TMEM14B - transmembrane protein 14B Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 81853
Summary
Enables identical protein binding activity. Involved in cerebral cortex development; neural precursor cell proliferation; and regulation of G1/S transition of mitotic cell cycle. Predicted to be located in membrane. Predicted to be active in mitochondrial membrane. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 31.1), bone marrow (RPKM 27.9) and 25 other tissues.
TMEM14B Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001127711.3 | NP_001121183.1 | transmembrane protein 14B isoform b |
| NM_001286484.2 | NP_001273413.1 | transmembrane protein 14B isoform c |
| NM_001286488.2 | NP_001273417.1 | transmembrane protein 14B isoform d |
| NM_001286489.2 | NP_001273418.1 | transmembrane protein 14B isoform e |
| NM_030969.5 | NP_112231.3 | transmembrane protein 14B isoform a |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
29033352 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cerebral cortex development |
IMP
IMP: Inferred from mutant phenotype
|
29033352 | GOA |
| involved in neural precursor cell proliferation |
IDA
IDA: Inferred from direct assay
|
29033352 | GOA |
| involved in regulation of G1/S transition of mitotic cell cycle |
IDA
IDA: Inferred from direct assay
|
29033352 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
TMEM14B Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
TMEM14B | Q9NUH8 | SLC30A8 | Homo sapiens | Q8IWU4 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC30A8 | Homo sapiens | Q8IWU4 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | JAGN1 | Homo sapiens | Q8N5M9 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | JAGN1 | Homo sapiens | Q8N5M9 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | NINJ2 | Homo sapiens | Q9NZG7 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | B4GALT7 | Homo sapiens | Q9UBV7 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SERP1 | Homo sapiens | Q9Y6X1 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CNIH4 | Homo sapiens | Q9P003 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CNIH4 | Homo sapiens | Q9P003 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CNIH4 | Homo sapiens | Q9P003 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | HSD17B11 | Homo sapiens | Q8NBQ5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | HSD17B11 | Homo sapiens | Q8NBQ5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | ORMDL1 | Homo sapiens | Q9P0S3 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | GDAP1 | Homo sapiens | Q8TB36 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | GDAP1 | Homo sapiens | Q8TB36 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TVP23B | Homo sapiens | Q9NYZ1 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | HIBADH | Homo sapiens | P31937 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | GPX8 | Homo sapiens | Q8TED1 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TIMM22 | Homo sapiens | Q9Y584 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | LPAR3 | Homo sapiens | Q9UBY5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | LRCH1 | Homo sapiens | Q9Y2L9-3 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | STOM | Homo sapiens | P27105 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC48A1 | Homo sapiens | Q6P1K1 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CEPT1 | Homo sapiens | Q9Y6K0 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC7A8 | Homo sapiens | Q9UHI5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC35G1 | Homo sapiens | Q2M3R5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC35G1 | Homo sapiens | Q2M3R5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | GPR152 | Homo sapiens | Q8TDT2 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | C10orf67 | Homo sapiens | Q8IYJ2-2 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | C10orf67 | Homo sapiens | Q8IYJ2-2 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SCN3B | Homo sapiens | Q9NY72 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SCN3B | Homo sapiens | Q9NY72 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SCN3B | Homo sapiens | Q9NY72 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC18A1 | Homo sapiens | P54219-3 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC18A1 | Homo sapiens | P54219-3 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC16A10 | Homo sapiens | Q8TF71 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC16A10 | Homo sapiens | Q8TF71 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TMEM69 | Homo sapiens | Q5SWH9 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC2A6 | Homo sapiens | Q9UGQ3 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC2A6 | Homo sapiens | Q9UGQ3 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SLC2A6 | Homo sapiens | Q9UGQ3 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CPLX4 | Homo sapiens | Q7Z7G2 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CPLX4 | Homo sapiens | Q7Z7G2 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | APOC4 | Homo sapiens | P55056 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | APOC4 | Homo sapiens | P55056 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | FAM209A | Homo sapiens | Q5JX71 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TMEM14C | Homo sapiens | Q9P0S9 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | MARCHF5 | Homo sapiens | Q9NX47 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | PAGE1 | Homo sapiens | O75459 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | PAGE1 | Homo sapiens | O75459 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TMEM14A | Homo sapiens | Q9Y6G1 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | UBIAD1 | Homo sapiens | Q9Y5Z9 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | NAT8 | Homo sapiens | Q9UHE5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | ACSL5 | Homo sapiens | Q9ULC5 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | FIS1 | Homo sapiens | Q9Y3D6 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | PLLP | Homo sapiens | Q9Y342 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | SAR1B | Homo sapiens | Q9Y6B6 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | OTULINL | Homo sapiens | Q9NUU6 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CREB3L1 | Homo sapiens | Q96BA8 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CREB3L1 | Homo sapiens | Q96BA8 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CIDEB | Homo sapiens | Q9UHD4 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CIDEB | Homo sapiens | Q9UHD4 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CIDEB | Homo sapiens | Q9UHD4 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | RABAC1 | Homo sapiens | Q9UI14 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | ARL8B | Homo sapiens | Q9NVJ2 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | ZFPL1 | Homo sapiens | O95159 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | VTI1B | Homo sapiens | Q9UEU0 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | IER3IP1 | Homo sapiens | Q9Y5U9 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | TMEM51 | Homo sapiens | Q9NW97 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | STX8 | Homo sapiens | Q9UNK0 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | LEPROTL1 | Homo sapiens | O95214 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | LEPROTL1 | Homo sapiens | O95214 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | YIPF1 | Homo sapiens | Q9Y548 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | KCNA1 | Homo sapiens | Q09470 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | KCNA1 | Homo sapiens | Q09470 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | INSIG2 | Homo sapiens | Q9Y5U4 | 32296183 | |
|
Intra
|
TMEM14B | Q9NUH8 | UBE2J1 | Homo sapiens | Q9Y385 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(8)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS14668 | TMEM140 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14669 | TMEM145 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14670 | TMEM147 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14671 | TMEM14C Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14690 | TMEM184B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS14723 | TMEM41B Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS20657 | Tmem41b Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS27168 | Tmem41b Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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