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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
94107
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "94107" in MCE Product Catalog:
18
Target:
Forschungsgebiete:
Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 μM; IC90 = 0.009 μM) with minimal cytotoxicity .
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4 Cited Publications
Art. -Nr.: HY-B0597
CAS. Nr.: 114870-03-0
Synonyms: Fondaparin sodium; SR-90107A
Target:
Forschungsgebiete:
Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor.
Synonyms: XNW4107
Target:
Forschungsgebiete:
Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria .
Art. -Nr.: HY-P3828
CAS. Nr.: 923949-88-6
Target:
Forschungsgebiete:
Art. -Nr.: HY-B0597R
CAS. Nr.: 114870-03-0
Synonyms: Fondaparin sodium (Standard); SR-90107A (Standard)
Target:
Forschungsgebiete:
Fondaparinux (sodium) (Standard) is the analytical standard of Fondaparinux (sodium). This product is intended for research and analytical applications. Fondaparinux sodium is an antithrombin-dependent factor Xa inhibitor.
Art. -Nr.: HY-17040R
CAS. Nr.: 206361-99-1
Synonyms: TMC114 (Standard); UIC-94017 (Standard)
Target:
Forschungsgebiete:
Darunavir (Standard) is the analytical standard of Darunavir. This product is intended for research and analytical applications. Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 μM; IC90 = 0.009 μM) with minimal cytotoxicity .
Art. -Nr.: HY-W702908
CAS. Nr.: 1346599-75-4
Target:
Forschungsgebiete:
DM-4107 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4107 inhibits the ability of human liver transporters NTCP, BSEP, MRP3, MRP4 (IC50 values are 95.6, 119, 61.2, 37.9 μM, respectively) and bile acid transport in SCHH cells. DM-4107 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD) .
Art. -Nr.: HY-112585
CAS. Nr.: 1133378-37-6
Synonyms: TMC114-d9; UIC-94017-d9
Target:
Forschungsgebiete:
Darunavir-d9 (TMC114-d9) is the deuterium labeled Darunavir. Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 μM; IC90 = 0.009 μM) with minimal cytotoxicity .
Art. -Nr.: HY-182539
CAS. Nr.: 1202877-06-2
Target:
Forschungsgebiete:
Art. -Nr.: HY-120055
CAS. Nr.: 343250-05-5
Target:
Forschungsgebiete:
CP-94707 is an HIV-1 reverse transcriptase (HIV-1 reverse transcriptase) inhibitor, with an IC50 of 4 μM against wild-type and HIV-1 reverse transcriptase Y181I-Y188L double mutant enzymes, and an IC50 of 10 μM against HIV-1 reverse transcriptase K103N mutant enzyme. CP-94707 inhibits the initiation of negative-strand DNA synthesis primed by tRNA Lys-3, as well as the elongation of DNA synthesis mediated by HIV-1 reverse transcriptase. CP-94707 can be used in studies related to HIV infection .
Art. -Nr.: HY-P75871
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Influenza A H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin / HA Protein (His)
Species:
Source:
Art. -Nr.: HY-P85506
Synonyms: PMI1; CDG1B; FLJ39201; Mannose 6 phosphate isomerase; Mannose-6-phosphate isomerase; MANNOSEPHOSPHATE ISOMERASE; MGC94106; MPI; MPI_HUMAN; Phosphohexomutase; phosphomannose isomerase 1; Phosphomannose isomerase; PMI; PMI1.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
