APOL2 - apolipoprotein L2 Gene

Homo sapiens

Also known as APOL3; APOL-II

Gene ID: 23780 | Gene type: protein coding

About APOL2

Cytogenetic location: 22q12.3 Genomic coordinates (GRCh38): 22:36,226,209-36,239,954 (from NCBI)

This gene has 9 transcripts (splice variants), 518 orthologues, 6 paralogues and is associated with 1 phenotype. Ubiquitous expression in appendix (RPKM 11.5), spleen (RPKM 10.5) and 25 other tissues.

Summary

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

APOL2 Products(2)

mRNA	Protein	Name
NM_030882.4	NP_112092.2	apolipoprotein L2
NM_145637.3	NP_663612.2	apolipoprotein L2

APOL2 Protein Structure

ApoL

0
100
200
300
337 a.a.

Protein Preferred Names

Protein Names

apolipoprotein L2

apolipoprotein L, 2

Related Diseases

Diseases

Alias

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Phencyclidine Abuse

Pcp Abuse

Sleeping Sickness

African Trypanosomiasis	African Sleeping Sickness
Trypanosomiasis, Human East-African	Trypanosomiasis, East African
Trypanosomiasis African	Trypanosomiasis, African
Human African Trypanosomiasis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00854	APOL2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	APOL2	VGNC	VGNC:69989
Rattus norvegicus	APOL2	RGD	RGD:1309591

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