MARCHF3 - membrane associated ring-CH-type finger 3 Gene

Also Known as MARCH3; RNF173; MARCH-III

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 115123

Summary

This gene encodes a member of the membrane-associated RING-CH (MARCH) family. The encoded protein is an E3 ubiquitin-protein Ligase that may be involved in regulation of the endosomal transport pathway. [provided by RefSeq, Mar 2013]
Broad expression in testis (RPKM 2.7), heart (RPKM 1.5) and 22 other tissues.

MARCHF3 Products (1)

mRNA Protein Name
NG_033192.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Cellular Component GO Annotation Evidence References Source
located in endosome IDA
IDA: Inferred from direct assay
14722266 GOA
located in lysosome IDA
IDA: Inferred from direct assay
14722266 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MARCHF3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MARCHF3 Q86UD3 APOL2 Homo sapiens Q9BQE5
Validated Y2H
32296183
Intra
MARCHF3 Q86UD3 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
Intra
MARCHF3 Q86UD3 FATE1 Homo sapiens Q969F0
Validated Y2H
32296183
Intra
MARCHF3 Q86UD3 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08143 MARCHF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08144 MARCHF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown