JAKMIP2 - janus kinase and microtubule interacting protein 2 Gene

Also Known as NECC1; JAMIP2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9832

About JAKMIP2

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:147,585,438-147,782,728 (from NCBI)

This gene has 6 transcripts (splice variants), 208 orthologues and 2 paralogues. Biased expression in brain (RPKM 6.2), adrenal (RPKM 0.9) and 5 other tissues.

Summary

The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

JAKMIP2 Products (4)

mRNA Protein Name
NM_001270934.2 NP_001257863.1 janus kinase and microtubule-interacting protein 2 isoform 2
NM_001270941.2 NP_001257870.1 janus kinase and microtubule-interacting protein 2 isoform 1
NM_001282282.2 NP_001269211.1 janus kinase and microtubule-interacting protein 2 isoform 4
NM_014790.5 NP_055605.2 janus kinase and microtubule-interacting protein 2 isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

janus kinase and microtubule-interacting protein 2

  • CTCL tumor antigen HD-CL-04

JAKMIP2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
JAKMIP2 Q96AA8 a8k932_human Homo sapiens A8K932
Validated Y2H
25416956
Intra
JAKMIP2 Q96AA8 a8k932_human Homo sapiens A8K932
Y2H Array
25416956
Intra
JAKMIP2 Q96AA8 a8k932_human Homo sapiens A8K932
Y2H Prey Pooling
25416956
Intra
JAKMIP2 Q96AA8 CLASP1 Homo sapiens Q7Z460-4
Validated Y2H
25416956
Intra
JAKMIP2 Q96AA8 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
25416956
Intra
JAKMIP2 Q96AA8 EFHC2 Homo sapiens Q5JST6
Validated Y2H
25416956
Intra
JAKMIP2 Q96AA8 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra
JAKMIP2 Q96AA8 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra
JAKMIP2 Q96AA8 CCDC88B Homo sapiens A6NC98
Y2H Prey Pooling
32296183
Intra
JAKMIP2 Q96AA8 CCDC88B Homo sapiens A6NC98
Y2H Array
32296183
Intra
JAKMIP2 Q96AA8 SMARCE1 Homo sapiens Q969G3
Y2H Prey Pooling
25416956
Intra
JAKMIP2 Q96AA8 MRPL11 Homo sapiens Q9Y3B7
Y2H Array
25416956
Intra
JAKMIP2 Q96AA8 CLIP4 Homo sapiens Q8N3C7
Y2H Prey Pooling
32296183
Intra
JAKMIP2 Q96AA8 CLIP4 Homo sapiens Q8N3C7
Y2H Array
32296183
Intra
JAKMIP2 Q96AA8 CLIP4 Homo sapiens Q8N3C7
Y2H Prey Pooling
25416956
Intra
JAKMIP2 Q96AA8 PIN1 Homo sapiens Q13526
Y2H Array
31515488
Intra
JAKMIP2 Q96AA8 PIN1 Homo sapiens Q13526
Validated Y2H
25416956
Intra
JAKMIP2 Q96AA8 HGS Homo sapiens O14964
Y2H Prey Pooling
25416956
Intra
JAKMIP2 Q96AA8 HGS Homo sapiens O14964
Validated Y2H
25416956
Intra
JAKMIP2 Q96AA8 ELOA Homo sapiens Q14241
Y2H Prey Pooling
25416956
Intra
JAKMIP2 Q96AA8 ELOA Homo sapiens Q14241
Validated Y2H
25416956
Intra
JAKMIP2 Q96AA8 ZNF263 Homo sapiens O14978
Y2H Array
32296183
Intra
JAKMIP2 Q96AA8 ZNF263 Homo sapiens O14978
Y2H Prey Pooling
32296183
Intra
JAKMIP2 Q96AA8 NAB2 Homo sapiens Q15742
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

JAKMIP2 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P810103 JAKMIP2 Antibody (YA9447) WB, ICC/IF, IF-Tissue, IP, ELISA human, mouse, rat
HY-P811303 JAKMIP2 Antibody WB, ICC/IF Human, Mouse, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS07025 JAKMIP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta JAKMIP2 VGNC VGNC:73926
Mus musculus JAKMIP2 MGD MGI:1923467
Bos taurus JAKMIP2 VGNC VGNC:30368
Canis familiaris JAKMIP2 VGNC VGNC:42178
Felis catus JAKMIP2 VGNC VGNC:62999
Rattus norvegicus JAKMIP2 RGD RGD:1559742
Others JAKMIP2 NCBI