2. Gene
  3. MAP7 - microtubule associated protein 7 Gene

MAP7 - microtubule associated protein 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as EMAP115; E-MAP-115

Gene ID: 9053 | Gene type: protein coding

About MAP7

Cytogenetic location: 6q23.3 Genomic coordinates (GRCh38): 6:136,342,734-136,550,422 (from NCBI)

This gene has 9 transcripts (splice variants), 235 orthologues and 3 paralogues. Broad expression in kidney (RPKM 10.5), brain (RPKM 10.5) and 21 other tissues.

Summary

The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

MAP7 Products(36)

mRNA Protein Name
NM_001198608.3 NP_001185537.1 ensconsin isoform 1
NM_001198609.2 NP_001185538.1 ensconsin isoform 2
NM_001198611.3 NP_001185540.1 ensconsin isoform 4
NM_001198614.2 NP_001185543.1 ensconsin isoform 1
NM_001198615.3 NP_001185544.1 ensconsin isoform 5
NM_001198616.3 NP_001185545.1 ensconsin isoform 6
NM_001198617.3 NP_001185546.1 ensconsin isoform 7
NM_001198618.2 NP_001185547.1 ensconsin isoform 8
NM_001198619.2 NP_001185548.1 ensconsin isoform 8
NM_001388328.1 NP_001375257.1 ensconsin isoform 2
NM_001388329.1 NP_001375258.1 ensconsin isoform 2
NM_001388330.1 NP_001375259.1 ensconsin isoform 2
NM_001388331.1 NP_001375260.1 ensconsin isoform 9
NM_001388332.1 NP_001375261.1 ensconsin isoform 1
NM_001388333.1 NP_001375262.1 ensconsin isoform 1
NM_001388334.1 NP_001375263.1 ensconsin isoform 10
NM_001388335.1 NP_001375264.1 ensconsin isoform 11
NM_001388336.1 NP_001375265.1 ensconsin isoform 12
NM_001388337.1 NP_001375266.1 ensconsin isoform 12
NM_001388338.1 NP_001375267.1 ensconsin isoform 12
NM_001388339.1 NP_001375268.1 ensconsin isoform 13
NM_001388340.1 NP_001375269.1 ensconsin isoform 4
NM_001388341.1 NP_001375270.1 ensconsin isoform 4
NM_001388342.1 NP_001375271.1 ensconsin isoform 14
NM_001388343.1 NP_001375272.1 ensconsin isoform 15
NM_001388344.1 NP_001375273.1 ensconsin isoform 16
NM_001388345.1 NP_001375274.1 ensconsin isoform 17
NM_001388346.1 NP_001375275.1 ensconsin isoform 17
NM_001388347.1 NP_001375276.1 ensconsin isoform 18
NM_001388348.1 NP_001375277.1 ensconsin isoform 8
NM_001388349.1 NP_001375278.1 ensconsin isoform 8
NM_001388350.1 NP_001375279.1 ensconsin isoform 20
NM_001388351.1 NP_001375280.1 ensconsin isoform 20
NM_001388352.1 NP_001375281.1 ensconsin isoform 21
NM_001388353.1 NP_001375282.1 ensconsin isoform 22
NM_003980.6 NP_003971.1 ensconsin isoform 3

MAP7 Protein Structure

MAP7

MAP7: MAP7 (E-MAP-115) family (456 - 625)

  • 0
  • 200
  • 400
  • 600
  • 749 a.a.
Protein Preferred Names Protein Names

ensconsin

dJ325F22.2 (microtubule-associated protein 7 (EMAP115, E-MAP-115))

Related Diseases

Diseases Alias
Spondylometaphyseal Dysplasia, Kozlowski Type

Spondylometaphyseal Dysplasia Kozlowski Type

Jequier Kozlowski Skeletal Dysplasia

Smd Kozlowski Type

SMDK

Dysmorphism Arthrogryposis Skeletal Maturation Advanced

Jequier-Kozlowski Syndrome

Skeletal Dysplasia Jequier-Kozlowski Type

Smd, Kozlowski Type
Epiphyseal Dysplasia, Multiple, 4

EDM4

Multiple Epiphyseal Dysplasia 4

Multiple Epiphyseal Dysplasia With Clubfoot

Multiple Epiphyseal Dysplasia Type 4

Multiple Epiphyseal Dysplasia, Autosomal Recessive

Multiple Epiphyseal Dysplasia With Bilayered Patellae

Med4

Polyepiphyseal Dysplasia Type 4

Rmed

Autosomal Recessive Multiple Epiphyseal Dysplasia

Multiple Epiphyseal Dysplasia With Bilateral Patellae

Epiphyseal Dysplasia Multiple 4

Multiple Epiphyseal Dysplasia With Double-Layered Patella

Dysplasia, Epiphyseal, Multiple, Type 4
Barrett'S Adenocarcinoma

Barrett Adenocarcinoma

Adenocarcinoma Arising In Barrett'S Mucosa
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08087 MAP7 Human Pre-designed siRNA Set A / Unkown
HY-RS08088 MAP7D1 Human Pre-designed siRNA Set A / Unkown
HY-RS08089 MAP7D2 Human Pre-designed siRNA Set A / Unkown
HY-RS08090 MAP7D3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MAP7 VGNC VGNC:97499
Rattus norvegicus MAP7 RGD RGD:1308866
Bos taurus MAP7 VGNC VGNC:31210
Macaca mulatta MAP7 VGNC VGNC:97788
Canis familiaris MAP7 VGNC VGNC:42987
Mus musculus MAP7 MGD MGI:1328328