CIDEB - cell death inducing DFFA like effector b Gene

Homo sapiens

Gene ID: 27141 | Gene type: protein coding

About CIDEB

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,305,187-24,311,435 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 192 orthologues and 3 paralogues. Ubiquitous expression in liver (RPKM 36.3), duodenum (RPKM 31.8) and 24 other tissues.

Summary

Enables identical protein binding activity. Involved in activation of cysteine-type endopeptidase activity; positive regulation of cell death; and positive regulation of release of cytochrome c from mitochondria. Acts upstream of or within apoptotic process. Located in cytosol and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CIDEB Products(9)

mRNA	Protein	Name
NM_001318807.3	NP_001305736.1	cell death activator CIDE-B isoform 1
NM_001393334.1	NP_001380263.1	cell death activator CIDE-B isoform 1
NM_001393335.1	NP_001380264.1	cell death activator CIDE-B isoform 1
NM_001393336.1	NP_001380265.1	cell death activator CIDE-B isoform 1
NM_001393337.1	NP_001380266.1	cell death activator CIDE-B isoform 1
NM_001393338.1	NP_001380267.1	cell death activator CIDE-B isoform 1
NM_001393339.1	NP_001380268.1	cell death activator CIDE-B isoform 1
NM_001393340.1	NP_001380269.1	cell death activator CIDE-B isoform 2
NM_014430.4	NP_055245.2	cell death activator CIDE-B isoform 1

CIDEB Protein Structure

CIDE-N

0
100
200
219 a.a.

Protein Preferred Names

Protein Names

cell death activator CIDE-B

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02712	CIDEB Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CIDEB	RGD	RGD:1310000
Felis catus	CIDEB	VGNC	VGNC:60901
Bos taurus	CIDEB	VGNC	VGNC:27364
Macaca mulatta	CIDEB	VGNC	VGNC:84324
Mus musculus	CIDEB	MGD	MGI:1270844

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