TM4SF19 - transmembrane 4 L six family member 19 Gene

Homo sapiens

Also known as OCTM4

Gene ID: 116211 | Gene type: protein coding

About TM4SF19

This gene has 4 transcripts (splice variants), 179 orthologues and 5 paralogues. Biased expression in testis (RPKM 3.1), esophagus (RPKM 0.9) and 10 other tissues.

Summary

The protein encoded by this gene is a member of the four-transmembrane L6 superfamily. Members of this family function in various cellular processes including cell proliferation, motility, and adhesion via their interactions with integrins. In human brain tissue, this gene is expressed at high levels in the parietal lobe, occipital lobe, hippocampus, pons, white matter, corpus callosum, and cerebellum. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017]

TM4SF19 Products(3)

mRNA	Protein	Name
NM_001204897.2	NP_001191826.1	transmembrane 4 L6 family member 19 isoform 2
NM_001204898.2	NP_001191827.1	transmembrane 4 L6 family member 19 isoform 3
NM_138461.4	NP_612470.2	transmembrane 4 L6 family member 19 isoform 1

TM4SF19 Protein Structure

L6_membrane

0
100
209 a.a.

Protein Preferred Names

Protein Names

transmembrane 4 L6 family member 19

osteoclast maturation-associated gene 4 protein

Related Diseases

Diseases

Alias

Immunodeficiency 46

Tfrc-Related Combined Immunodeficiency	IMD46
Cid Due To Tfrc Deficiency	Combined Immunodeficiency Due To Tfrc Deficiency

Chromosome 3q29 Deletion Syndrome

Chromosome 3q29 Microdeletion Syndrome	3q29 Microdeletion Syndrome
3q Subtelomere Deletion Syndrome	3q29 Recurrent Deletion
3qter Deletion	3q29 Deletion Syndrome
Monosomy 3q29	Microdeletion 3q29 Syndrome
Del(3)(Q29)	Monosomy 3qter
3q29 Deletion	Del3q29

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14607	TM4SF19 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TM4SF19	RGD	RGD:1560486
Mus musculus	TM4SF19	MGD	MGI:3645933

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