TRIM32 - tripartite motif containing 32 Gene

Also Known as HT2A; BBS11; TATIP; LGMD2H; LGMDR8

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 22954

About TRIM32

Cytogenetic location: 9q33.1 Genomic coordinates (GRCh38): 9:116,687,305-116,701,299 (from NCBI)

This gene has 3 transcripts (splice variants), 193 orthologues, 80 paralogues and is associated with 6 phenotypes. Ubiquitous expression in endometrium (RPKM 1.6), adrenal (RPKM 1.5) and 24 other tissues.

Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes. [provided by RefSeq, Jul 2008]

TRIM32 Products (5)

mRNA	Protein	Name
NM_001099679.2	NP_001093149.1	E3 ubiquitin-protein ligase TRIM32
NM_001379048.1	NP_001365977.1	E3 ubiquitin-protein ligase TRIM32
NM_001379049.1	NP_001365978.1	E3 ubiquitin-protein ligase TRIM32
NM_001379050.1	NP_001365979.1	E3 ubiquitin-protein ligase TRIM32
NM_012210.4	NP_036342.2	E3 ubiquitin-protein ligase TRIM32

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	22493164	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA
enables protein-macromolecule adaptor activity	IDA IDA: Inferred from direct assay	28898289	GOA
enables transcription coactivator activity	IDA IDA: Inferred from direct assay	23077300	GOA
enables ubiquitin binding	IDA IDA: Inferred from direct assay	19349376	GOA
enables ubiquitin protein ligase activity	IDA IDA: Inferred from direct assay	16816390	GOA
enables ubiquitin protein ligase activity	IMP IMP: Inferred from mutant phenotype	37943659	GOA
enables ubiquitin-protein transferase activity	IDA IDA: Inferred from direct assay	19349376	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in autophagosome assembly	IDA IDA: Inferred from direct assay	37943659	GOA
involved in cellular response to stress	IDA IDA: Inferred from direct assay	37943659	GOA
involved in free ubiquitin chain polymerization	IDA IDA: Inferred from direct assay	31123703	GOA
involved in innate immune response	IDA IDA: Inferred from direct assay	18248090	GOA
involved in negative regulation of cilium assembly	IDA IDA: Inferred from direct assay	28498859	GOA
involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	IDA IDA: Inferred from direct assay	18632609	GOA
involved in negative regulation of toll-like receptor 4 signaling pathway	IDA IDA: Inferred from direct assay	28898289	GOA
involved in negative regulation of viral transcription	IDA IDA: Inferred from direct assay	18248090	GOA
involved in positive regulation of DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	23077300	GOA
involved in positive regulation of NF-kappaB transcription factor activity	IDA IDA: Inferred from direct assay	23077300	GOA
involved in positive regulation of autophagosome assembly	IDA IDA: Inferred from direct assay	37943659	GOA
involved in positive regulation of autophagy	IDA IDA: Inferred from direct assay	31123703	GOA
involved in positive regulation of canonical NF-kappaB signal transduction	IDA IDA: Inferred from direct assay	23077300	GOA
involved in positive regulation of cell cycle	IDA IDA: Inferred from direct assay	18632609	GOA
involved in positive regulation of cell growth	IDA IDA: Inferred from direct assay	18632609	GOA
involved in positive regulation of cell migration	IDA IDA: Inferred from direct assay	18632609	GOA
involved in positive regulation of proteolysis	IDA IDA: Inferred from direct assay	18632609	GOA
involved in protein K63-linked ubiquitination	IDA IDA: Inferred from direct assay	37943659	GOA
involved in protein polyubiquitination	IDA IDA: Inferred from direct assay	18632609	GOA
involved in protein ubiquitination	IDA IDA: Inferred from direct assay	16816390	GOA
involved in response to oxidative stress	IDA IDA: Inferred from direct assay	37943659	GOA
involved in response to starvation	IDA IDA: Inferred from direct assay	37943659	GOA
involved in suppression of viral release by host	IDA IDA: Inferred from direct assay	18248090	GOA
involved in ubiquitin-dependent protein catabolic process	IMP IMP: Inferred from mutant phenotype	19349376	GOA

Cellular Component GO Annotation	Evidence	References	Source
is active in autophagosome	IDA IDA: Inferred from direct assay	37943659	GOA
is active in centrosome	IDA IDA: Inferred from direct assay	28498859	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	19349376	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRIM32 Protein Structure

zf-RING_UBOX

NHL

0
100
200
300
400
500
600
653 a.a.

Protein Preferred Names	Protein Names
E3 ubiquitin-protein ligase TRIM32	72 kDa Tat-interacting protein

TRIM32 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0-2	Validated Y2H	25416956
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0-2	Y2H Array	25416956
Intra	TRIM32	Q13049	b3kpu6_human	Homo sapiens	B3KPU6	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	b3kpu6_human	Homo sapiens	B3KPU6	Y2H Array	25416956
Intra	TRIM32	Q13049	SYT6	Homo sapiens	Q5T7P8-2	Validated Y2H	25416956
Intra	TRIM32	Q13049	SYT6	Homo sapiens	Q5T7P8-2	Validated Y2H	32296183
Intra	TRIM32	Q13049	SYT6	Homo sapiens	Q5T7P8-2	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	UBE2V1	Homo sapiens	Q13404	Validated Y2H	32296183
Intra	TRIM32	Q13049	UBE2N	Homo sapiens	P61088	Y2H Array	19549727
Intra	TRIM32	Q13049	UBE2N	Homo sapiens	P61088	Y2H Array	19690564
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9-2	Y2H Array	32296183
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9-2	SLC	25910212
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9-2	Validated Y2H	25910212
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9-2	Y2H Array	25910212
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9-2	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9-2	Validated Y2H	32296183
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9-2	Y2H Bait-Prey Pool	25910212
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083-2	Y2H Array	32296183
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083-2	SLC	25910212
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083-2	Validated Y2H	25910212
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083-2	Y2H Bait-Prey Pool	25910212
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083-2	Y2H Array	25910212
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083-2	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	TCEANC	Homo sapiens	Q8N8B7-2	Validated Y2H	32296183
Intra	TRIM32	Q13049	PTCD2	Homo sapiens	Q8WV60	Validated Y2H	32296183
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083-4	Y2H Array	26871637
Intra	TRIM32	Q13049	SEC23IP	Homo sapiens	Q9Y6Y8	Anti Tag CoIP	33961781
Intra	TRIM32	Q13049	SEC23IP	Homo sapiens	Q9Y6Y8	TAP	27173435
Intra	TRIM32	Q13049	GPR137B	Homo sapiens	O60478	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	GPR137B	Homo sapiens	O60478	Y2H Array	32296183
Intra	TRIM32	Q13049	UBE2U	Homo sapiens	Q5VVX9	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	UBE2U	Homo sapiens	Q5VVX9	Y2H Array	19549727
Intra	TRIM32	Q13049	UBE2U	Homo sapiens	Q5VVX9	Validated Y2H	25416956
Intra	TRIM32	Q13049	PTPN11	Homo sapiens	Q06124	Y2H Pooling	27229929
Intra	TRIM32	Q13049	FADS6	Homo sapiens	Q8N9I5	Validated Y2H	32296183
Intra	TRIM32	Q13049	FADS6	Homo sapiens	Q8N9I5	Y2H Array	32296183
Intra	TRIM32	Q13049	FADS6	Homo sapiens	Q8N9I5	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	DERL1	Homo sapiens	Q9BUN8	Y2H Array	32296183
Intra	TRIM32	Q13049	DERL1	Homo sapiens	Q9BUN8	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	DERL1	Homo sapiens	Q9BUN8	Validated Y2H	32296183
Intra	TRIM32	Q13049	KCTD9	Homo sapiens	Q7L273	Validated Y2H	32296183
Intra	TRIM32	Q13049	KCTD9	Homo sapiens	Q7L273	Y2H Array	25416956
Intra	TRIM32	Q13049	KCTD9	Homo sapiens	Q7L273	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	PELI2	Homo sapiens	Q9HAT8	Validated Y2H	32296183
Intra	TRIM32	Q13049	CLIP4	Homo sapiens	Q8N3C7	Validated Y2H	32296183
Intra	TRIM32	Q13049	CLIP4	Homo sapiens	Q8N3C7	Y2H Array	25416956
Intra	TRIM32	Q13049	UBQLN4	Homo sapiens	Q9NRR5	Pull Down	16713569
Intra	TRIM32	Q13049	UBQLN4	Homo sapiens	Q9NRR5	Y2H Array	16713569
Intra	TRIM32	Q13049	AKTIP	Homo sapiens	Q9H8T0	Y2H Fragment Pooling	23414517
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	Validated Y2H	25910212
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	Y2H Bait-Prey Pool	25910212
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	Y2H Array	25910212
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	Validated Y2H	32296183
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	SLC	25910212
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	Y2H Array	32296183
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	RABAC1	Homo sapiens	Q9UI14	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	SDCBP	Homo sapiens	O00560	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	SDCBP	Homo sapiens	O00560	Validated Y2H	25416956
Intra	TRIM32	Q13049	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	32296183
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0	Y2H Pooling	16189514
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32296183
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	25416956
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	32296183
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	25416956
Intra	TRIM32	Q13049	PDE9A	Homo sapiens	O76083	Validated Y2H	25416956
Intra	TRIM32	Q13049	SCGB1A1	Homo sapiens	P11684	Y2H	21516116
Intra	TRIM32	Q13049	SCGB1A1	Homo sapiens	P11684	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	SCGB1A1	Homo sapiens	P11684	Validated Y2H	25416956
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9	Y2H Prey Pooling	25416956
Intra	TRIM32	Q13049	ABI2	Homo sapiens	Q9NYB9	Y2H Array	29892012
Intra	TRIM32	Q13049	MOB1A	Homo sapiens	Q9H8S9	Validated Y2H	32296183
Intra	TRIM32	Q13049	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
Intra	TRIM32	Q13049	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
Intra	TRIM32	Q13049	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	TTC23	Homo sapiens	Q5W5X9-3	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	TTC23	Homo sapiens	Q5W5X9-3	Validated Y2H	32296183
Intra	TRIM32	Q13049	TTC23	Homo sapiens	Q5W5X9-3	Y2H Array	32296183
Intra	TRIM32	Q13049	ATXN1	Homo sapiens	P54253	Y2H Array	16713569
Intra	TRIM32	Q13049	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
Intra	TRIM32	Q13049	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	TRIM32	Q13049	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

TRIM32 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P87120	TRIM32 Antibody (YA6813)	WB	Human, Mouse

Related Diseases

Diseases	Alias
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 8	Sarcotubular Myopathy Lgmd2h Muscular Dystrophy, Limb-Girdle, Type 2h Limb-Girdle Muscular Dystrophy Type 2h LGMDR8 Muscular Dystrophy Hutterite Type Muscular Dystrophy, Hutterite Type Muscular Dystrophy Limb-Girdle Type 2h Trim32-Related Limb-Girdle Muscular Dystrophy R8 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2h Lgmd Due To Trim32 Deficiency Lgmd Type 2h Limb-Girdle Muscular Dystrophy Due To Trim32 Deficiency Trim32-Related Lgmd R8 Limb-Girdle Muscular Dystrophy 2h Dystrophy, Muscular, Limb-Girdle, Type 2h
Bardet-Biedl Syndrome 11	BBS11 Bardet-Biedl Syndrome Bbs Bardet-Biedl Syndrome, Type 11
Bardet-Biedl Syndrome	Bbs Biedl-Bardet Syndrome
Isolated Elevated Serum Creatine Phosphokinase Levels	Elevated Serum Cpk Idiopathic Hyperckemia Isolated Hyperckemia Elevated Serum Creatine Phosphokinase H-Ck Idiopathic Persistent Elevation Of Serum Creatine Kinase
Creatine Phosphokinase, Elevated Serum	Hyperckemia, Idiopathic Cpk, Elevated Serum Hyperckmia HYPCK
Myopathy	Muscular Diseases Myopathies
Limb-Girdle Muscular Dystrophy	Lgmd Limb Girdle Muscular Dystrophy Muscular Dystrophies, Limb-Girdle Erb'S Muscular Dystrophy Leyden-Mbius Muscular Dystrophy Limb-Girdle Syndrome Myopathic Limb-Girdle Syndrome Limb Girdle Muscular Dystrophy Limb-Girdle Dystrophy, Muscular, Limb-Girdle Lgmd - [Limb-Girdle Muscular Dystrophy] Limb Girdle Muscle Dystrophy Limb-Girdle Myopathy
Autosomal Recessive Limb-Girdle Muscular Dystrophy	Muscular Dystrophy, Limb-Girdle, Autosomal Recessive
Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2h	Lgmd2h Limb-Girdle Muscular Dystrophy Due To Trim32 Deficiency Muscular Dystrophy Hutterite Type Sarcotubular Myopathy Limb-Girdle Muscular Dystrophy Type 2h
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 7	Muscular Dystrophy, Limb-Girdle, Type 2g Lgmd2g LGMDR7 Limb-Girdle Muscular Dystrophy, Type 2g Telethonin-Related Limb-Girdle Muscular Dystrophy R7 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2g Lgmd Due To Telethonin Deficiency Lgmd Type 2g Limb-Girdle Muscular Dystrophy Due To Telethonin Deficiency Limb-Girdle Muscular Dystrophy Type 2g Telethonin-Related Lgmd R7 Limb-Girdle Muscular Dystrophy 2g Dystrophy, Muscular, Limb-Girdle, Type 2g
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 4	Lgmd2e Muscular Dystrophy, Limb-Girdle, Type 2e LGMDR4 Beta-Sarcoglycan-Related Limb-Girdle Muscular Dystrophy R4 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2e Beta-Sarcoglycan-Related Lgmd R4 Beta-Sarcoglycanopathy Lgmd Due To Beta-Sarcoglycan Deficiency Lgmd Type 2e Limb-Girdle Muscular Dystrophy Due To Beta-Sarcoglycan Deficiency Limb-Girdle Muscular Dystrophy Type 2e Limb-Girdle Muscular Dystrophy 2e
Muscular Dystrophy	Muscular Dystrophies Congenital Md Congenital Muscular Dystrophy Cmd Mdc Dystrophy, Muscular Gower'S Muscular Dystrophy Progressive Musclular Dystrophy Pseudohypertrophic Atrophy Pseudohypertrophic Muscle Paralysis Pseudohypertrophic Muscular Atrophy Pseudohypertrophic Muscular Dystrophy Pseudohypertrophic Paralysis Pseudomuscular Hypertrophy
Muscular Dystrophy-Dystroglycanopathy , Type C, 5	Lgmd2i Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2i MDDGC5 Limb-Girdle Muscular Dystrophy Due To Fkrp Deficiency Limb-Girdle Muscular Dystrophy Type 2i Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 9 Lgmdr9 Muscular Dystrophy, Limb-Girdle, Type 2i Muscular Dystrophy-Dystroglycanopathy Limb-Girdle Frkp-Related Fkrp-Related Limb-Girdle Muscular Dystrophy R9 Fkrp-Related Lgmd R9 Lgmd Due To Fkrp Deficiency Lgmd Type 2i Muscular Dystrophy-Dystroglycanopathy, Limb-Girdle, Frkp-Related Muscular Dystrophy Limb-Girdle Type 2i Muscular Dystrophy-Dystroglycanopathy Type C 5 Muscular Dystrophy-Dystroglycanopathy Limb-Girdle C5 Dystrophy, Muscular, Limb-Girdle, Type 2i
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 6	Lgmd2f Muscular Dystrophy, Limb-Girdle, Type 2f Limb-Girdle Muscular Dystrophy Type 2f LGMDR6 Muscular Dystrophy Limb-Girdle With Delta-Sarcoglyan Deficiency Delta-Sarcoglycan-Related Limb-Girdle Muscular Dystrophy R6 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2f Delta-Sarcoglycan-Related Lgmd R6 Delta-Sarcoglycanopathy Lgmd Due To Delta-Sarcoglycan Deficiency Lgmd Type 2f Limb-Girdle Muscular Dystrophy Due To Delta-Sarcoglycan Deficiency Limb-Girdle Muscular Dystrophy 2f Limb-Girdle Muscular Dystrophy, Type 2f Dystrophy, Muscular, Limb-Girdle, Type 2f
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 2	Lgmd2b Muscular Dystrophy, Limb-Girdle, Type 2b Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2e Beta-Sarcoglycanopathy Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2y Muscular Dystrophy, Limb-Girdle, Type 3 Lgmd3 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2s LGMDR2 Muscular Dystrophy, Limb-Girdle, Type 2s Limb-Girdle Muscular Dystrophy Type 2b Lgmd2e Limb-Girdle Muscular Dystrophy Due To Beta-Sarcoglycan Deficiency Muscular Dystrophy, Limb-Girdle, Type 2e Lgmd2s Autosomal Recessive Muscular Dystrophy Due To Lap1b Deficiency Autosomal Recessive Muscular Dystrophy Due To Torsin-1a-Interacting Protein 1 Deficiency Lgmd2y Muscular Dystrophy With Progressive Weakness, Distal Contractures And Rigid Spine Muscular Dystrophy, Limb-Girdle, Type 2y Dysferlin-Related Limb-Girdle Muscular Dystrophy R2 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2b Dysferlin-Related Lgmd R2 Lgmd Due To Dysferlin Deficiency Lgmd Type 2b Limb-Girdle Muscular Dystrophy Due To Dysferlin Deficiency Limb-Girdle Muscular Dystrophy 2b Limb-Girdle Muscular Dystrophy, Type 2b Dystrophy, Muscular, Limb-Girdle, Autosomal Recessive, Type 2 Dystrophy, Muscular, Limb-Girdle, Type 2b Limb-Girdle Muscular Dystrophy, Type 2e
Limb-Girdle Muscular Dystrophy Type 1a	Lgmd1a Lgmd1 Muscular Dystrophy, Proximal, Type 1a Limb-Girdle Muscular Dystrophy, Type 1a Dystrophy, Muscular, Limb-Girdle, Type 1a
Joubert Syndrome 6	JBTS6 Joubert Syndrome, Type 6
Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2j	Lgmd2j Muscular Dystrophy, Limb-Girdle, Type 2j
Polydactyly	Non-Syndromic Polydactyly Polydactyly, Postaxial Postaxial Polydactyly Supernumerary Digit Extra Digits Hyperdactyly Polydactylia Polydactylism Supernumerary Digits
Melancholia
Myopathy, Spheroid Body	Spheroid Body Myopathy Autosomal Dominant Spheroid Body Myopathy SBM
Mulibrey Nanism	MUL Muscle-Liver-Brain-Eye Nanism Pericardial Constriction And Growth Failure Perheentupa Syndrome Mulibrey Growth Disorder Mulibrey Nanism Syndrome Pericardial Constriction With Growth Failure Nanism Mulibrey
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Myoclonic Epilepsy Of Lafora	Lafora Disease Epilepsy, Progressive Myoclonic 2b EPM2 Melf Epilepsy, Progressive Myoclonic 2a Epm2a Lafora'S Disease Lafora Body Disease Lbd Epilepsy, Progressive Myoclonic, 2a Lafora Progressive Myoclonic Epilepsy Epilepsy Progressive Myoclonic 2 Lafora Body Disorder Pme Type 2 Progressive Myoclonic Epilepsy Type 2 Progressive Myoclonus Epilepsy Type 2 Epilepsy, Progressive Myoclonic 2 Epm2b Ld Progressive Myoclonic Epilepsy 2 Progressive Myoclonic Epilepsy 2a Progressive Myoclonic Epilepsy 2b Progressive Myoclonic Epilepsy Lafora Type Epilepsy, Myoclonic, Of Lafora
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Psychotic Disorder	Psychotic Disorders Mental Or Behavioural Disorder Psychotic Mental Disorders
Myofibrillar Myopathy	Desmin Related Myopathy Myotilinopathy Myopathy, Myofibrillar Alpha Beta Crystallinopathy Desmin Storage Myopathy Desminopathy Filaminopathy Protein Surplus Myopathy Zaspopathy Myofibrillar Myopathies Myopathy, Myofibrillar, Desmin-Related Myopathy, Desmin Storage Mfm - [Myofibrillar Myopathy]
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Fundus Dystrophy	Retinal Dystrophy Retinal Dystrophies Dystrophy, Retinal
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15037	TRIM32 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21208	Trim32 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27724	Trim32 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TRIM32	VGNC	VGNC:36328
Felis catus	TRIM32	VGNC	VGNC:66534
Canis familiaris	TRIM32	VGNC	VGNC:47814
Rattus norvegicus	TRIM32	RGD	RGD:1305238
Mus musculus	TRIM32	MGD	MGI:1917057
Macaca mulatta	TRIM32	VGNC	VGNC:79032
Others	TRIM32	NCBI