ZFPL1 - zinc finger protein like 1 Gene

Also Known as MCG4; D11S750

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7542

About ZFPL1

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:65,084,222-65,088,398 (from NCBI)

This gene has 15 transcripts (splice variants) and 185 orthologues. Ubiquitous expression in testis (RPKM 12.5), ovary (RPKM 11.1) and 25 other tissues.

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in vesicle-mediated transport. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

ZFPL1 Products (1)

mRNA	Protein	Name
NM_006782.4	NP_006773.2	zinc finger protein-like 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
zinc finger protein-like 1	zinc finger protein MCG4

ZFPL1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ZFPL1	O95159	LDLRAD1	Homo sapiens	Q5T700	Validated Y2H	32296183
Intra	ZFPL1	O95159	LDLRAD1	Homo sapiens	Q5T700	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	LDLRAD1	Homo sapiens	Q5T700	Y2H Array	32296183
Intra	ZFPL1	O95159	RELL2	Homo sapiens	Q8NC24	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	RELL2	Homo sapiens	Q8NC24	Validated Y2H	32296183
Intra	ZFPL1	O95159	RELL2	Homo sapiens	Q8NC24	Y2H Array	32296183
Intra	ZFPL1	O95159	MRM3	Homo sapiens	Q9HC36	Validated Y2H	32296183
Intra	ZFPL1	O95159	MRM3	Homo sapiens	Q9HC36	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	MRM3	Homo sapiens	Q9HC36	Y2H Array	32296183
Intra	ZFPL1	O95159	PGRMC2	Homo sapiens	O15173	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	PGRMC2	Homo sapiens	O15173	Y2H Array	32296183
Intra	ZFPL1	O95159	SYAP1	Homo sapiens	Q96A49	Y2H Array	32296183
Intra	ZFPL1	O95159	SYAP1	Homo sapiens	Q96A49	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SYAP1	Homo sapiens	Q96A49	Validated Y2H	32296183
Intra	ZFPL1	O95159	SGMS2	Homo sapiens	Q8NHU3	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SGMS2	Homo sapiens	Q8NHU3	Y2H Array	32296183
Intra	ZFPL1	O95159	SGMS2	Homo sapiens	Q8NHU3	Validated Y2H	32296183
Intra	ZFPL1	O95159	TMEM237	Homo sapiens	Q96Q45-2	Validated Y2H	32296183
Intra	ZFPL1	O95159	TMEM237	Homo sapiens	Q96Q45-2	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TMEM237	Homo sapiens	Q96Q45-2	Y2H Array	32296183
Intra	ZFPL1	O95159	HIBADH	Homo sapiens	P31937	Y2H Array	32296183
Intra	ZFPL1	O95159	HIBADH	Homo sapiens	P31937	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	HIBADH	Homo sapiens	P31937	Validated Y2H	32296183
Intra	ZFPL1	O95159	MFF	Homo sapiens	Q9GZY8-5	Y2H Array	32296183
Intra	ZFPL1	O95159	MFF	Homo sapiens	Q9GZY8-5	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	MFF	Homo sapiens	Q9GZY8-5	Validated Y2H	32296183
Intra	ZFPL1	O95159	STX2	Homo sapiens	P32856-2	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	STX2	Homo sapiens	P32856-2	Y2H Array	32296183
Intra	ZFPL1	O95159	STX2	Homo sapiens	P32856-2	Validated Y2H	32296183
Intra	ZFPL1	O95159	CLEC7A	Homo sapiens	Q9BXN2-6	Y2H Array	32296183
Intra	ZFPL1	O95159	CLEC7A	Homo sapiens	Q9BXN2-6	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	CLEC7A	Homo sapiens	Q9BXN2-6	Validated Y2H	32296183
Intra	ZFPL1	O95159	AHNAK2	Homo sapiens	Q8IVF2-3	Validated Y2H	32296183
Intra	ZFPL1	O95159	AHNAK2	Homo sapiens	Q8IVF2-3	Y2H Array	32296183
Intra	ZFPL1	O95159	AHNAK2	Homo sapiens	Q8IVF2-3	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	CD3E	Homo sapiens	P07766	Y2H Array	32296183
Intra	ZFPL1	O95159	CD3E	Homo sapiens	P07766	Validated Y2H	32296183
Intra	ZFPL1	O95159	CD3E	Homo sapiens	P07766	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	ZFPL1	O95159	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FNDC9	Homo sapiens	Q8TBE3	Validated Y2H	32296183
Intra	ZFPL1	O95159	TMPRSS2	Homo sapiens	O15393-2	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TMPRSS2	Homo sapiens	O15393-2	Y2H Array	32296183
Intra	ZFPL1	O95159	MS4A3	Homo sapiens	Q96HJ5	Y2H Array	32296183
Intra	ZFPL1	O95159	MS4A3	Homo sapiens	Q96HJ5	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	MS4A3	Homo sapiens	Q96HJ5	Validated Y2H	32296183
Intra	ZFPL1	O95159	SCN3B	Homo sapiens	Q9NY72	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SCN3B	Homo sapiens	Q9NY72	Validated Y2H	32296183
Intra	ZFPL1	O95159	SCN3B	Homo sapiens	Q9NY72	Y2H Array	32296183
Intra	ZFPL1	O95159	SSMEM1	Homo sapiens	Q8WWF3	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SSMEM1	Homo sapiens	Q8WWF3	Validated Y2H	32296183
Intra	ZFPL1	O95159	SSMEM1	Homo sapiens	Q8WWF3	Y2H Array	32296183
Intra	ZFPL1	O95159	LEUTX	Homo sapiens	A8MZ59	Y2H Array	32296183
Intra	ZFPL1	O95159	LEUTX	Homo sapiens	A8MZ59	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	CPLX4	Homo sapiens	Q7Z7G2	Validated Y2H	32296183
Intra	ZFPL1	O95159	CPLX4	Homo sapiens	Q7Z7G2	Y2H Array	32296183
Intra	ZFPL1	O95159	CPLX4	Homo sapiens	Q7Z7G2	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SHISAL1	Homo sapiens	Q3SXP7	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SHISAL1	Homo sapiens	Q3SXP7	Validated Y2H	32296183
Intra	ZFPL1	O95159	SHISAL1	Homo sapiens	Q3SXP7	Y2H Array	32296183
Intra	ZFPL1	O95159	GPR42	Homo sapiens	O15529	Y2H Array	32296183
Intra	ZFPL1	O95159	GPR42	Homo sapiens	O15529	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SLC10A6	Homo sapiens	Q3KNW5	Validated Y2H	32296183
Intra	ZFPL1	O95159	SLC10A6	Homo sapiens	Q3KNW5	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SLC10A6	Homo sapiens	Q3KNW5	Y2H Array	32296183
Intra	ZFPL1	O95159	FAM209A	Homo sapiens	Q5JX71	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FAM209A	Homo sapiens	Q5JX71	Validated Y2H	32296183
Intra	ZFPL1	O95159	FAM209A	Homo sapiens	Q5JX71	Y2H Array	32296183
Intra	ZFPL1	O95159	ELOVL4	Homo sapiens	Q9GZR5	Validated Y2H	32296183
Intra	ZFPL1	O95159	ELOVL4	Homo sapiens	Q9GZR5	Y2H Array	32296183
Intra	ZFPL1	O95159	ELOVL4	Homo sapiens	Q9GZR5	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TEX29	Homo sapiens	Q8N6K0	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TEX29	Homo sapiens	Q8N6K0	Validated Y2H	32296183
Intra	ZFPL1	O95159	TEX29	Homo sapiens	Q8N6K0	Y2H Array	32296183
Intra	ZFPL1	O95159	CGRRF1	Homo sapiens	Q99675	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	CGRRF1	Homo sapiens	Q99675	Validated Y2H	32296183
Intra	ZFPL1	O95159	CGRRF1	Homo sapiens	Q99675	Y2H Array	32296183
Intra	ZFPL1	O95159	TMEM106C	Homo sapiens	Q9BVX2	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TMEM106C	Homo sapiens	Q9BVX2	Validated Y2H	32296183
Intra	ZFPL1	O95159	TMEM106C	Homo sapiens	Q9BVX2	Y2H Array	32296183
Intra	ZFPL1	O95159	LIME1	Homo sapiens	Q9H400	Y2H Array	32296183
Intra	ZFPL1	O95159	LIME1	Homo sapiens	Q9H400	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	LIME1	Homo sapiens	Q9H400	Validated Y2H	32296183
Intra	ZFPL1	O95159	CLEC10A	Homo sapiens	Q8IUN9	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	CLEC10A	Homo sapiens	Q8IUN9	Validated Y2H	32296183
Intra	ZFPL1	O95159	CLEC10A	Homo sapiens	Q8IUN9	Y2H Array	32296183
Intra	ZFPL1	O95159	MFSD14B	Homo sapiens	Q5SR56	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	MFSD14B	Homo sapiens	Q5SR56	Validated Y2H	32296183
Intra	ZFPL1	O95159	MFSD14B	Homo sapiens	Q5SR56	Y2H Array	32296183
Intra	ZFPL1	O95159	EBP	Homo sapiens	Q15125	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	EBP	Homo sapiens	Q15125	Validated Y2H	32296183
Intra	ZFPL1	O95159	EBP	Homo sapiens	Q15125	Y2H Array	32296183
Intra	ZFPL1	O95159	GORAB	Homo sapiens	Q5T7V8	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	GORAB	Homo sapiens	Q5T7V8	Validated Y2H	32296183
Intra	ZFPL1	O95159	GORAB	Homo sapiens	Q5T7V8	Y2H Array	32296183
Intra	ZFPL1	O95159	FKBP7	Homo sapiens	Q9Y680	Y2H Array	32296183
Intra	ZFPL1	O95159	FKBP7	Homo sapiens	Q9Y680	Validated Y2H	32296183
Intra	ZFPL1	O95159	FKBP7	Homo sapiens	Q9Y680	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	PVR	Homo sapiens	P15151	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	PVR	Homo sapiens	P15151	Validated Y2H	32296183
Intra	ZFPL1	O95159	PVR	Homo sapiens	P15151	Y2H Array	32296183
Intra	ZFPL1	O95159	SLC19A3	Homo sapiens	Q9BZV2	Validated Y2H	32296183
Intra	ZFPL1	O95159	SLC19A3	Homo sapiens	Q9BZV2	Y2H Array	32296183
Intra	ZFPL1	O95159	SLC19A3	Homo sapiens	Q9BZV2	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SLC7A14	Homo sapiens	Q8TBB6	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SLC7A14	Homo sapiens	Q8TBB6	Validated Y2H	32296183
Intra	ZFPL1	O95159	SLC7A14	Homo sapiens	Q8TBB6	Y2H Array	32296183
Intra	ZFPL1	O95159	SYT1	Homo sapiens	P21579	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	SYT1	Homo sapiens	P21579	Validated Y2H	32296183
Intra	ZFPL1	O95159	SYT1	Homo sapiens	P21579	Y2H Array	32296183
Intra	ZFPL1	O95159	TM4SF19	Homo sapiens	Q96DZ7	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TM4SF19	Homo sapiens	Q96DZ7	Validated Y2H	32296183
Intra	ZFPL1	O95159	TM4SF19	Homo sapiens	Q96DZ7	Y2H Array	32296183
Intra	ZFPL1	O95159	FRMD3	Homo sapiens	A2A2Y4	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FRMD3	Homo sapiens	A2A2Y4	Y2H Array	32296183
Intra	ZFPL1	O95159	CREB3L1	Homo sapiens	Q96BA8	Y2H Array	32296183
Intra	ZFPL1	O95159	CREB3L1	Homo sapiens	Q96BA8	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	CREB3L1	Homo sapiens	Q96BA8	Validated Y2H	32296183
Intra	ZFPL1	O95159	BIK	Homo sapiens	Q13323	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	BIK	Homo sapiens	Q13323	Validated Y2H	32296183
Intra	ZFPL1	O95159	BIK	Homo sapiens	Q13323	Y2H Array	32296183
Intra	ZFPL1	O95159	STX1A	Homo sapiens	Q16623	Validated Y2H	32296183
Intra	ZFPL1	O95159	STX1A	Homo sapiens	Q16623	Y2H Array	32296183
Intra	ZFPL1	O95159	STX1A	Homo sapiens	Q16623	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TMEM139	Homo sapiens	Q8IV31	Y2H Array	32296183
Intra	ZFPL1	O95159	TMEM139	Homo sapiens	Q8IV31	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TMEM139	Homo sapiens	Q8IV31	Validated Y2H	32296183
Intra	ZFPL1	O95159	MGST3	Homo sapiens	O14880	Y2H Array	32296183
Intra	ZFPL1	O95159	MGST3	Homo sapiens	O14880	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FKBP8	Homo sapiens	Q14318	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FKBP8	Homo sapiens	Q14318	Validated Y2H	32296183
Intra	ZFPL1	O95159	FKBP8	Homo sapiens	Q14318	Y2H Array	32296183
Intra	ZFPL1	O95159	SMIM3	Homo sapiens	Q9BZL3	Validated Y2H	32296183
Intra	ZFPL1	O95159	SMIM3	Homo sapiens	Q9BZL3	Y2H Array	32296183
Intra	ZFPL1	O95159	SMIM3	Homo sapiens	Q9BZL3	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FATE1	Homo sapiens	Q969F0	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	FATE1	Homo sapiens	Q969F0	Validated Y2H	32296183
Intra	ZFPL1	O95159	FATE1	Homo sapiens	Q969F0	Y2H Array	32296183
Intra	ZFPL1	O95159	STX4	Homo sapiens	Q12846	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	STX4	Homo sapiens	Q12846	Validated Y2H	32296183
Intra	ZFPL1	O95159	STX4	Homo sapiens	Q12846	Y2H Array	32296183
Intra	ZFPL1	O95159	KASH5	Homo sapiens	Q8N6L0	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	KASH5	Homo sapiens	Q8N6L0	Validated Y2H	32296183
Intra	ZFPL1	O95159	KASH5	Homo sapiens	Q8N6L0	Y2H Array	32296183
Intra	ZFPL1	O95159	MRPS18B	Homo sapiens	Q9Y676	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	MRPS18B	Homo sapiens	Q9Y676	Validated Y2H	32296183
Intra	ZFPL1	O95159	MRPS18B	Homo sapiens	Q9Y676	Y2H Array	32296183
Intra	ZFPL1	O95159	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	ERGIC3	Homo sapiens	Q9Y282	Anti Tag CoIP	33961781
Intra	ZFPL1	O95159	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
Intra	ZFPL1	O95159	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
Intra	ZFPL1	O95159	MTERF3	Homo sapiens	Q96E29	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	MTERF3	Homo sapiens	Q96E29	Validated Y2H	32296183
Intra	ZFPL1	O95159	MTERF3	Homo sapiens	Q96E29	Y2H Array	32296183
Intra	ZFPL1	O95159	BSND	Homo sapiens	Q8WZ55	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	BSND	Homo sapiens	Q8WZ55	Validated Y2H	32296183
Intra	ZFPL1	O95159	BSND	Homo sapiens	Q8WZ55	Y2H Array	32296183
Intra	ZFPL1	O95159	MIP	Homo sapiens	P30301	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	MIP	Homo sapiens	P30301	Validated Y2H	32296183
Intra	ZFPL1	O95159	MIP	Homo sapiens	P30301	Y2H Array	32296183
Intra	ZFPL1	O95159	CYBRD1	Homo sapiens	Q53TN4	Validated Y2H	32296183
Intra	ZFPL1	O95159	CYBRD1	Homo sapiens	Q53TN4	Y2H Array	32296183
Intra	ZFPL1	O95159	CYBRD1	Homo sapiens	Q53TN4	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183
Intra	ZFPL1	O95159	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	TSTD2	Homo sapiens	Q5T7W7	Validated Y2H	32296183
Intra	ZFPL1	O95159	KLRC1	Homo sapiens	P26715	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	KLRC1	Homo sapiens	P26715	Y2H Array	32296183
Intra	ZFPL1	O95159	KLRC1	Homo sapiens	P26715	Validated Y2H	32296183
Intra	ZFPL1	O95159	PLEKHO1	Homo sapiens	Q53GL0	Y2H Prey Pooling	32296183
Intra	ZFPL1	O95159	PLEKHO1	Homo sapiens	Q53GL0	Validated Y2H	32296183
Intra	ZFPL1	O95159	PLEKHO1	Homo sapiens	Q53GL0	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Congenital Disorder Of Glycosylation, Type Iii	CDG2I Congenital Disorder Of Glycosylation Type Iii Cdgiii Carbohydrate Deficient Glycoprotein Syndrome Type Iii Congenital Disorder Of Glycosylation Type 2i Cog5-Cdg Cdgiidi Congenital Disorder Of Glycosylation 2i Glycosylation, Congenital Disorder Of, Type Iii Congenital Disorder Of Glycosylation, Type I-Iix
Cohen Syndrome	Pepper Syndrome COH1 Hypotonia, Obesity, And Prominent Incisors Coh Chs1, Formerly Norio Syndrome Obesity-Hypotonia Syndrome Prominent Incisors-Obesity-Hypotonia Syndrome Chs1 Hypotonia-Obesity-Prominent Incisors Stage 4s Neuroblastoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16047	ZFPL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ZFPL1	VGNC	VGNC:37170
Mus musculus	ZFPL1	MGD	MGI:1891017
Rattus norvegicus	ZFPL1	RGD	RGD:1586738
Felis catus	ZFPL1	VGNC	VGNC:67233
Macaca mulatta	ZFPL1	VGNC	VGNC:78827
Canis familiaris	ZFPL1	VGNC	VGNC:48618
Others	ZFPL1	NCBI