CLIP4 - CAP-Gly domain containing linker protein family member 4 Gene

Also Known as RSNL2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79745

About CLIP4

This gene has 45 transcripts (splice variants), 205 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 10.8), skin (RPKM 7.6) and 23 other tissues.

Summary

Predicted to enable microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

CLIP4 Products (4)

mRNA Protein Name
NM_001287527.2 NP_001274456.1 CAP-Gly domain-containing linker protein 4 isoform 1
NM_001287528.2 NP_001274457.1 CAP-Gly domain-containing linker protein 4 isoform 2
NM_001410747.1 NP_001397676.1 CAP-Gly domain-containing linker protein 4 isoform 3
NM_024692.6 NP_078968.3 CAP-Gly domain-containing linker protein 4 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLIP4 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (129 - 217)

CAP_GLY

CAP_GLY: CAP-Gly domain (285 - 349)

CAP_GLY

CAP_GLY: CAP-Gly domain (487 - 552)

CAP_GLY

CAP_GLY: CAP-Gly domain (627 - 690)

  • 0
  • 200
  • 400
  • 600
  • 705 a.a.
Protein Preferred Names Protein Names

CAP-Gly domain-containing linker protein 4

  • CAP-GLY domain containing linker protein family, member 4

CLIP4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CLIP4 Q8N3C7 ZNF114 Homo sapiens Q8NC26
Y2H Array
31515488
Intra
CLIP4 Q8N3C7 ZNF114 Homo sapiens Q8NC26
Validated Y2H
25416956
Intra
CLIP4 Q8N3C7 ZNF114 Homo sapiens Q8NC26
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 ZNF114 Homo sapiens Q8NC26
Y2H Prey Pooling
25416956
Intra
CLIP4 Q8N3C7 ZNF114 Homo sapiens Q8NC26
Validated Y2H
32296183
Intra
CLIP4 Q8N3C7 ZNF114 Homo sapiens Q8NC26
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 SIX2 Homo sapiens Q9NPC8
Validated Y2H
32296183
Intra
CLIP4 Q8N3C7 SIX2 Homo sapiens Q9NPC8
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 SIX2 Homo sapiens Q9NPC8
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
CLIP4 Q8N3C7 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 KIFC3 Homo sapiens Q9BVG8
Y2H Array
25416956
Intra
CLIP4 Q8N3C7 KIFC3 Homo sapiens Q9BVG8
Validated Y2H
25416956
Intra
CLIP4 Q8N3C7 MAP7 Homo sapiens Q14244
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 MAP7 Homo sapiens Q14244
Y2H Prey Pooling
32296183
Cross
CLIP4 Q8N3C7 P0DTD1-PRO_0000449630 SARS-CoV-2 P0DTD1-PRO_0000449630
Y2H Array
36217030
Intra
CLIP4 Q8N3C7 TRIP13 Homo sapiens Q15645
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 TRIP13 Homo sapiens Q15645
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
25416956
Intra
CLIP4 Q8N3C7 TRIM32 Homo sapiens Q13049
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 TRIM32 Homo sapiens Q13049
Y2H Prey Pooling
25416956
Intra
CLIP4 Q8N3C7 TRIM32 Homo sapiens Q13049
Validated Y2H
25416956
Intra
CLIP4 Q8N3C7 TRIM32 Homo sapiens Q13049
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 MAGEA12 Homo sapiens P43365
Y2H Array
32296183
Intra
CLIP4 Q8N3C7 MAGEA12 Homo sapiens P43365
Y2H Prey Pooling
32296183
Intra
CLIP4 Q8N3C7 JAKMIP2 Homo sapiens Q96AA8
MAPPIT
25416956
Intra
CLIP4 Q8N3C7 JAKMIP2 Homo sapiens Q96AA8
Validated Y2H
25416956
Intra
CLIP4 Q8N3C7 JAKMIP2 Homo sapiens Q96AA8
Validated Y2H
32296183
Intra
CLIP4 Q8N3C7 JAKMIP2 Homo sapiens Q96AA8
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02813 CLIP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15331 UBASH3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22446 Clip4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CLIP4 RGD RGD:1311049
Felis catus CLIP4 VGNC VGNC:80067
Canis familiaris CLIP4 VGNC VGNC:39345
Mus musculus CLIP4 MGD MGI:1919100
Macaca mulatta CLIP4 VGNC VGNC:81372
Bos taurus CLIP4 VGNC VGNC:27447
Others CLIP4 NCBI