PTCD2 - pentatricopeptide repeat domain 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79810

Summary

Enables RNA binding activity. Predicted to be involved in mitochondrion organization and regulation of mRNA processing. Predicted to act upstream of or within several processes, including liver development; muscle cell development; and ventricular cardiac muscle tissue morphogenesis. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 1.9), brain (RPKM 1.5) and 25 other tissues.

PTCD2 Products (4)

mRNA Protein Name
NM_001284403.2 NP_001271332.1 pentatricopeptide repeat-containing protein 2, mitochondrial isoform 2
NM_001284404.2 NP_001271333.1 pentatricopeptide repeat-containing protein 2, mitochondrial isoform 3
NM_001284405.2 NP_001271334.1 pentatricopeptide repeat-containing protein 2, mitochondrial isoform 4
NM_024754.5 NP_079030.3 pentatricopeptide repeat-containing protein 2, mitochondrial isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
18729827 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PTCD2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PTCD2 Q8WV60 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
PTCD2 Q8WV60 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
PTCD2 Q8WV60 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
PTCD2 Q8WV60 MID1 Homo sapiens O15344
Y2H Prey Pooling
32296183
Intra
PTCD2 Q8WV60 MID1 Homo sapiens O15344
Y2H Array
32296183
Intra
PTCD2 Q8WV60 TRIM32 Homo sapiens Q13049
Y2H Array
32296183
Intra
PTCD2 Q8WV60 TRIM32 Homo sapiens Q13049
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W011009 PTCDA ≥98.0% Unkown
HY-D0285 3,4,9,10-Perylenetetracarboxylic-diimide / Unkown
HY-P5922 PTD2 Inhibitor / Unkown
HY-RS10191 PDCD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11354 PTCD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11355 PTCD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11357 PTCH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21684 Pdcd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21703 Ptcd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22751 Ptch2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28202 Pdcd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28221 Ptcd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29265 Ptch2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W251144 N,N′-Dipentyl-3,4,9,10-perylenedicarboximide / Unkown