RABAC1 - Rab acceptor 1 Gene

Also Known as PRA1; YIP3; PRAF1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 10567

About RABAC1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,956,683-41,959,321 (from NCBI)

This gene has 10 transcripts (splice variants) and 186 orthologues. Ubiquitous expression in fat (RPKM 42.3), stomach (RPKM 42.2) and 25 other tissues.

Summary

Enables identical protein binding activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

RABAC1 Products (1)

mRNA	Protein	Name
NM_006423.3	NP_006414.2	prenylated Rab acceptor protein 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	16169070	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RABAC1 Protein Structure

PRA1

0
100
185 a.a.

Protein Preferred Names	Protein Names
prenylated Rab acceptor protein 1	PRA1 domain family 1

RABAC1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	RABAC1	Q9UI14	UBE2I	Homo sapiens	Q7KZS0	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	UBE2I	Homo sapiens	Q7KZS0	Y2H Array	32296183
Intra	RABAC1	Q9UI14	RETREG3	Homo sapiens	Q86VR2	Y2H Array	32296183
Intra	RABAC1	Q9UI14	RETREG3	Homo sapiens	Q86VR2	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	SYT16	Homo sapiens	Q17RD7	Y2H Array	31515488
Intra	RABAC1	Q9UI14	SYT16	Homo sapiens	Q17RD7	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	SYT16	Homo sapiens	Q17RD7	Y2H Array	25416956
Intra	RABAC1	Q9UI14	SYT16	Homo sapiens	Q17RD7	Y2H Array	29892012
Intra	RABAC1	Q9UI14	SNX10	Homo sapiens	Q8N5Z3	Y2H Array	25416956
Intra	RABAC1	Q9UI14	SNX10	Homo sapiens	Q8N5Z3	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	NDRG4	Homo sapiens	Q9ULP0	Validated Y2H	25416956
Intra	RABAC1	Q9UI14	NDRG4	Homo sapiens	Q9ULP0	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	SNX11	Homo sapiens	Q9Y5W9	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	SNX11	Homo sapiens	Q9Y5W9	Y2H Array	32296183
Intra	RABAC1	Q9UI14	SNX10	Homo sapiens	Q9Y5X0	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	SSR3	Homo sapiens	Q9UNL2	Y2H Array	32296183
Intra	RABAC1	Q9UI14	SSR3	Homo sapiens	Q9UNL2	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	SSR3	Homo sapiens	Q9UNL2	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	STOML2	Homo sapiens	Q9UJZ1	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	STOML2	Homo sapiens	Q9UJZ1	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	STOML2	Homo sapiens	Q9UJZ1	Y2H Array	32296183
Intra	RABAC1	Q9UI14	REEP2	Homo sapiens	Q9BRK0	Y2H Array	32296183
Intra	RABAC1	Q9UI14	REEP2	Homo sapiens	Q9BRK0	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	NDRG4	Homo sapiens	Q9ULP0-2	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	TMEM42	Homo sapiens	Q69YG0	Y2H Array	32296183
Intra	RABAC1	Q9UI14	TMEM42	Homo sapiens	Q69YG0	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	WIPI2	Homo sapiens	Q9Y4P8-4	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	RABAC1	Q9UI14	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	SLAMF6	Homo sapiens	Q96DU3	Y2H Array	32296183
Intra	RABAC1	Q9UI14	SLAMF6	Homo sapiens	Q96DU3	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	REEP5	Homo sapiens	Q00765	Y2H	21900206
Intra	RABAC1	Q9UI14	CRB3	Homo sapiens	Q9BUF7-2	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	CRB3	Homo sapiens	Q9BUF7-2	Y2H Array	32296183
Intra	RABAC1	Q9UI14	SNX8	Homo sapiens	Q9Y5X2	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Array	32296183
Intra	RABAC1	Q9UI14	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	EI24	Homo sapiens	O14681	Y2H Array	32296183
Intra	RABAC1	Q9UI14	EI24	Homo sapiens	O14681	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	LEMD3	Homo sapiens	Q9Y2U8	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	LEMD3	Homo sapiens	Q9Y2U8	Y2H Array	32296183
Intra	RABAC1	Q9UI14	LEMD3	Homo sapiens	Q9Y2U8	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	SH3GLB1	Homo sapiens	Q9Y371	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	SNX1	Homo sapiens	Q13596	Y2H Array	25416956
Intra	RABAC1	Q9UI14	ZFYVE21	Homo sapiens	Q9BQ24	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	ZFYVE21	Homo sapiens	Q9BQ24	Validated Y2H	25416956
Intra	RABAC1	Q9UI14	RNF5	Homo sapiens	Q99942	Y2H Array	32296183
Intra	RABAC1	Q9UI14	RNF5	Homo sapiens	Q99942	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	LTBR	Homo sapiens	P36941	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	LTBR	Homo sapiens	P36941	Y2H Array	32296183
Intra	RABAC1	Q9UI14	EMP1	Homo sapiens	P54849	Y2H Array	32296183
Intra	RABAC1	Q9UI14	EMP1	Homo sapiens	P54849	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	STIM1	Homo sapiens	Q13586	Y2H Array	32296183
Intra	RABAC1	Q9UI14	STIM1	Homo sapiens	Q13586	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
Intra	RABAC1	Q9UI14	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	SH3GL3	Homo sapiens	Q8IVP1	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	SH3GL3	Homo sapiens	Q8IVP1	Y2H Array	32296183
Intra	RABAC1	Q9UI14	COQ8A	Homo sapiens	Q8NI60	Y2H Array	25416956
Intra	RABAC1	Q9UI14	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	25416956
Intra	RABAC1	Q9UI14	COQ8A	Homo sapiens	Q8NI60	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	RABAC1	Homo sapiens	Q9UI14	Y2H Array	19060904
Intra	RABAC1	Q9UI14	NTAQ1	Homo sapiens	Q96HA8	Y2H Array	32296183
Intra	RABAC1	Q9UI14	NTAQ1	Homo sapiens	Q96HA8	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	NTAQ1	Homo sapiens	Q96HA8	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	RABAC1	Homo sapiens	Q9UI14	Y2H Pooling	19060904
Intra	RABAC1	Q9UI14	RABAC1	Homo sapiens	Q9UI14	Y2H Pooling	16169070
Intra	RABAC1	Q9UI14	RABAC1	Homo sapiens	Q9UI14	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	COQ8A	Homo sapiens	Q8NI60	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	ABHD4	Homo sapiens	Q8TB40	Y2H Array	32296183
Intra	RABAC1	Q9UI14	ABHD4	Homo sapiens	Q8TB40	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	FXR1	Homo sapiens	P51114	Anti Tag CoIP	21653829
Intra	RABAC1	Q9UI14	FXR1	Homo sapiens	P51114	Y2H Pooling	21653829
Intra	RABAC1	Q9UI14	DUSP12	Homo sapiens	Q9UNI6	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	DUSP12	Homo sapiens	Q9UNI6	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	DUSP12	Homo sapiens	Q9UNI6	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	WIPI2	Homo sapiens	Q9Y4P8	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	WIPI2	Homo sapiens	Q9Y4P8	Validated Y2H	25416956
Intra	RABAC1	Q9UI14	WIPI2	Homo sapiens	Q9Y4P8	Y2H Array	25416956
Intra	RABAC1	Q9UI14	C6orf47	Homo sapiens	O95873	Y2H Array	32296183
Intra	RABAC1	Q9UI14	C6orf47	Homo sapiens	O95873	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	SNX15	Homo sapiens	Q9NRS6	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	SNX15	Homo sapiens	Q9NRS6	Validated Y2H	25416956
Intra	RABAC1	Q9UI14	FXR2	Homo sapiens	P51116	Y2H Pooling	19060904
Intra	RABAC1	Q9UI14	FXR2	Homo sapiens	P51116	Y2H Array	19060904
Intra	RABAC1	Q9UI14	NUDT18	Homo sapiens	Q6ZVK8	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	NIF3L1	Homo sapiens	Q9GZT8	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Array	19060904
Intra	RABAC1	Q9UI14	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Pooling	19060904
Intra	RABAC1	Q9UI14	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	F11R	Homo sapiens	Q9Y624	Validated Y2H	32296183
Intra	RABAC1	Q9UI14	F11R	Homo sapiens	Q9Y624	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	F11R	Homo sapiens	Q9Y624	Y2H Array	32296183
Intra	RABAC1	Q9UI14	SPG21	Homo sapiens	Q9NZD8	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	SPG21	Homo sapiens	Q9NZD8	Y2H Array	25416956
Intra	RABAC1	Q9UI14	TRIM32	Homo sapiens	Q13049	Validated Y2H	25416956
Intra	RABAC1	Q9UI14	TRIM32	Homo sapiens	Q13049	Y2H Array	25416956
Intra	RABAC1	Q9UI14	MIEF2	Homo sapiens	Q96C03	Y2H Pooling	19060904
Intra	RABAC1	Q9UI14	MIEF2	Homo sapiens	Q96C03	Y2H Pooling	16189514
Intra	RABAC1	Q9UI14	MIEF2	Homo sapiens	Q96C03	Y2H Array	19060904
Intra	RABAC1	Q9UI14	NDRG2	Homo sapiens	Q9UN36-1	Y2H	23068607
Intra	RABAC1	Q9UI14	NDRG2	Homo sapiens	Q9UN36-1	Pull Down	23068607
Intra	RABAC1	Q9UI14	NDRG2	Homo sapiens	Q9UN36-1	IF	23068607
Intra	RABAC1	Q9UI14	NDRG2	Homo sapiens	Q9UN36-1	Anti Tag CoIP	23068607
Intra	RABAC1	Q9UI14	TMEM115	Homo sapiens	Q12893	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	TMEM115	Homo sapiens	Q12893	Y2H Array	32296183
Intra	RABAC1	Q9UI14	CYBRD1	Homo sapiens	Q53TN4	Y2H Array	32296183
Intra	RABAC1	Q9UI14	CYBRD1	Homo sapiens	Q53TN4	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
Intra	RABAC1	Q9UI14	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183
Intra	RABAC1	Q9UI14	RIC8A	Homo sapiens	Q9NPQ8-4	Y2H Prey Pooling	25416956
Intra	RABAC1	Q9UI14	SNCA	Homo sapiens	P37840	Anti Bait CoIP	21798244
Intra	RABAC1	Q9UI14	SNCA	Homo sapiens	P37840	Phage Display	21798244
Cross	RABAC1	Q9UI14	LMP1	Epstein-Barr virus	P03230	Y2H	16917502
Cross	RABAC1	Q9UI14	LMP1	Epstein-Barr virus	P03230	FRET	16917502
Cross	RABAC1	Q9UI14	LMP1	Epstein-Barr virus	P03230	Imaging	16917502
Cross	RABAC1	Q9UI14	LMP1	Epstein-Barr virus	P03230	Anti Tag CoIP	16917502

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Pontocerebellar Hypoplasia, Type 3	Pontocerebellar Hypoplasia Type 3 Cerebellar Atrophy With Progressive Microcephaly PCH3 Clam Pch With Optic Atrophy Pontocerebellar Hypoplasia 3 Hypoplasia, Pontocerebellar, Type 3
Subvalvular Aortic Stenosis	Fixed Subaortic Stenosis Subaortic Stenosis Aortic Stenosis, Subvalvular
Cone-Rod Dystrophy 1	CORD1 Crd1 Cone-Rod Retinal Dystrophy-1 Retinitis Pigmentosa 1
Vulvovaginal Candidiasis	Candidiasis Of Vulva And Vagina Candidiasis, Vulvovaginal Candidal Vulvovaginitis Candidal: Cervix Monilial Vulvovaginitis Candidiasis Vulvovaginal
Neuropathy, Congenital Hypomyelinating, 1, Autosomal Recessive	Charcot-Marie-Tooth Disease Type 4 Charcot-Marie-Tooth Disease Type 4e Hereditary Motor And Sensory Neuropathy Cmt4e CHN1 Hypomyelinating Neuropathy, Congenital, 1 Charcot-Marie-Tooth Neuropathy Type 4e Neuropathy, Congenital Hypomyelinating, 1 Ar-Cmt1 Autosomal Recessive Demyelinating Charcot-Marie-Tooth Cmt4 Neuropathy, Congenital Hypomyelinating Or Amyelinating, Autosomal Recessive Hypomyelination, Severe Congenital Charcot-Marie-Tooth Disease, Type 4e Charcot-Marie-Tooth Neuropathy, Type 4e Autosomal Recessive Congenital Hypomyelinating Or Amyelinating Neuropathy Autosomal Recessive Congenital Hypomyelinating Neuropathy Congenital Amyelinating Neuropathy Congenital Hypomyelinating Neuropathy Autosomal Recessive Neuropathy, Congenital Hypomyelinating Or Amyelinating Severe Congenital Hypomyelination Hereditary Sensory Motor Neuropathy Charcot-Marie-Tooth Disease, Demyelinating, Autosomal Recessive Neuropathy, Hypomyelinating, Congenital, Type 1 Neuropathy, Motor And Sensory, Hereditary Congenital Hypomyelinating Neuropathy Hereditary Motor And Sensory Neuropathies Hereditary Sensorimotor Neuropathy Hmsn - [Hereditary Motor And Sensory Neuropathy] Hsmn - [Hereditary Sensory And Motor Neuropathy] Hereditary Motor And Sensory Neuropathy, Types I-Iv
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11581	RABAC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	RABAC1	RGD	RGD:621002
Bos taurus	RABAC1	VGNC	VGNC:33666
Macaca mulatta	RABAC1	VGNC	VGNC:76639
Felis catus	RABAC1	VGNC	VGNC:69206
Mus musculus	RABAC1	MGD	MGI:1201692
Canis familiaris	RABAC1	VGNC	VGNC:45299
Others	RABAC1	NCBI