Deformation Sequence 4

FADS4	Fetal Akinesia Deformation Sequence Syndrome 4
Akinesia, Fetal, Deformation Sequence, Type 4

Complete Generalized Lipodystrophy

Congenital Generalized Lipodystrophy

Berardinelli-Seip Congenital Lipodystrophy	Berardinelli-Seip Syndrome
Brunzell Syndrome	Bscl
Generalized Lipodystrophy	Lipodystrophy, Congenital Generalized
Seip Syndrome	Total Lipodystrophy
Cgl	Lipoatrophic Diabetes
Lipodystrophy, Generalized, Congenital	Familial Generalized Lipodystrophy
Congenital Generalized Lipodystrophy Type 2	Lipoatrophic Diabetes Mellitus
Familial Partial Lipodystrophy, Type 2

Fetal Akinesia Deformation Sequence 1

Fetal Akinesia Deformation Sequence	Fads
Fetal Akinesia Sequence	FADS1
Arthrogryposis Multiplex Congenita With Pulmonary Hypoplasia	Pena-Shokeir Syndrome Type 1
Fetal Akinesia Deformation Sequence Syndrome	Arthrogryposis Multiplex Congenita-Pulmonary Hypoplasia Syndrome
Arthrogryposis Multiplex Congenita Pulmonary Hypoplasia	Pena-Shokeir Syndrome, Type I
Foetal Akinesia Deformation Sequence Syndrome	Foetal Akinesia Sequence
Fetal Akinesia Deformation Sequence Syndrome 1	Pena-Shokeir Syndrome, Type 1
Pena Shokeir Syndrome, Type 1	Akinesia, Fetal, Deformation Sequence
Akinesia, Fetal, Deformation Sequence, Type 1	Pena-Shokeir Syndrome Type I

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00459	AGPAT4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	AGPAT4	VGNC	VGNC:59687
Canis familiaris	AGPAT4	VGNC	VGNC:37713
Bos taurus	AGPAT4	VGNC	VGNC:25737
Macaca mulatta	AGPAT4	VGNC	VGNC:69654
Mus musculus	AGPAT4	MGD	MGI:1915512
Rattus norvegicus	AGPAT4	RGD	RGD:619916
Others	AGPAT4	NCBI

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