LY6G6C - lymphocyte antigen 6 family member G6C Gene

Homo sapiens

Also known as G6c; NG24; C6orf24

Gene ID: 80740 | Gene type: protein coding

About LY6G6C

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:31,718,648-31,721,746 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele and 91 orthologues. Restricted expression toward skin (RPKM 160.9).

Summary

LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 Amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]

LY6G6C Products(1)

mRNA	Protein	Name
NM_025261.3	NP_079537.1	lymphocyte antigen 6 complex locus protein G6c precursor

Protein Preferred Names

Protein Names

lymphocyte antigen 6 complex locus protein G6c

lymphocyte antigen 6 complex, locus G6C

Related Diseases

Diseases

Alias

Lynch Syndrome I

Lynch Syndrome 1	Colorectal Cancer, Hereditary Nonpolyposis, Type 1
HNPCC1	Fcc1
Lynch Syndrome Ii	Colon Cancer, Familial Nonpolyposis, Type 1
Coca1	Familial Nonpolyposis Colon Cancer Type 1
Hereditary Nonpolyposis Colorectal Cancer Type 1	Hereditary Non-Polyposis Colorectal Cancer 1
Hereditary Non-Polyposis Colorectal Cancer 3	Hnpcc3
Lynch Cancer Family Syndrome	Lynch Syndrome
Lynch Syndrome Type I	Lynch Syndrome Type Ii
Cancer, Colorectal, Nonpolyposis, Hereditary, Type 1	Hereditary Nonpolyposis Colorectal Cancer
Colorectal Cancer, Hereditary Nonpolyposis, Type 3	Hereditary Non-Polyposis Colon Cancer Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07898	LY6G6C Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	LY6G6C	VGNC	VGNC:63334
Mus musculus	LY6G6C	MGD	MGI:2148930
Rattus norvegicus	LY6G6C	RGD	RGD:1302999
Macaca mulatta	LY6G6C	VGNC	VGNC:74285
Bos taurus	LY6G6C	VGNC	VGNC:31090
Canis familiaris	LY6G6C	VGNC	VGNC:42875

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