TMEM45B - transmembrane protein 45B Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 120224

About TMEM45B

This gene has 5 transcripts (splice variants), 204 orthologues and 2 paralogues. Biased expression in duodenum (RPKM 57.4), small intestine (RPKM 54.1) and 9 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM45B Products (4)

mRNA Protein Name
NM_001331210.2 NP_001318139.1 transmembrane protein 45B
NM_001331211.2 NP_001318140.1 transmembrane protein 45B
NM_001331212.2 NP_001318141.1 transmembrane protein 45B
NM_138788.5 NP_620143.1 transmembrane protein 45B

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM45B Protein Structure

DUF716

DUF716: Family of unknown function (DUF716) (113 - 235)

  • 0
  • 100
  • 200
  • 275 a.a.
Protein Preferred Names Protein Names

transmembrane protein 45B

TMEM45B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM45B Q96B21 TMEM243 Homo sapiens Q9BU79
Validated Y2H
32296183
Intra
TMEM45B Q96B21 TREX1 Homo sapiens Q9NSU2-1
Validated Y2H
32296183
Intra
TMEM45B Q96B21 TMEM60 Homo sapiens Q9H2L4
Validated Y2H
32296183
Intra
TMEM45B Q96B21 APOL2 Homo sapiens Q9BQE5
Validated Y2H
32296183
Intra
TMEM45B Q96B21 INSIG2 Homo sapiens Q9Y5U4
Validated Y2H
32296183
Intra
TMEM45B Q96B21 DOLK Homo sapiens Q9UPQ8
Validated Y2H
32296183
Intra
TMEM45B Q96B21 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14727 TMEM45B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TMEM45B RGD RGD:1305586
Mus musculus TMEM45B MGD MGI:2384574
Felis catus TMEM45B VGNC VGNC:81925
Canis familiaris TMEM45B VGNC VGNC:47583
Macaca mulatta TMEM45B VGNC VGNC:107656
Bos taurus TMEM45B VGNC VGNC:36089
Others TMEM45B NCBI